diff --git a/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.cpp b/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.cpp
index 3d199351be..2922d08ef8 100644
--- a/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.cpp
+++ b/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.cpp
@@ -77,6 +77,7 @@ QWidget* SymbolTreeValueDelegate::createEditor(QWidget* parent, const QStyleOpti
 					{
 						QCheckBox* editor = new QCheckBox(parent);
 						editor->setChecked(value.toBool());
+						connect(editor, &QCheckBox::checkStateChanged, this, &SymbolTreeValueDelegate::onCheckBoxStateChanged);
 						result = editor;
 
 						break;
@@ -276,6 +277,13 @@ void SymbolTreeValueDelegate::setModelData(QWidget* editor, QAbstractItemModel*
 		model->setData(index, value, SymbolTreeModel::EDIT_ROLE);
 }
 
+void SymbolTreeValueDelegate::onCheckBoxStateChanged(Qt::CheckState state)
+{
+	QCheckBox* check_box = qobject_cast<QCheckBox*>(sender());
+	if (check_box)
+		commitData(check_box);
+}
+
 void SymbolTreeValueDelegate::onComboBoxIndexChanged(int index)
 {
 	QComboBox* combo_box = qobject_cast<QComboBox*>(sender());
diff --git a/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.h b/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.h
index 934727fe73..03028297c5 100644
--- a/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.h
+++ b/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.h
@@ -21,8 +21,10 @@ public:
 	void setModelData(QWidget* editor, QAbstractItemModel* model, const QModelIndex& index) const override;
 
 protected:
-	// Without this, setModelData would only be called when a combo box was
-	// deselected rather than when an option was picked.
+	// These make it so the values inputted are written back to memory
+	// immediately when the widgets are interacted with rather than when they
+	// are deselected.
+	void onCheckBoxStateChanged(Qt::CheckState state);
 	void onComboBoxIndexChanged(int index);
 
 	DebugInterface& m_cpu;