diff --git a/pcsx2/GS/Renderers/Vulkan/GSDeviceVK.cpp b/pcsx2/GS/Renderers/Vulkan/GSDeviceVK.cpp
index e92fd22291..99dac6c5bf 100644
--- a/pcsx2/GS/Renderers/Vulkan/GSDeviceVK.cpp
+++ b/pcsx2/GS/Renderers/Vulkan/GSDeviceVK.cpp
@@ -1521,6 +1521,14 @@ void GSDeviceVK::OMSetRenderTargets(GSTexture* rt, GSTexture* ds, const GSVector
 	{
 		if (vkRt)
 		{
+			// NVIDIA drivers appear to return random garbage when sampling the RT via a feedback loop, if the load op for
+			// the render pass is CLEAR. Using vkCmdClearAttachments() doesn't work, so we have to clear the image instead.
+			if (feedback_loop & FeedbackLoopFlag_ReadAndWriteRT && vkRt->GetState() == GSTexture::State::Cleared &&
+				g_vulkan_context->IsDeviceNVIDIA())
+			{
+				vkRt->CommitClear();
+			}
+
 			vkRt->TransitionToLayout((feedback_loop & FeedbackLoopFlag_ReadAndWriteRT) ?
 				GSTextureVK::Layout::FeedbackLoop :
 										 GSTextureVK::Layout::ColorAttachment);
diff --git a/pcsx2/GS/Renderers/Vulkan/VKContext.h b/pcsx2/GS/Renderers/Vulkan/VKContext.h
index 98738efbcd..9ec4c8dcf4 100644
--- a/pcsx2/GS/Renderers/Vulkan/VKContext.h
+++ b/pcsx2/GS/Renderers/Vulkan/VKContext.h
@@ -128,6 +128,9 @@ public:
 		return m_device_properties.limits.maxImageDimension2D;
 	}
 
+	/// Returns true if running on an NVIDIA GPU.
+	__fi bool IsDeviceNVIDIA() const { return (m_device_properties.vendorID == 0x10DE); }
+
 	// Creates a simple render pass.
 	__ri VkRenderPass GetRenderPass(VkFormat color_format, VkFormat depth_format,
 		VkAttachmentLoadOp color_load_op = VK_ATTACHMENT_LOAD_OP_LOAD,