diff --git a/CHANGES b/CHANGES
index 2f83f881e..b44292475 100644
--- a/CHANGES
+++ b/CHANGES
@@ -40,6 +40,7 @@ Misc:
  - GBA Video: Clean up unused timers
  - Qt: Manage window sizes slightly better
  - Qt: Remember scale option independent of core dimensions
+ - GB: Reset active region when reloading ROM
 
 0.5.0: (2016-09-19)
 Features:
diff --git a/src/gb/gb.c b/src/gb/gb.c
index 68fc4bcbc..72cb775ac 100644
--- a/src/gb/gb.c
+++ b/src/gb/gb.c
@@ -102,6 +102,11 @@ bool GBLoadROM(struct GB* gb, struct VFile* vf) {
 	gb->memory.romSize = gb->pristineRomSize;
 	gb->romCrc32 = doCrc32(gb->memory.rom, gb->memory.romSize);
 
+	if (gb->cpu) {
+		struct LR35902Core* cpu = gb->cpu;
+		cpu->memory.setActiveRegion(cpu, cpu->pc);
+	}
+
 	// TODO: error check
 	return true;
 }