diff --git a/pcsx2/GS/GS.cpp b/pcsx2/GS/GS.cpp
index 52988abc00..c6e55a681c 100644
--- a/pcsx2/GS/GS.cpp
+++ b/pcsx2/GS/GS.cpp
@@ -1368,7 +1368,6 @@ void GSApp::Init()
 	m_default_configuration["MaxAnisotropy"]                              = "0";
 	m_default_configuration["mipmap"]                                     = "1";
 	m_default_configuration["mipmap_hw"]                                  = std::to_string(static_cast<int>(HWMipmapLevel::Automatic));
-	m_default_configuration["NTSC_Saturation"]                            = "1";
 	m_default_configuration["OsdShowMessages"]                            = "1";
 	m_default_configuration["OsdShowSpeed"]                               = "0";
 	m_default_configuration["OsdShowFPS"]                                 = "0";
diff --git a/pcsx2/GS/GSState.cpp b/pcsx2/GS/GSState.cpp
index 326f036bc2..c2e16b78fd 100644
--- a/pcsx2/GS/GSState.cpp
+++ b/pcsx2/GS/GSState.cpp
@@ -52,7 +52,6 @@ GSState::GSState()
 	// Let's keep it disabled to ease debug.
 	m_nativeres = GSConfig.UpscaleMultiplier == 1;
 	m_mipmap = GSConfig.Mipmap;
-	m_NTSC_Saturation = theApp.GetConfigB("NTSC_Saturation");
 
 	s_n = 0;
 	s_dump = theApp.GetConfigB("dump");
diff --git a/pcsx2/GS/GSState.h b/pcsx2/GS/GSState.h
index abe655241a..ce147db65b 100644
--- a/pcsx2/GS/GSState.h
+++ b/pcsx2/GS/GSState.h
@@ -231,7 +231,6 @@ public:
 	std::unique_ptr<GSDumpBase> m_dump;
 	int m_options;
 	int m_frameskip;
-	bool m_NTSC_Saturation;
 	bool m_nativeres;
 	bool m_mipmap;
 	bool m_primflush;