diff --git a/pcsx2/DebugTools/DebugInterface.cpp b/pcsx2/DebugTools/DebugInterface.cpp
index 8ff13655a1..d139aca6f3 100644
--- a/pcsx2/DebugTools/DebugInterface.cpp
+++ b/pcsx2/DebugTools/DebugInterface.cpp
@@ -206,22 +206,31 @@ bool DebugInterface::parseExpression(PostfixExpression& exp, u64& dest)
 
 u32 R5900DebugInterface::read8(u32 address)
 {
+	if (!isValidAddress(address))
+		return -1;
+
 	return memRead8(address);
 }
 
 u32 R5900DebugInterface::read16(u32 address)
 {
+	if (!isValidAddress(address) || address % 2)
+		return -1;
+
 	return memRead16(address);
 }
 
 u32 R5900DebugInterface::read32(u32 address)
 {
+	if (!isValidAddress(address) || address % 4)
+		return -1;
+
 	return memRead32(address);
 }
 
 u64 R5900DebugInterface::read64(u32 address)
 {
-	if (!isValidAddress(address))
+	if (!isValidAddress(address) || address % 8)
 		return -1;
 
 	u64 result;
@@ -231,10 +240,13 @@ u64 R5900DebugInterface::read64(u32 address)
 
 u128 R5900DebugInterface::read128(u32 address)
 {
-	if (!isValidAddress(address))
-		return u128::From32(-1);
-
 	__aligned16 u128 result;
+	if (!isValidAddress(address) || address % 16)
+	{
+		result.hi = result.lo = -1;
+		return result;
+	}
+
 	memRead128(address,result);
 	return result;
 }
diff --git a/pcsx2/DebugTools/MIPSAnalyst.cpp b/pcsx2/DebugTools/MIPSAnalyst.cpp
index 964b2edc61..2da49cee1f 100644
--- a/pcsx2/DebugTools/MIPSAnalyst.cpp
+++ b/pcsx2/DebugTools/MIPSAnalyst.cpp
@@ -317,26 +317,35 @@ namespace MIPSAnalyst
 			size = 2;
 			break;
 		case 0x23:		// lw
-		case 0x26:		// lwr
 		case 0x2B:		// sw
+			size = 4;
+			break;
+		case 0x26:		// lwr
 		case 0x2E:		// swr
 			size = 4;
+			info.lrType = LOADSTORE_RIGHT; 
 			break;
 		case 0x22:		// lwl
 		case 0x2A:		// swl
 			size = 4;
 			off = -3;
+			info.lrType = LOADSTORE_LEFT; 
 			break;
 		case 0x37:		// ld
-		case 0x1B:		// ldr
 		case 0x3F:		// sd
+			size = 8;
+			break;
+		case 0x1B:		// ldr
 		case 0x2D:		// sdr
 			size = 8;
+			info.lrType = LOADSTORE_RIGHT; 
 			break;
 		case 0x1A:		// ldl
 		case 0x2C:		// sdl
 			size = 8;
 			off = -7;
+			info.lrType = LOADSTORE_LEFT;
+			break;
 		case 0x1E:		// lq
 		case 0x1F:		// sq
 			size = 16;
diff --git a/pcsx2/DebugTools/MIPSAnalyst.h b/pcsx2/DebugTools/MIPSAnalyst.h
index 5176872e57..65fab05509 100644
--- a/pcsx2/DebugTools/MIPSAnalyst.h
+++ b/pcsx2/DebugTools/MIPSAnalyst.h
@@ -41,6 +41,8 @@ namespace MIPSAnalyst
 
 	void ScanForFunctions(u32 startAddr, u32 endAddr, bool insertSymbols);
 
+	enum LoadStoreLRType { LOADSTORE_NORMAL, LOADSTORE_LEFT, LOADSTORE_RIGHT };
+
 	typedef struct {
 		DebugInterface* cpu;
 		u32 opcodeAddress;
@@ -61,6 +63,7 @@ namespace MIPSAnalyst
 
 		// data access
 		bool isDataAccess;
+		LoadStoreLRType lrType;
 		int dataSize;
 		u32 dataAddress;
 
diff --git a/pcsx2/gui/Debugger/CtrlDisassemblyView.cpp b/pcsx2/gui/Debugger/CtrlDisassemblyView.cpp
index d722e5b0c0..ec67f64f7f 100644
--- a/pcsx2/gui/Debugger/CtrlDisassemblyView.cpp
+++ b/pcsx2/gui/Debugger/CtrlDisassemblyView.cpp
@@ -847,6 +847,9 @@ void CtrlDisassemblyView::updateStatusBarText()
 			if (!cpu->isValidAddress(line.info.dataAddress))
 			{
 				sprintf(text,"Invalid address %08X",line.info.dataAddress);
+			} else if (line.info.lrType == MIPSAnalyst::LOADSTORE_NORMAL && line.info.dataAddress % line.info.dataSize)
+			{
+				sprintf(text,"Unaligned address %08X",line.info.dataAddress);
 			} else {
 				switch (line.info.dataSize)
 				{
@@ -858,7 +861,16 @@ void CtrlDisassemblyView::updateStatusBarText()
 					break;
 				case 4:
 					{
-						u32 data = cpu->read32(line.info.dataAddress);
+						u32 data;
+						if (line.info.lrType != MIPSAnalyst::LOADSTORE_NORMAL)
+						{
+							u32 address = line.info.dataAddress;
+							data = cpu->read32(address & ~3) >> (address & 3) * 8;
+							data |= cpu->read32((address + 3) & ~3) << (4 - (address & 3)) * 8;
+						} else {
+							data = cpu->read32(line.info.dataAddress);
+						}
+
 						const std::string addressSymbol = symbolMap.GetLabelString(data);
 						if (!addressSymbol.empty())
 						{
@@ -870,7 +882,16 @@ void CtrlDisassemblyView::updateStatusBarText()
 					}
 				case 8:
 					{
-						u64 data = cpu->read64(line.info.dataAddress);
+						u64 data;
+						if (line.info.lrType != MIPSAnalyst::LOADSTORE_NORMAL)
+						{
+							u32 address = line.info.dataAddress;
+							data = cpu->read64(address & ~7) >> (address & 7) * 8;
+							data |= cpu->read64((address + 7) & ~7) << (8 - (address & 7)) * 8;
+						} else {
+							data = cpu->read64(line.info.dataAddress);
+						}
+
 						sprintf(text,"[%08X] = %016llX",line.info.dataAddress,data);
 						break;
 					}