diff --git a/pcsx2/GS/Renderers/Common/GSDevice.cpp b/pcsx2/GS/Renderers/Common/GSDevice.cpp
index 2a49f3d8e7..f4a6d93053 100644
--- a/pcsx2/GS/Renderers/Common/GSDevice.cpp
+++ b/pcsx2/GS/Renderers/Common/GSDevice.cpp
@@ -103,7 +103,7 @@ void GSDevice::RestoreAPIState()
 {
 }
 
-GSTexture* GSDevice::FetchSurface(GSTexture::Type type, int w, int h, GSTexture::Format format)
+GSTexture* GSDevice::FetchSurface(GSTexture::Type type, int w, int h, GSTexture::Format format, bool clear)
 {
 	const GSVector2i size(w, h);
 
@@ -135,10 +135,20 @@ GSTexture* GSDevice::FetchSurface(GSTexture::Type type, int w, int h, GSTexture:
 	switch (type)
 	{
 	case GSTexture::Type::RenderTarget:
-		ClearRenderTarget(t, 0);
+		{
+			if (clear)
+				ClearRenderTarget(t, 0);
+			else
+				InvalidateRenderTarget(t);
+		}
 		break;
 	case GSTexture::Type::DepthStencil:
-		ClearDepth(t);
+		{
+			if (clear)
+				ClearDepth(t);
+			else
+				InvalidateRenderTarget(t);
+		}
 		break;
 	default:
 		break;
@@ -212,34 +222,34 @@ void GSDevice::PurgePool()
 	m_pool.clear();
 }
 
-GSTexture* GSDevice::CreateSparseRenderTarget(int w, int h, GSTexture::Format format)
+GSTexture* GSDevice::CreateSparseRenderTarget(int w, int h, GSTexture::Format format, bool clear)
 {
-	return FetchSurface(HasColorSparse() ? GSTexture::Type::SparseRenderTarget : GSTexture::Type::RenderTarget, w, h, format);
+	return FetchSurface(HasColorSparse() ? GSTexture::Type::SparseRenderTarget : GSTexture::Type::RenderTarget, w, h, format, clear);
 }
 
-GSTexture* GSDevice::CreateSparseDepthStencil(int w, int h, GSTexture::Format format)
+GSTexture* GSDevice::CreateSparseDepthStencil(int w, int h, GSTexture::Format format, bool clear)
 {
-	return FetchSurface(HasDepthSparse() ? GSTexture::Type::SparseDepthStencil : GSTexture::Type::DepthStencil, w, h, format);
+	return FetchSurface(HasDepthSparse() ? GSTexture::Type::SparseDepthStencil : GSTexture::Type::DepthStencil, w, h, format, clear);
 }
 
-GSTexture* GSDevice::CreateRenderTarget(int w, int h, GSTexture::Format format)
+GSTexture* GSDevice::CreateRenderTarget(int w, int h, GSTexture::Format format, bool clear)
 {
-	return FetchSurface(GSTexture::Type::RenderTarget, w, h, format);
+	return FetchSurface(GSTexture::Type::RenderTarget, w, h, format, clear);
 }
 
-GSTexture* GSDevice::CreateDepthStencil(int w, int h, GSTexture::Format format)
+GSTexture* GSDevice::CreateDepthStencil(int w, int h, GSTexture::Format format, bool clear)
 {
-	return FetchSurface(GSTexture::Type::DepthStencil, w, h, format);
+	return FetchSurface(GSTexture::Type::DepthStencil, w, h, format, clear);
 }
 
 GSTexture* GSDevice::CreateTexture(int w, int h, GSTexture::Format format)
 {
-	return FetchSurface(GSTexture::Type::Texture, w, h, format);
+	return FetchSurface(GSTexture::Type::Texture, w, h, format, false);
 }
 
 GSTexture* GSDevice::CreateOffscreen(int w, int h, GSTexture::Format format)
 {
-	return FetchSurface(GSTexture::Type::Offscreen, w, h, format);
+	return FetchSurface(GSTexture::Type::Offscreen, w, h, format, false);
 }
 
 GSTexture::Format GSDevice::GetDefaultTextureFormat(GSTexture::Type type)
@@ -387,7 +397,7 @@ void GSDevice::ShadeBoost()
 	}
 }
 
-bool GSDevice::ResizeTexture(GSTexture** t, GSTexture::Type type, int w, int h)
+bool GSDevice::ResizeTexture(GSTexture** t, GSTexture::Type type, int w, int h, bool clear)
 {
 	if (t == NULL)
 	{
@@ -402,7 +412,7 @@ bool GSDevice::ResizeTexture(GSTexture** t, GSTexture::Type type, int w, int h)
 		GSTexture::Format fmt = t2 ? t2->GetFormat() : GetDefaultTextureFormat(type);
 		delete t2;
 
-		t2 = FetchSurface(type, w, h, fmt);
+		t2 = FetchSurface(type, w, h, fmt, clear);
 
 		*t = t2;
 	}
@@ -410,9 +420,9 @@ bool GSDevice::ResizeTexture(GSTexture** t, GSTexture::Type type, int w, int h)
 	return t2 != NULL;
 }
 
-bool GSDevice::ResizeTexture(GSTexture** t, int w, int h)
+bool GSDevice::ResizeTexture(GSTexture** t, int w, int h, bool clear)
 {
-	return ResizeTexture(t, GSTexture::Type::Texture, w, h);
+	return ResizeTexture(t, GSTexture::Type::Texture, w, h, clear);
 }
 
 bool GSDevice::ResizeTarget(GSTexture** t, int w, int h)
diff --git a/pcsx2/GS/Renderers/Common/GSDevice.h b/pcsx2/GS/Renderers/Common/GSDevice.h
index 4aacfcb187..f64b97387b 100644
--- a/pcsx2/GS/Renderers/Common/GSDevice.h
+++ b/pcsx2/GS/Renderers/Common/GSDevice.h
@@ -546,7 +546,7 @@ protected:
 	FeatureSupport m_features;
 
 	virtual GSTexture* CreateSurface(GSTexture::Type type, int w, int h, GSTexture::Format format) = 0;
-	virtual GSTexture* FetchSurface(GSTexture::Type type, int w, int h, GSTexture::Format format);
+	virtual GSTexture* FetchSurface(GSTexture::Type type, int w, int h, GSTexture::Format format, bool clear);
 
 	virtual void DoMerge(GSTexture* sTex[3], GSVector4* sRect, GSTexture* dTex, GSVector4* dRect, const GSRegPMODE& PMODE, const GSRegEXTBUF& EXTBUF, const GSVector4& c) = 0;
 	virtual void DoInterlace(GSTexture* sTex, GSTexture* dTex, int shader, bool linear, float yoffset) = 0;
@@ -584,13 +584,14 @@ public:
 
 	virtual void ClearRenderTarget(GSTexture* t, const GSVector4& c) {}
 	virtual void ClearRenderTarget(GSTexture* t, u32 c) {}
+	virtual void InvalidateRenderTarget(GSTexture* t) {}
 	virtual void ClearDepth(GSTexture* t) {}
 	virtual void ClearStencil(GSTexture* t, u8 c) {}
 
-	GSTexture* CreateSparseRenderTarget(int w, int h, GSTexture::Format format);
-	GSTexture* CreateSparseDepthStencil(int w, int h, GSTexture::Format format);
-	GSTexture* CreateRenderTarget(int w, int h, GSTexture::Format format);
-	GSTexture* CreateDepthStencil(int w, int h, GSTexture::Format format);
+	GSTexture* CreateSparseRenderTarget(int w, int h, GSTexture::Format format, bool clear = true);
+	GSTexture* CreateSparseDepthStencil(int w, int h, GSTexture::Format format, bool clear = true);
+	GSTexture* CreateRenderTarget(int w, int h, GSTexture::Format format, bool clear = true);
+	GSTexture* CreateDepthStencil(int w, int h, GSTexture::Format format, bool clear = true);
 	GSTexture* CreateTexture(int w, int h, GSTexture::Format format);
 	GSTexture* CreateOffscreen(int w, int h, GSTexture::Format format);
 	GSTexture::Format GetDefaultTextureFormat(GSTexture::Type type);
@@ -623,8 +624,8 @@ public:
 	void ShadeBoost();
 	void ExternalFX();
 
-	bool ResizeTexture(GSTexture** t, GSTexture::Type type, int w, int h);
-	bool ResizeTexture(GSTexture** t, int w, int h);
+	bool ResizeTexture(GSTexture** t, GSTexture::Type type, int w, int h, bool clear = true);
+	bool ResizeTexture(GSTexture** t, int w, int h, bool clear = true);
 	bool ResizeTarget(GSTexture** t, int w, int h);
 	bool ResizeTarget(GSTexture** t);
 
diff --git a/pcsx2/GS/Renderers/HW/GSTextureCache.cpp b/pcsx2/GS/Renderers/HW/GSTextureCache.cpp
index 670579a2cb..dbc6a4f195 100644
--- a/pcsx2/GS/Renderers/HW/GSTextureCache.cpp
+++ b/pcsx2/GS/Renderers/HW/GSTextureCache.cpp
@@ -1297,7 +1297,7 @@ GSTextureCache::Source* GSTextureCache::CreateSource(const GIFRegTEX0& TEX0, con
 		int h = (int)(scale.y * th);
 
 		GSTexture* sTex = dst->m_texture;
-		GSTexture* dTex = g_gs_device->CreateRenderTarget(w, h, GSTexture::Format::Color);
+		GSTexture* dTex = g_gs_device->CreateTexture(w, h, GSTexture::Format::Color);
 
 		GSVector4i area(x, y, x + w, y + h);
 		g_gs_device->CopyRect(sTex, dTex, area);
@@ -1329,7 +1329,7 @@ GSTextureCache::Source* GSTextureCache::CreateSource(const GIFRegTEX0& TEX0, con
 		// So it could be tricky to put in the middle of the DrawPrims
 
 		// Texture is created to keep code compatibility
-		GSTexture* dTex = g_gs_device->CreateRenderTarget(tw, th, GSTexture::Format::Color);
+		GSTexture* dTex = g_gs_device->CreateTexture(tw, th, GSTexture::Format::Color);
 
 		// Keep a trace of origin of the texture
 		src->m_texture = dTex;
@@ -1496,11 +1496,15 @@ GSTextureCache::Source* GSTextureCache::CreateSource(const GIFRegTEX0& TEX0, con
 		}
 
 		GSVector4 sRect(0, 0, w, h);
+		const bool texture_completely_overwritten = ((sRect == dRect).alltrue());
+		const bool use_texture = (texture_completely_overwritten && shader == ShaderConvert::COPY);
 
 		// Don't be fooled by the name. 'dst' is the old target (hence the input)
 		// 'src' is the new texture cache entry (hence the output)
 		GSTexture* sTex = dst->m_texture;
-		GSTexture* dTex = g_gs_device->CreateRenderTarget(w, h, GSTexture::Format::Color);
+		GSTexture* dTex = use_texture ?
+			g_gs_device->CreateTexture(w, h, GSTexture::Format::Color) :
+			g_gs_device->CreateRenderTarget(w, h, GSTexture::Format::Color, !texture_completely_overwritten);
 		src->m_texture = dTex;
 
 		// GH: by default (m_paltex == 0) GS converts texture to the 32 bit format
@@ -1536,7 +1540,7 @@ GSTextureCache::Source* GSTextureCache::CreateSource(const GIFRegTEX0& TEX0, con
 		// copy. Likely a speed boost and memory usage reduction.
 		bool linear = (TEX0.PSM == PSM_PSMCT32 || TEX0.PSM == PSM_PSMCT24);
 
-		if ((sRect == dRect).alltrue() && shader == ShaderConvert::COPY)
+		if (use_texture)
 		{
 			if (half_right)
 			{
diff --git a/pcsx2/GS/Renderers/OpenGL/GSDeviceOGL.cpp b/pcsx2/GS/Renderers/OpenGL/GSDeviceOGL.cpp
index 9d1280e068..7e73dd8e68 100644
--- a/pcsx2/GS/Renderers/OpenGL/GSDeviceOGL.cpp
+++ b/pcsx2/GS/Renderers/OpenGL/GSDeviceOGL.cpp
@@ -752,6 +752,31 @@ void GSDeviceOGL::ClearRenderTarget(GSTexture* t, u32 c)
 	ClearRenderTarget(t, color);
 }
 
+void GSDeviceOGL::InvalidateRenderTarget(GSTexture* t)
+{
+	GSTextureOGL* T = static_cast<GSTextureOGL*>(t);
+	if (!T || T->HasBeenCleaned())
+		return;
+
+	if (GLAD_GL_VERSION_4_3 || GLAD_GL_ES_VERSION_3_0)
+	{
+		OMSetFBO(m_fbo);
+
+		if (T->GetType() == GSTexture::Type::DepthStencil || T->GetType() == GSTexture::Type::SparseDepthStencil)
+		{
+			OMAttachDs(T);
+			const GLenum attachments[] = {GL_DEPTH_STENCIL_ATTACHMENT};
+			glInvalidateFramebuffer(GL_DRAW_FRAMEBUFFER, std::size(attachments), attachments);
+		}
+		else
+		{
+			OMAttachRt(T);
+			const GLenum attachments[] = {GL_COLOR_ATTACHMENT0};
+			glInvalidateFramebuffer(GL_DRAW_FRAMEBUFFER, std::size(attachments), attachments);
+		}
+	}
+}
+
 void GSDeviceOGL::ClearDepth(GSTexture* t)
 {
 	if (!t)
diff --git a/pcsx2/GS/Renderers/OpenGL/GSDeviceOGL.h b/pcsx2/GS/Renderers/OpenGL/GSDeviceOGL.h
index f10e893190..3b3a2cab7f 100644
--- a/pcsx2/GS/Renderers/OpenGL/GSDeviceOGL.h
+++ b/pcsx2/GS/Renderers/OpenGL/GSDeviceOGL.h
@@ -336,6 +336,7 @@ public:
 
 	void ClearRenderTarget(GSTexture* t, const GSVector4& c) final;
 	void ClearRenderTarget(GSTexture* t, u32 c) final;
+	void InvalidateRenderTarget(GSTexture* t) final;
 	void ClearDepth(GSTexture* t) final;
 	void ClearStencil(GSTexture* t, u8 c) final;
 
diff --git a/pcsx2/GS/Renderers/SW/GSRendererSW.cpp b/pcsx2/GS/Renderers/SW/GSRendererSW.cpp
index 77cb0880cf..ba55af5176 100644
--- a/pcsx2/GS/Renderers/SW/GSRendererSW.cpp
+++ b/pcsx2/GS/Renderers/SW/GSRendererSW.cpp
@@ -146,7 +146,7 @@ GSTexture* GSRendererSW::GetOutput(int i, int& y_offset)
 
 	// TODO: round up bottom
 
-	if (g_gs_device->ResizeTexture(&m_texture[i], w, h))
+	if (g_gs_device->ResizeTexture(&m_texture[i], w, h, false))
 	{
 		static int pitch = 1024 * 4;