diff --git a/pcsx2-qt/GameList/GameListModel.cpp b/pcsx2-qt/GameList/GameListModel.cpp
index 075199a0f6..595f7c7894 100644
--- a/pcsx2-qt/GameList/GameListModel.cpp
+++ b/pcsx2-qt/GameList/GameListModel.cpp
@@ -438,7 +438,7 @@ bool GameListModel::titlesLessThan(int left_row, int right_row) const
 
 	const GameList::Entry* left = GameList::GetEntryByIndex(left_row);
 	const GameList::Entry* right = GameList::GetEntryByIndex(right_row);
-	return (StringUtil::Strcasecmp(left->GetTitleSort().c_str(), right->GetTitleSort().c_str()) < 0);
+	return QtHost::LocaleSensitiveCompare(QString::fromStdString(left->GetTitleSort()), QString::fromStdString(right->GetTitleSort())) < 0;
 }
 
 bool GameListModel::lessThan(const QModelIndex& left_index, const QModelIndex& right_index, int column) const
diff --git a/pcsx2-qt/QtHost.h b/pcsx2-qt/QtHost.h
index 959ba3df59..5f88aaafdd 100644
--- a/pcsx2-qt/QtHost.h
+++ b/pcsx2-qt/QtHost.h
@@ -283,4 +283,7 @@ namespace QtHost
 	/// VM state, safe to access on UI thread.
 	bool IsVMValid();
 	bool IsVMPaused();
+
+	/// Compare strings in the locale of the current UI language
+	int LocaleSensitiveCompare(QStringView lhs, QStringView rhs);
 } // namespace QtHost
diff --git a/pcsx2-qt/Translations.cpp b/pcsx2-qt/Translations.cpp
index f2599b42f2..8b949ec6ed 100644
--- a/pcsx2-qt/Translations.cpp
+++ b/pcsx2-qt/Translations.cpp
@@ -66,6 +66,9 @@ namespace QtHost
 	static const GlyphInfo* GetGlyphInfo(const std::string_view& language);
 
 	static std::vector<ImWchar> s_glyph_ranges;
+
+	static QLocale s_current_locale;
+	static QCollator s_current_collator;
 } // namespace QtHost
 
 static std::vector<QTranslator*> s_translators;
@@ -112,6 +115,11 @@ void QtHost::InstallTranslator()
 	if (language == QStringLiteral("system"))
 		language = getSystemLanguage();
 
+	QString qlanguage = language;
+	qlanguage.replace('-', '_');
+	s_current_locale = QLocale(qlanguage);
+	s_current_collator = QCollator(s_current_locale);
+
 	// Install the base qt translation first.
 #ifdef __APPLE__
 	const QString base_dir = QStringLiteral("%1/../Resources/translations").arg(qApp->applicationDirPath());
@@ -375,3 +383,8 @@ const QtHost::GlyphInfo* QtHost::GetGlyphInfo(const std::string_view& language)
 
 	return nullptr;
 }
+
+int QtHost::LocaleSensitiveCompare(QStringView lhs, QStringView rhs)
+{
+	return s_current_collator.compare(lhs, rhs);
+}