diff --git a/default.nix b/default.nix
index d85025fe..25808174 100644
--- a/default.nix
+++ b/default.nix
@@ -2,7 +2,7 @@ with import <nixpkgs> {};
 stdenv.mkDerivation {
     name = "visualboyadvance-m";
     buildInputs = if stdenv.isDarwin then
-        [ ninja cmake gcc nasm gettext pkg-config zip sfml zlib openal ffmpeg wxGTK32 SDL2 pcre pcre2 ]
+        [ ninja cmake gcc nasm gettext pkg-config zip sfml zlib openal ffmpeg wxGTK32 SDL2 pcre pcre2 darwin.apple_sdk.frameworks.IOKit darwin.apple_sdk.frameworks.Carbon darwin.apple_sdk.frameworks.Cocoa darwin.apple_sdk.frameworks.QuartzCore darwin.apple_sdk.frameworks.AudioToolbox darwin.apple_sdk.frameworks.OpenGL darwin.apple_sdk.frameworks.OpenAL ]
     else
         [ ninja cmake gcc nasm gettext pkg-config zip sfml zlib openal ffmpeg wxGTK32 mesa glfw SDL2 gtk3-x11 pcre pcre2 util-linuxMinimal libselinux libsepol libthai libdatrie xorg.libXdmcp xorg.libXtst libxkbcommon epoxy dbus at-spi2-core ];
 }
diff --git a/src/wx/CMakeLists.txt b/src/wx/CMakeLists.txt
index 8d936774..e9d39ef2 100644
--- a/src/wx/CMakeLists.txt
+++ b/src/wx/CMakeLists.txt
@@ -259,7 +259,7 @@ else()
 
     include_directories(${wxWidgets_INCLUDE_DIRS})
 
-    if(CMAKE_BUILD_TYPE MATCHES "^(Debug|RelWithDebInfo)$")
+    if(CMAKE_BUILD_TYPE STREQUAL Debug)
         # tell wx to enable debug mode if possible, if the cmake module did not do it for us
         execute_process(COMMAND "${wxWidgets_CONFIG_EXECUTABLE} --debug=yes" RESULT_VARIABLE WX_CONFIG_DEBUG OUTPUT_QUIET ERROR_QUIET)
 
@@ -279,6 +279,17 @@ else()
         add_compile_options(${CXX_COMPILE_FLAG})
     endforeach()
 
+    # Remove "-framework System" from libs on macOS, it's not necessary and nix doesn't have it.
+    if(APPLE)
+        unset(tmp_libs)
+        foreach(lib ${wxWidgets_LIBRARIES})
+            if(NOT lib STREQUAL "-framework System")
+                list(APPEND tmp_libs "${lib}")
+            endif()
+        endforeach()
+        set(wxWidgets_LIBRARIES "${tmp_libs}")
+    endif()
+
     # set up variables for some compile/run checks for wxWidgets
     set(CMAKE_REQUIRED_LIBRARIES ${CMAKE_REQUIRED_LIBRARIES} ${MY_CXX_FLAGS} ${MY_C_FLAGS} ${MY_CXX_LINKER_FLAGS} ${MY_C_LINKER_FLAGS} ${wxWidgets_LIBRARIES})
     set(CMAKE_REQUIRED_FLAGS ${CMAKE_REQUIRED_FLAGS} ${wxWidgets_CXX_FLAGS} ${MY_CXX_FLAGS} ${MY_C_FLAGS})