diff --git a/common/CMakeLists.txt b/common/CMakeLists.txt
index f679aaff7e..9796cce14a 100644
--- a/common/CMakeLists.txt
+++ b/common/CMakeLists.txt
@@ -127,6 +127,7 @@ target_sources(common PRIVATE
 	emitter/tools.h
 	emitter/x86emitter.h
 	emitter/x86types.h
+	Darwin/DarwinMisc.h
 )
 
 if(USE_VTUNE)
diff --git a/common/Darwin/DarwinMisc.cpp b/common/Darwin/DarwinMisc.cpp
index 4913a93718..9c0804b304 100644
--- a/common/Darwin/DarwinMisc.cpp
+++ b/common/Darwin/DarwinMisc.cpp
@@ -15,8 +15,11 @@
 
 #if defined(__APPLE__)
 
+#include "common/Darwin/DarwinMisc.h"
+
 #include <cstring>
 #include <cstdlib>
+#include <optional>
 #include <sys/types.h>
 #include <sys/sysctl.h>
 #include <time.h>
@@ -24,6 +27,7 @@
 #include <IOKit/pwr_mgt/IOPMLib.h>
 
 #include "common/Pcsx2Types.h"
+#include "common/Console.h"
 #include "common/General.h"
 #include "common/Threading.h"
 #include "common/WindowInfo.h"
@@ -89,6 +93,20 @@ static std::string sysctl_str(int category, int name)
 	return std::string(buf, len > 0 ? len - 1 : 0);
 }
 
+static std::optional<u32> sysctlbyname_u32(const char* name)
+{
+	u32 output;
+	size_t output_size = sizeof(output);
+	if (0 != sysctlbyname(name, &output, &output_size, nullptr, 0))
+		return std::nullopt;
+	if (output_size != sizeof(output))
+	{
+		DevCon.WriteLn("(DarwinMisc) sysctl %s gave unexpected size %zd", name, output_size);
+		return std::nullopt;
+	}
+	return output;
+}
+
 std::string GetOSVersionString()
 {
 	std::string type    = sysctl_str(CTL_KERN, KERN_OSTYPE);
@@ -135,4 +153,46 @@ void Threading::SleepUntil(u64 ticks)
 	nanosleep(&ts, nullptr);
 }
 
+std::vector<DarwinMisc::CPUClass> DarwinMisc::GetCPUClasses()
+{
+	std::vector<CPUClass> out;
+
+	if (std::optional<u32> nperflevels = sysctlbyname_u32("hw.nperflevels"))
+	{
+		char name[64];
+		for (u32 i = 0; i < *nperflevels; i++)
+		{
+			snprintf(name, sizeof(name), "hw.perflevel%u.physicalcpu", i);
+			std::optional<u32> physicalcpu = sysctlbyname_u32(name);
+			snprintf(name, sizeof(name), "hw.perflevel%u.logicalcpu", i);
+			std::optional<u32> logicalcpu = sysctlbyname_u32(name);
+
+			char levelname[64];
+			size_t levelname_size = sizeof(levelname);
+			snprintf(name, sizeof(name), "hw.perflevel%u.name", i);
+			if (0 != sysctlbyname(name, levelname, &levelname_size, nullptr, 0))
+				strcpy(levelname, "???");
+
+			if (!physicalcpu.has_value() || !logicalcpu.has_value())
+			{
+				Console.Warning("(DarwinMisc) Perf level %u is missing data on %s cpus!",
+				                i, !physicalcpu.has_value() ? "physical" : "logical");
+				continue;
+			}
+
+			out.push_back({levelname, *physicalcpu, *logicalcpu});
+		}
+	}
+	else if (std::optional<u32> physcpu = sysctlbyname_u32("hw.physicalcpu"))
+	{
+		out.push_back({"Default", *physcpu, sysctlbyname_u32("hw.logicalcpu").value_or(0)});
+	}
+	else
+	{
+		Console.Warning("(DarwinMisc) Couldn't get cpu core count!");
+	}
+
+	return out;
+}
+
 #endif
diff --git a/common/Darwin/DarwinMisc.h b/common/Darwin/DarwinMisc.h
new file mode 100644
index 0000000000..84d6f3c024
--- /dev/null
+++ b/common/Darwin/DarwinMisc.h
@@ -0,0 +1,36 @@
+/*  PCSX2 - PS2 Emulator for PCs
+ *  Copyright (C) 2023  PCSX2 Dev Team
+ *
+ *  PCSX2 is free software: you can redistribute it and/or modify it under the terms
+ *  of the GNU Lesser General Public License as published by the Free Software Found-
+ *  ation, either version 3 of the License, or (at your option) any later version.
+ *
+ *  PCSX2 is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY;
+ *  without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR
+ *  PURPOSE.  See the GNU General Public License for more details.
+ *
+ *  You should have received a copy of the GNU General Public License along with PCSX2.
+ *  If not, see <http://www.gnu.org/licenses/>.
+ */
+
+#pragma once
+#ifdef __APPLE__
+
+#include <string>
+#include <vector>
+
+#include "common/Pcsx2Types.h"
+
+namespace DarwinMisc {
+
+struct CPUClass {
+	std::string name;
+	u32 num_physical;
+	u32 num_logical;
+};
+
+std::vector<CPUClass> GetCPUClasses();
+
+}
+
+#endif
diff --git a/pcsx2/VMManager.cpp b/pcsx2/VMManager.cpp
index be48e24ec9..f7246c41b7 100644
--- a/pcsx2/VMManager.cpp
+++ b/pcsx2/VMManager.cpp
@@ -77,6 +77,10 @@
 #include <timeapi.h>
 #endif
 
+#ifdef __APPLE__
+#include "common/Darwin/DarwinMisc.h"
+#endif
+
 #ifdef ENABLE_DISCORD_PRESENCE
 #include "discord_rpc.h"
 #endif
@@ -2379,6 +2383,43 @@ static void SetMTVUAndAffinityControlDefault(SettingsInterface& si)
 	si.SetIntValue("EmuCore/GS", "extrathreads", extra_threads);
 }
 
+#elif defined(__APPLE__)
+
+static u32 s_big_cores;
+static u32 s_small_cores;
+
+static void InitializeCPUInfo()
+{
+	s_big_cores = 0;
+	s_small_cores = 0;
+	std::vector<DarwinMisc::CPUClass> classes = DarwinMisc::GetCPUClasses();
+	for (size_t i = 0; i < classes.size(); i++) {
+		const DarwinMisc::CPUClass& cls = classes[i];
+		const bool is_big = i == 0 || i < classes.size() - 1; // Assume only one group is small
+		DevCon.WriteLn("(VMManager) Found %u physical cores and %u logical cores in perf level %u (%s), assuming %s",
+		               cls.num_physical, cls.num_logical, i, cls.name.c_str(), is_big ? "big" : "small");
+		(is_big ? s_big_cores : s_small_cores) += cls.num_physical;
+	}
+}
+
+static void SetMTVUAndAffinityControlDefault(SettingsInterface& si)
+{
+	VMManager::EnsureCPUInfoInitialized();
+
+	Console.WriteLn("Detected %u big cores", s_big_cores);
+
+	if (s_big_cores >= 3)
+	{
+		Console.WriteLn("  So enabling MTVU.");
+		si.SetBoolValue("EmuCore/Speedhacks", "vuThread", true);
+	}
+	else
+	{
+		Console.WriteLn("  So disabling MTVU.");
+		si.SetBoolValue("EmuCore/Speedhacks", "vuThread", false);
+	}
+}
+
 #else
 
 static void InitializeCPUInfo()