diff --git a/src/xenia/base/filesystem.h b/src/xenia/base/filesystem.h
index c8cff150f..cca30dd3f 100644
--- a/src/xenia/base/filesystem.h
+++ b/src/xenia/base/filesystem.h
@@ -14,8 +14,10 @@
 #include <iterator>
 #include <memory>
 #include <string>
+#include <string_view>
 #include <vector>
 
+#include "xenia/base/platform.h"
 #include "xenia/base/string.h"
 
 namespace xe {
@@ -122,6 +124,14 @@ struct FileInfo {
 bool GetInfo(const std::filesystem::path& path, FileInfo* out_info);
 std::vector<FileInfo> ListFiles(const std::filesystem::path& path);
 
+#if XE_PLATFORM_ANDROID
+void AndroidInitialize();
+void AndroidShutdown();
+bool IsAndroidContentUri(const std::string_view source);
+int OpenAndroidContentFileDescriptor(const std::string_view uri,
+                                     const char* mode);
+#endif  // XE_PLATFORM_ANDROID
+
 }  // namespace filesystem
 }  // namespace xe
 
diff --git a/src/xenia/base/filesystem_android.cc b/src/xenia/base/filesystem_android.cc
new file mode 100644
index 000000000..12f5c2d7d
--- /dev/null
+++ b/src/xenia/base/filesystem_android.cc
@@ -0,0 +1,278 @@
+/**
+ ******************************************************************************
+ * Xenia : Xbox 360 Emulator Research Project                                 *
+ ******************************************************************************
+ * Copyright 2022 Ben Vanik. All rights reserved.                             *
+ * Released under the BSD license - see LICENSE in the root for more details. *
+ ******************************************************************************
+ */
+
+#include <android/log.h>
+#include <jni.h>
+#include <cstring>
+
+#include "xenia/base/filesystem.h"
+#include "xenia/base/main_android.h"
+#include "xenia/base/math.h"
+#include "xenia/base/string.h"
+
+namespace xe {
+namespace filesystem {
+
+// Using Android logging because the file system may need to be initialized
+// before logging.
+
+static jobject android_content_resolver_;
+static jclass android_content_resolver_class_;
+static jmethodID android_content_resolver_open_file_descriptor_;
+
+static jclass android_parcel_file_descriptor_class_;
+static jmethodID android_parcel_file_descriptor_detach_fd_;
+
+static jclass android_uri_class_;
+static jmethodID android_uri_parse_;
+
+static bool android_content_resolver_initialized_;
+
+static void AndroidShutdownContentResolver() {
+  android_content_resolver_initialized_ = false;
+  android_uri_parse_ = nullptr;
+  android_parcel_file_descriptor_detach_fd_ = nullptr;
+  android_content_resolver_open_file_descriptor_ = nullptr;
+  JNIEnv* jni_env = GetAndroidThreadJniEnv();
+  if (jni_env) {
+    if (android_uri_class_) {
+      jni_env->DeleteGlobalRef(android_uri_class_);
+    }
+    if (android_parcel_file_descriptor_class_) {
+      jni_env->DeleteGlobalRef(
+          reinterpret_cast<jobject>(android_parcel_file_descriptor_class_));
+    }
+    if (android_content_resolver_class_) {
+      jni_env->DeleteGlobalRef(
+          reinterpret_cast<jobject>(android_content_resolver_class_));
+    }
+    if (android_content_resolver_) {
+      jni_env->DeleteGlobalRef(
+          reinterpret_cast<jobject>(android_content_resolver_));
+    }
+  }
+  android_uri_class_ = nullptr;
+  android_parcel_file_descriptor_class_ = nullptr;
+  android_content_resolver_class_ = nullptr;
+  android_content_resolver_ = nullptr;
+}
+
+static void AndroidInitializeContentResolver() {
+  JNIEnv* jni_env = GetAndroidThreadJniEnv();
+  if (!jni_env) {
+    return;
+  }
+  jobject application_context = GetAndroidApplicationContext();
+  if (!application_context) {
+    return;
+  }
+  {
+    jclass context_class = jni_env->GetObjectClass(application_context);
+    if (!context_class) {
+      __android_log_write(ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+                          "Failed to get the context class");
+      AndroidShutdownContentResolver();
+      return;
+    }
+    jmethodID context_get_content_resolver =
+        jni_env->GetMethodID(context_class, "getContentResolver",
+                             "()Landroid/content/ContentResolver;");
+    if (!context_get_content_resolver) {
+      __android_log_write(
+          ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+          "Failed to get the getContentResolver method of the context");
+      jni_env->DeleteLocalRef(reinterpret_cast<jobject>(context_class));
+      AndroidShutdownContentResolver();
+      return;
+    }
+    jobject content_resolver = jni_env->CallObjectMethod(
+        application_context, context_get_content_resolver);
+    jni_env->DeleteLocalRef(reinterpret_cast<jobject>(context_class));
+    if (!content_resolver) {
+      __android_log_write(ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+                          "Failed to get the content resolver");
+      AndroidShutdownContentResolver();
+      return;
+    }
+    android_content_resolver_ = jni_env->NewGlobalRef(content_resolver);
+    jni_env->DeleteLocalRef(content_resolver);
+  }
+  if (!android_content_resolver_) {
+    __android_log_write(
+        ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+        "Failed to create a global reference to the content resolver");
+    AndroidShutdownContentResolver();
+    return;
+  }
+  {
+    jobject content_resolver_class =
+        jni_env->GetObjectClass(android_content_resolver_);
+    if (!content_resolver_class) {
+      __android_log_write(ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+                          "Failed to get the content resolver class");
+      AndroidShutdownContentResolver();
+      return;
+    }
+    android_content_resolver_class_ =
+        reinterpret_cast<jclass>(jni_env->NewGlobalRef(
+            reinterpret_cast<jobject>(content_resolver_class)));
+    jni_env->DeleteLocalRef(reinterpret_cast<jobject>(content_resolver_class));
+  }
+  if (!android_content_resolver_class_) {
+    __android_log_write(
+        ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+        "Failed to create a global reference to the content resolver class");
+    AndroidShutdownContentResolver();
+    return;
+  }
+  android_content_resolver_open_file_descriptor_ = jni_env->GetMethodID(
+      android_content_resolver_class_, "openFileDescriptor",
+      "(Landroid/net/Uri;Ljava/lang/String;)Landroid/os/ParcelFileDescriptor;");
+  if (!android_content_resolver_open_file_descriptor_) {
+    __android_log_write(
+        ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+        "Failed to get the openFileDescriptor method of the content resolver");
+    AndroidShutdownContentResolver();
+    return;
+  }
+
+  {
+    jclass parcel_file_descriptor_class =
+        jni_env->FindClass("android/os/ParcelFileDescriptor");
+    if (!parcel_file_descriptor_class) {
+      __android_log_write(ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+                          "Failed to get the parcel file descriptor class");
+      AndroidShutdownContentResolver();
+      return;
+    }
+    android_parcel_file_descriptor_class_ =
+        reinterpret_cast<jclass>(jni_env->NewGlobalRef(
+            reinterpret_cast<jobject>(parcel_file_descriptor_class)));
+    jni_env->DeleteLocalRef(
+        reinterpret_cast<jobject>(parcel_file_descriptor_class));
+  }
+  if (!android_parcel_file_descriptor_class_) {
+    __android_log_write(
+        ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+        "Failed to create a global reference to the parcel file descriptor "
+        "class");
+    AndroidShutdownContentResolver();
+    return;
+  }
+  android_parcel_file_descriptor_detach_fd_ = jni_env->GetMethodID(
+      android_parcel_file_descriptor_class_, "detachFd", "()I");
+  if (!android_parcel_file_descriptor_detach_fd_) {
+    __android_log_write(
+        ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+        "Failed to get the detachFd method of the parcel file descriptor");
+    AndroidShutdownContentResolver();
+    return;
+  }
+
+  {
+    jclass uri_class = jni_env->FindClass("android/net/Uri");
+    if (!uri_class) {
+      __android_log_write(ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+                          "Failed to get the URI class");
+      AndroidShutdownContentResolver();
+      return;
+    }
+    android_uri_class_ = reinterpret_cast<jclass>(
+        jni_env->NewGlobalRef(reinterpret_cast<jobject>(uri_class)));
+    jni_env->DeleteLocalRef(reinterpret_cast<jobject>(uri_class));
+  }
+  if (!android_uri_class_) {
+    __android_log_write(ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+                        "Failed to create a global reference to the URI class");
+    AndroidShutdownContentResolver();
+    return;
+  }
+  android_uri_parse_ = jni_env->GetStaticMethodID(
+      android_uri_class_, "parse", "(Ljava/lang/String;)Landroid/net/Uri;");
+  if (!android_uri_parse_) {
+    __android_log_write(ANDROID_LOG_ERROR, "AndroidInitializeContentResolver",
+                        "Failed to get the parse method of the URI class");
+    AndroidShutdownContentResolver();
+    return;
+  }
+
+  android_content_resolver_initialized_ = true;
+}
+
+void AndroidInitialize() { AndroidInitializeContentResolver(); }
+
+void AndroidShutdown() { AndroidShutdownContentResolver(); }
+
+bool IsAndroidContentUri(const std::string_view source) {
+  // A URI schema is case-insensitive. Though just content: defines the schema,
+  // still including // in the comparison to distinguish from a file with a name
+  // starting from content: (as this is the main purpose of this code -
+  // separating URIs from file paths) more clearly.
+  static const char kContentSchema[] = "content://";
+  constexpr size_t kContentSchemaLength = xe::countof(kContentSchema) - 1;
+  return source.size() >= kContentSchemaLength &&
+         !xe_strncasecmp(source.data(), kContentSchema, kContentSchemaLength);
+}
+
+int OpenAndroidContentFileDescriptor(const std::string_view uri,
+                                     const char* mode) {
+  if (!android_content_resolver_initialized_) {
+    return -1;
+  }
+  JNIEnv* jni_env = GetAndroidThreadJniEnv();
+  if (!jni_env) {
+    return -1;
+  }
+
+  jobject uri_object;
+  {
+    jstring uri_string;
+    {
+      std::u16string uri_u16 = xe::to_utf16(uri);
+      uri_string = jni_env->NewString(
+          reinterpret_cast<const jchar*>(uri_u16.data()), uri_u16.size());
+    }
+    if (!uri_string) {
+      return -1;
+    }
+    uri_object = jni_env->CallStaticObjectMethod(
+        android_uri_class_, android_uri_parse_, uri_string);
+    jni_env->DeleteLocalRef(uri_string);
+  }
+  if (!uri_object) {
+    return -1;
+  }
+
+  jstring mode_string = jni_env->NewStringUTF(mode);
+  if (!mode_string) {
+    jni_env->DeleteLocalRef(uri_object);
+    return -1;
+  }
+
+  jobject parcel_file_descriptor = jni_env->CallObjectMethod(
+      android_content_resolver_, android_content_resolver_open_file_descriptor_,
+      uri_object, mode_string);
+  jni_env->DeleteLocalRef(mode_string);
+  jni_env->DeleteLocalRef(uri_object);
+  if (jni_env->ExceptionCheck()) {
+    jni_env->ExceptionClear();
+    return -1;
+  }
+  if (!parcel_file_descriptor) {
+    return -1;
+  }
+  int file_descriptor = jni_env->CallIntMethod(
+      parcel_file_descriptor, android_parcel_file_descriptor_detach_fd_);
+  jni_env->DeleteLocalRef(parcel_file_descriptor);
+
+  return file_descriptor;
+}
+
+}  // namespace filesystem
+}  // namespace xe
diff --git a/src/xenia/base/main_android.cc b/src/xenia/base/main_android.cc
index eaa4642c3..5e43dbcad 100644
--- a/src/xenia/base/main_android.cc
+++ b/src/xenia/base/main_android.cc
@@ -16,6 +16,7 @@
 
 #include "xenia/base/assert.h"
 #include "xenia/base/cvar.h"
+#include "xenia/base/filesystem.h"
 #include "xenia/base/logging.h"
 #include "xenia/base/memory.h"
 #include "xenia/base/system.h"
@@ -98,6 +99,8 @@ void InitializeAndroidAppFromMainThread(int32_t api_level,
   // Logging uses threading.
   xe::threading::AndroidInitialize();
 
+  xe::filesystem::AndroidInitialize();
+
   // Initialize the cvars before logging.
   if (launch_arguments_bundle) {
     cvar::ParseLaunchArgumentsFromAndroidBundle(launch_arguments_bundle);
@@ -135,6 +138,8 @@ void ShutdownAndroidAppFromMainThread() {
 
   xe::ShutdownLogging();
 
+  xe::filesystem::AndroidShutdown();
+
   xe::threading::AndroidShutdown();
 
   if (android_application_context_) {