diff --git a/bin/resources/GameIndex.yaml b/bin/resources/GameIndex.yaml
index c297037726..6a121872c0 100644
--- a/bin/resources/GameIndex.yaml
+++ b/bin/resources/GameIndex.yaml
@@ -27095,6 +27095,7 @@ SLES-54962:
     autoFlush: 1 # Fixes bloom intensity.
     halfPixelOffset: 4 # Mostly aligns post processing.
     nativeScaling: 1 # Fixes post processing smoothness and position.
+    getSkipCount: "GSC_GuitarHero"
 SLES-54963:
   name: "Tony Hawk's Proving Ground"
   region: "PAL-E"
@@ -27142,6 +27143,7 @@ SLES-54974:
     autoFlush: 1 # Fixes bloom intensity.
     halfPixelOffset: 4 # Mostly aligns post processing.
     nativeScaling: 1 # Fixes post processing smoothness and position.
+    getSkipCount: "GSC_GuitarHero"
 SLES-54975:
   name: "George Of The Jungle"
   region: "PAL-E"
@@ -31234,6 +31236,7 @@ SLKA-25414:
     autoFlush: 1 # Fixes bloom intensity.
     halfPixelOffset: 4 # Mostly aligns post processing.
     nativeScaling: 1 # Fixes post processing smoothness and position.
+    getSkipCount: "GSC_GuitarHero"
 SLKA-25417:
   name: "Jin Samguk Mussang 4 - Empires"
   region: "NTSC-K"
@@ -59358,6 +59361,7 @@ SLPS-25840:
     autoFlush: 1 # Fixes bloom intensity.
     halfPixelOffset: 4 # Mostly aligns post processing.
     nativeScaling: 1 # Fixes post processing smoothness and position.
+    getSkipCount: "GSC_GuitarHero"
 SLPS-25841:
   name: "テイルズ オブ デスティニー ディレクターズカット [プレミアムBOX]"
   name-sort: "ているず おぶ ですてぃにー でぃれくたーずかっと [ぷれみあむBOX]"
@@ -59662,6 +59666,7 @@ SLPS-25890:
     autoFlush: 1 # Fixes bloom intensity.
     halfPixelOffset: 4 # Mostly aligns post processing.
     nativeScaling: 1 # Fixes post processing smoothness and position.
+    getSkipCount: "GSC_GuitarHero"
 SLPS-25891:
   name: "乃木坂春香の秘密 こすぷれ、はじめました♥ [限定版]"
   name-sort: "のぎざかはるかのひみつ こすぷれ はじめました [げんていばん]"
@@ -70174,6 +70179,7 @@ SLUS-21672:
     autoFlush: 1 # Fixes bloom intensity.
     halfPixelOffset: 4 # Mostly aligns post processing.
     nativeScaling: 1 # Fixes post processing smoothness and position.
+    getSkipCount: "GSC_GuitarHero"
 SLUS-21673:
   name: "College Hoops 2K8"
   region: "NTSC-U"
diff --git a/pcsx2/GS/Renderers/HW/GSHwHack.cpp b/pcsx2/GS/Renderers/HW/GSHwHack.cpp
index 19d57af186..de3ab04ef3 100644
--- a/pcsx2/GS/Renderers/HW/GSHwHack.cpp
+++ b/pcsx2/GS/Renderers/HW/GSHwHack.cpp
@@ -131,6 +131,22 @@ bool GSHwHack::GSC_SacredBlaze(GSRendererHW& r, int& skip)
 	return true;
 }
 
+bool GSHwHack::GSC_GuitarHero(GSRendererHW& r, int& skip)
+{
+	// Crowd sprite generation is a mess, better done in software.
+	if (skip == 0)
+	{
+		if (RTBW <= 4 && RTME && RFBW <= 4 && (r.m_context->TEX1.MMIN & 1) == 0)
+		{
+			r.ClearGSLocalMemory(r.m_context->offset.zb, r.m_r, 0);
+			r.SwPrimRender(r, RFBP != 0x2DC0, false);
+			skip = 1;
+		}
+	}
+
+	return true;
+}
+
 bool GSHwHack::GSC_SFEX3(GSRendererHW& r, int& skip)
 {
 	if (skip == 0)
@@ -1467,6 +1483,7 @@ const GSHwHack::Entry<GSRendererHW::GSC_Ptr> GSHwHack::s_get_skip_count_function
 	CRC_F(GSC_Manhunt2),
 	CRC_F(GSC_MidnightClub3),
 	CRC_F(GSC_SacredBlaze),
+	CRC_F(GSC_GuitarHero),
 	CRC_F(GSC_SakuraWarsSoLongMyLove),
 	CRC_F(GSC_Simple2000Vol114),
 	CRC_F(GSC_SFEX3),
diff --git a/pcsx2/GS/Renderers/HW/GSHwHack.h b/pcsx2/GS/Renderers/HW/GSHwHack.h
index 2da65232a1..6553bc44d1 100644
--- a/pcsx2/GS/Renderers/HW/GSHwHack.h
+++ b/pcsx2/GS/Renderers/HW/GSHwHack.h
@@ -10,6 +10,7 @@ public:
 	static bool GSC_GiTS(GSRendererHW& r, int& skip);
 	static bool GSC_Manhunt2(GSRendererHW& r, int& skip);
 	static bool GSC_SacredBlaze(GSRendererHW& r, int& skip);
+	static bool GSC_GuitarHero(GSRendererHW& r, int& skip);
 	static bool GSC_SFEX3(GSRendererHW& r, int& skip);
 	static bool GSC_Tekken5(GSRendererHW& r, int& skip);
 	static bool GSC_BurnoutGames(GSRendererHW& r, int& skip);