diff --git a/rpcs3/Emu/RSX/GL/GLGSRender.cpp b/rpcs3/Emu/RSX/GL/GLGSRender.cpp
index 7efb0a681e..ca1a1f4dba 100644
--- a/rpcs3/Emu/RSX/GL/GLGSRender.cpp
+++ b/rpcs3/Emu/RSX/GL/GLGSRender.cpp
@@ -38,7 +38,7 @@ GLGSRender::GLGSRender(utils::serial* ar) noexcept : GSRender(ar)
 {
 	m_shaders_cache = std::make_unique<gl::shader_cache>(m_prog_buffer, "opengl", "v1.94");
 
-	if (g_cfg.video.disable_vertex_cache || g_cfg.video.multithreaded_rsx)
+	if (g_cfg.video.disable_vertex_cache)
 		m_vertex_cache = std::make_unique<gl::null_vertex_cache>();
 	else
 		m_vertex_cache = std::make_unique<gl::weak_vertex_cache>();
diff --git a/rpcs3/Emu/RSX/VK/VKGSRender.cpp b/rpcs3/Emu/RSX/VK/VKGSRender.cpp
index 26e90075bf..1470c1e6e9 100644
--- a/rpcs3/Emu/RSX/VK/VKGSRender.cpp
+++ b/rpcs3/Emu/RSX/VK/VKGSRender.cpp
@@ -696,7 +696,7 @@ VKGSRender::VKGSRender(utils::serial* ar) noexcept : GSRender(ar)
 		}
 	);
 
-	if (g_cfg.video.disable_vertex_cache || g_cfg.video.multithreaded_rsx)
+	if (g_cfg.video.disable_vertex_cache)
 		m_vertex_cache = std::make_unique<vk::null_vertex_cache>();
 	else
 		m_vertex_cache = std::make_unique<vk::weak_vertex_cache>();
diff --git a/rpcs3/rpcs3qt/settings_dialog.cpp b/rpcs3/rpcs3qt/settings_dialog.cpp
index 5b2e4517b5..10b6883be2 100644
--- a/rpcs3/rpcs3qt/settings_dialog.cpp
+++ b/rpcs3/rpcs3qt/settings_dialog.cpp
@@ -648,11 +648,6 @@ settings_dialog::settings_dialog(std::shared_ptr<gui_settings> gui_settings, std
 
 	m_emu_settings->EnhanceCheckBox(ui->multithreadedRSX, emu_settings_type::MultithreadedRSX);
 	SubscribeTooltip(ui->multithreadedRSX, tooltips.settings.multithreaded_rsx);
-	connect(ui->multithreadedRSX, &QCheckBox::toggled, [this](bool checked)
-	{
-		ui->disableVertexCache->setEnabled(!checked);
-	});
-	ui->disableVertexCache->setEnabled(!ui->multithreadedRSX->isChecked());
 
 	m_emu_settings->EnhanceCheckBox(ui->strictModeRendering, emu_settings_type::StrictRenderingMode);
 	SubscribeTooltip(ui->strictModeRendering, tooltips.settings.strict_rendering_mode);