diff --git a/pcsx2/GS/GS.cpp b/pcsx2/GS/GS.cpp
index 4c79689365..aa785b1b2a 100644
--- a/pcsx2/GS/GS.cpp
+++ b/pcsx2/GS/GS.cpp
@@ -285,6 +285,7 @@ static bool DoGSOpen(GSRendererType renderer, u8* basemem)
 	GSConfig.OsdShowGPU = EmuConfig.GS.OsdShowGPU && display->SetGPUTimingEnabled(true);
 
 	g_gs_renderer->SetRegsMem(basemem);
+	g_perfmon.Reset();
 	return true;
 }
 
diff --git a/pcsx2/GS/GSPerfMon.cpp b/pcsx2/GS/GSPerfMon.cpp
index 276d92904d..13c17260d9 100644
--- a/pcsx2/GS/GSPerfMon.cpp
+++ b/pcsx2/GS/GSPerfMon.cpp
@@ -19,13 +19,15 @@
 
 GSPerfMon g_perfmon;
 
-GSPerfMon::GSPerfMon()
-	: m_frame(0)
-	, m_lastframe(0)
-	, m_count(0)
+GSPerfMon::GSPerfMon() = default;
+
+void GSPerfMon::Reset()
 {
-	memset(m_counters, 0, sizeof(m_counters));
-	memset(m_stats, 0, sizeof(m_stats));
+	m_frame = 0;
+	m_lastframe = 0;
+	m_count = 0;
+	std::memset(m_counters, 0, sizeof(m_counters));
+	std::memset(m_stats, 0, sizeof(m_stats));
 }
 
 void GSPerfMon::EndFrame()
diff --git a/pcsx2/GS/GSPerfMon.h b/pcsx2/GS/GSPerfMon.h
index 5091de8211..0dbfd6e838 100644
--- a/pcsx2/GS/GSPerfMon.h
+++ b/pcsx2/GS/GSPerfMon.h
@@ -38,16 +38,18 @@ public:
 	};
 
 protected:
-	double m_counters[CounterLast];
-	double m_stats[CounterLast];
-	u64 m_frame;
-	clock_t m_lastframe;
-	int m_count;
-	int m_disp_fb_sprite_blits;
+	double m_counters[CounterLast] = {};
+	double m_stats[CounterLast] = {};
+	u64 m_frame = 0;
+	clock_t m_lastframe = 0;
+	int m_count = 0;
+	int m_disp_fb_sprite_blits = 0;
 
 public:
 	GSPerfMon();
 
+	void Reset();
+
 	void SetFrame(u64 frame) { m_frame = frame; }
 	u64 GetFrame() { return m_frame; }
 	void EndFrame();