diff --git a/pcsx2/GS/Renderers/HW/GSRendererHW.cpp b/pcsx2/GS/Renderers/HW/GSRendererHW.cpp
index 00ea6058c3..78a142505a 100644
--- a/pcsx2/GS/Renderers/HW/GSRendererHW.cpp
+++ b/pcsx2/GS/Renderers/HW/GSRendererHW.cpp
@@ -1252,6 +1252,12 @@ void GSRendererHW::Draw()
 	GSDrawingContext* context = m_context;
 	const GSLocalMemory::psm_t& tex_psm = GSLocalMemory::m_psm[m_context->TEX0.PSM];
 
+	if (!context->FRAME.FBW)
+	{
+		GL_CACHE("Skipping draw with FRAME.FBW = 0.");
+		return;
+	}
+
 	// Fix TEX0 size
 	if (PRIM->TME && !IsMipMapActive())
 		m_context->ComputeFixedTEX0(m_vt.m_min.t.xyxy(m_vt.m_max.t));
@@ -1290,6 +1296,12 @@ void GSRendererHW::Draw()
 			(context->FRAME.FBP == context->ZBUF.ZBP && !PRIM->TME && zm == 0 && fm == 0 && context->TEST.ZTE)
 			);
 
+	if (no_rt && no_ds)
+	{
+		GL_CACHE("Skipping draw with no color nor depth output.");
+		return;
+	}
+
 	const bool draw_sprite_tex = PRIM->TME && (m_vt.m_primclass == GS_SPRITE_CLASS);
 	const GSVector4 delta_p = m_vt.m_max.p - m_vt.m_min.p;
 	const bool single_page = (delta_p.x <= 64.0f) && (delta_p.y <= 64.0f);