diff --git a/pcsx2/VMManager.cpp b/pcsx2/VMManager.cpp
index 5968a2459a..806d14e9b6 100644
--- a/pcsx2/VMManager.cpp
+++ b/pcsx2/VMManager.cpp
@@ -2741,6 +2741,9 @@ void VMManager::EnforceAchievementsChallengeModeSettings()
 	EmuConfig.Speedhacks.EECycleRate =
 		std::max<decltype(EmuConfig.Speedhacks.EECycleRate)>(EmuConfig.Speedhacks.EECycleRate, 0);
 	EmuConfig.Speedhacks.EECycleSkip = 0;
+
+	// Async mix breaks games.
+	EmuConfig.SPU2.SynchMode = Pcsx2Config::SPU2Options::SynchronizationMode::TimeStretch;
 }
 
 void VMManager::LogUnsafeSettingsToConsole(const std::string& messages)