diff --git a/pcsx2/GS/Renderers/HW/GSTextureCache.cpp b/pcsx2/GS/Renderers/HW/GSTextureCache.cpp
index b0c97df0f2..a80342499d 100644
--- a/pcsx2/GS/Renderers/HW/GSTextureCache.cpp
+++ b/pcsx2/GS/Renderers/HW/GSTextureCache.cpp
@@ -3626,7 +3626,8 @@ bool GSTextureCache::Move(u32 SBP, u32 SBW, u32 SPSM, int sx, int sy, u32 DBP, u
 	// DX11/12 is a bit lame and can't partial copy depth targets. We could do this with a blit instead,
 	// but so far haven't seen anything which needs it.
 	const GSRendererType renderer = GSGetCurrentRenderer();
-	if (renderer == GSRendererType::DX11 || renderer == GSRendererType::DX12)
+	const bool renderer_is_directx = (renderer == GSRendererType::DX11 || renderer == GSRendererType::DX12);
+	if (renderer_is_directx)
 	{
 		if (spsm_s.depth || dpsm_s.depth)
 			return false;
@@ -3744,7 +3745,8 @@ bool GSTextureCache::Move(u32 SBP, u32 SBW, u32 SPSM, int sx, int sy, u32 DBP, u
 	}
 
 	// If the copies overlap, this is a validation error, so we need to copy to a temporary texture first.
-	if ((SBP == DBP) && !(GSVector4i(sx, sy, sx + w, sy + h).rintersect(GSVector4i(dx, dy, dx + w, dy + h))).rempty())
+	// DirectX also can't copy to the same texture it's reading from (except potentially with enhanced barriers).
+	if (SBP == DBP && (!(GSVector4i(sx, sy, sx + w, sy + h).rintersect(GSVector4i(dx, dy, dx + w, dy + h))).rempty() || renderer_is_directx))
 	{
 		GSTexture* tmp_texture = src->m_texture->IsDepthStencil() ?
 									 g_gs_device->CreateDepthStencil(src->m_texture->GetWidth(), src->m_texture->GetHeight(), src->m_texture->GetFormat(), false) :