diff --git a/Source/Project64-core/N64System/Interpreter/InterpreterOps.cpp b/Source/Project64-core/N64System/Interpreter/InterpreterOps.cpp
index 6bf1bbac4..16562072b 100644
--- a/Source/Project64-core/N64System/Interpreter/InterpreterOps.cpp
+++ b/Source/Project64-core/N64System/Interpreter/InterpreterOps.cpp
@@ -94,6 +94,7 @@ void R4300iOp::ExecuteOps(uint32_t Cycles)
     int32_t & NextTimer = *g_NextTimer;
     bool CheckTimer = false;
     bool updateInstructionMemory = true;
+    m_InstructionRegion = -1;
 
     while (!Done && Cycles > 0)
     {