diff --git a/bin/resources/GameIndex.yaml b/bin/resources/GameIndex.yaml
index d460073cc5..458f5173f6 100644
--- a/bin/resources/GameIndex.yaml
+++ b/bin/resources/GameIndex.yaml
@@ -19399,6 +19399,11 @@ SLES-54384:
 SLES-54385:
   name: "Atelier Iris 2 - The Azoth of Destiny"
   region: "PAL-E"
+  gameFixes:
+    - SoftwareRendererFMVHack # Flickering in FMV.
+  gsHWFixes:
+    roundSprite: 1 # Fixes font artifacts for health and other sprites.
+    texturePreloading: 0 # Improves performance and prevents it disabling itself regardless.
 SLES-54388:
   name: "Kim Possible - What's the Switch"
   region: "PAL-M3"
@@ -30260,6 +30265,11 @@ SLPM-65984:
 SLPM-65985:
   name: "Iris no Atelier - Eternal Mana 2"
   region: "NTSC-J"
+  gameFixes:
+    - SoftwareRendererFMVHack # Flickering in FMV.
+  gsHWFixes:
+    roundSprite: 1 # Fixes font artifacts for health and other sprites.
+    texturePreloading: 0 # Improves performance and prevents it disabling itself regardless.
 SLPM-65986:
   name: "Quartett! The Stage of Love [Limited Edition]"
   region: "NTSC-J"
@@ -31902,6 +31912,8 @@ SLPM-66436:
   name: "Iris no Atelier - Grand Fantasm"
   region: "NTSC-J"
   compat: 5
+  gsHWFixes:
+    roundSprite: 1 # Fixes vertical lines in FMVs, character portraits and other sprites.
 SLPM-66437:
   name: "Soul Link Extension"
   region: "NTSC-J"
@@ -32315,6 +32327,11 @@ SLPM-66536:
 SLPM-66537:
   name: "Iris no Atelier - Eternal Mana 2 [Gust Best Price]"
   region: "NTSC-J"
+  gameFixes:
+    - SoftwareRendererFMVHack # Flickering in FMV.
+  gsHWFixes:
+    roundSprite: 1 # Fixes font artifacts for health and other sprites.
+    texturePreloading: 0 # Improves performance and prevents it disabling itself regardless.
 SLPM-66538:
   name: "GI Jockey 4 2006"
   region: "NTSC-J"
@@ -33462,6 +33479,8 @@ SLPM-66848:
 SLPM-66849:
   name: "Iris no Atelier - Grand Fantasm [Gust Best Price]"
   region: "NTSC-J"
+  gsHWFixes:
+    roundSprite: 1 # Fixes vertical lines in FMVs, character portraits and other sprites.
 SLPM-66850:
   name: "Arcana Heart"
   region: "NTSC-J"
@@ -46158,6 +46177,11 @@ SLUS-21327:
   name: "Atelier Iris 2 - The Azoth of Destiny"
   region: "NTSC-U"
   compat: 5
+  gameFixes:
+    - SoftwareRendererFMVHack # Flickering in FMV.
+  gsHWFixes:
+    roundSprite: 1 # Fixes font artifacts for health and other sprites.
+    texturePreloading: 0 # Improves performance and prevents it disabling itself regardless.
 SLUS-21328:
   name: "Pac-Man World Rally"
   region: "NTSC-U"