diff --git a/pcsx2/x86/ix86-32/iR5900.cpp b/pcsx2/x86/ix86-32/iR5900.cpp
index 37057a289e..7e53c58dee 100644
--- a/pcsx2/x86/ix86-32/iR5900.cpp
+++ b/pcsx2/x86/ix86-32/iR5900.cpp
@@ -740,7 +740,12 @@ static void recExecute()
 void R5900::Dynarec::OpcodeImpl::recSYSCALL()
 {
 	EE::Profiler.EmitOp(eeOpcode::SYSCALL);
-
+	if (GPR_IS_CONST1(3))
+	{
+		// If it's FlushCache or iFlushCache, we can skip it since we don't support cache in the JIT.
+		if (g_cpuConstRegs[3].UC[0] == 0x64 || g_cpuConstRegs[3].UC[0] == 0x68)
+			return;
+	}
 	recCall(R5900::Interpreter::OpcodeImpl::SYSCALL);
 	g_branch = 2; // Indirect branch with event check.
 }