diff --git a/pcsx2-qt/MainWindow.cpp b/pcsx2-qt/MainWindow.cpp
index 54c7f63548..73b0f2e617 100644
--- a/pcsx2-qt/MainWindow.cpp
+++ b/pcsx2-qt/MainWindow.cpp
@@ -236,6 +236,7 @@ void MainWindow::setupAdditionalUi()
 	}
 
 	updateEmulationActions(false, false);
+	updateDisplayRelatedActions(false, false, false);
 }
 
 void MainWindow::connectSignals()
@@ -840,7 +841,6 @@ void MainWindow::updateEmulationActions(bool starting, bool running)
 
 	m_ui.actionSaveState->setEnabled(running);
 	m_ui.menuSaveState->setEnabled(running);
-	m_ui.menuWindowSize->setEnabled(starting_or_running);
 
 	m_ui.actionViewGameProperties->setEnabled(running);
 
@@ -854,6 +854,19 @@ void MainWindow::updateEmulationActions(bool starting, bool running)
 	m_ui.actionRescanAllGames->setDisabled(starting_or_running);
 }
 
+void MainWindow::updateDisplayRelatedActions(bool has_surface, bool render_to_main, bool fullscreen)
+{
+	// rendering to main, or switched to gamelist/grid
+	m_ui.actionViewSystemDisplay->setEnabled((has_surface && render_to_main) || (!has_surface && g_host_display));
+	m_ui.menuWindowSize->setEnabled(has_surface && !fullscreen);
+	m_ui.actionFullscreen->setEnabled(has_surface);
+
+	{
+		QSignalBlocker blocker(m_ui.actionFullscreen);
+		m_ui.actionFullscreen->setChecked(fullscreen);
+	}
+}
+
 void MainWindow::updateStatusBarWidgetVisibility()
 {
 	auto Update = [this](QWidget* widget, bool visible, int stretch) {
@@ -1791,8 +1804,6 @@ DisplayWidget* MainWindow::createDisplay(bool fullscreen, bool render_to_main)
 	updateWindowTitle();
 	updateWindowState();
 
-	m_ui.actionViewSystemDisplay->setEnabled(true);
-	m_ui.actionFullscreen->setEnabled(true);
 	m_ui.actionStartFullscreenUI->setEnabled(false);
 	m_ui.actionStartFullscreenUI2->setEnabled(false);
 
@@ -1886,8 +1897,6 @@ DisplayWidget* MainWindow::updateDisplay(bool fullscreen, bool render_to_main, b
 	m_display_widget->updateRelativeMode(s_vm_valid && !s_vm_paused);
 	m_display_widget->updateCursor(s_vm_valid && !s_vm_paused);
 
-	QSignalBlocker blocker(m_ui.actionFullscreen);
-	m_ui.actionFullscreen->setChecked(fullscreen);
 	return m_display_widget;
 }
 
@@ -1954,6 +1963,8 @@ void MainWindow::createDisplayWidget(bool fullscreen, bool render_to_main, bool
 		m_ui.mainContainer->setCurrentIndex(1);
 	}
 
+	updateDisplayRelatedActions(true, render_to_main, fullscreen);
+
 	// We need the surface visible.
 	QGuiApplication::sync();
 }
@@ -2039,6 +2050,8 @@ void MainWindow::destroyDisplayWidget(bool show_game_list)
 		m_display_container->deleteLater();
 		m_display_container = nullptr;
 	}
+
+	updateDisplayRelatedActions(false, false, false);
 }
 
 void MainWindow::focusDisplayWidget()
diff --git a/pcsx2-qt/MainWindow.h b/pcsx2-qt/MainWindow.h
index f63cb41890..60cd29dfe3 100644
--- a/pcsx2-qt/MainWindow.h
+++ b/pcsx2-qt/MainWindow.h
@@ -192,6 +192,7 @@ private:
 	void restoreStateFromConfig();
 
 	void updateEmulationActions(bool starting, bool running);
+	void updateDisplayRelatedActions(bool has_surface, bool render_to_main, bool fullscreen);
 	void updateStatusBarWidgetVisibility();
 	void updateWindowTitle();
 	void updateWindowState(bool force_visible = false);