diff --git a/CMakeLists.txt b/CMakeLists.txt
index ed522e70b..8ccebef30 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -257,15 +257,10 @@ if(WIN32)
 	endif()
 elseif(UNIX)
 	set(USE_PTHREADS ON)
-	add_definitions(-DUSE_PTHREADS)
 
 	if(CMAKE_SYSTEM_NAME STREQUAL "Linux")
 		add_definitions(-D_GNU_SOURCE)
 	endif()
-	if(NOT APPLE AND NOT HAIKU)
-		set(CMAKE_C_FLAGS "${CMAKE_C_FLAGS} -pthread")
-		set(CMAKE_CXX_FLAGS "${CMAKE_CXX_FLAGS} -pthread")
-	endif()
 
 	list(APPEND CORE_VFS_SRC ${CMAKE_CURRENT_SOURCE_DIR}/src/util/vfs/vfs-fd.c ${CMAKE_CURRENT_SOURCE_DIR}/src/util/vfs/vfs-dirent.c)
 	file(GLOB OS_SRC ${CMAKE_CURRENT_SOURCE_DIR}/src/platform/posix/*.c)
@@ -351,6 +346,7 @@ if(3DS OR WII)
 	add_definitions(-D_GNU_SOURCE)
 endif()
 
+include(CheckCCompilerFlag)
 include(CheckFunctionExists)
 include(CheckIncludeFiles)
 check_function_exists(strdup HAVE_STRDUP)
@@ -402,6 +398,27 @@ endif()
 check_function_exists(chmod HAVE_CHMOD)
 check_function_exists(umask HAVE_UMASK)
 
+if(USE_PTHREADS)
+	check_include_files("pthread.h" HAVE_PTHREAD_H)
+	if(HAVE_PTHREAD_H)
+		check_c_compiler_flag(-pthread HAVE_PTHREAD)
+		if(HAVE_PTHREAD AND NOT APPLE AND NOT HAIKU)
+			set(CMAKE_C_FLAGS "${CMAKE_C_FLAGS} -pthread")
+			set(CMAKE_CXX_FLAGS "${CMAKE_CXX_FLAGS} -pthread")
+		endif()
+
+		check_function_exists(pthread_create HAVE_PTHREAD_CREATE)
+		if(HAVE_PTHREAD_CREATE)
+			add_definitions(-DUSE_PTHREADS)
+
+			check_include_files("pthread_np.h" HAVE_PTHREAD_NP_H)
+
+			check_function_exists(pthread_setname_np HAVE_PTHREAD_SETNAME_NP)
+			check_function_exists(pthread_set_name_np HAVE_PTHREAD_SET_NAME_NP)
+		endif()
+	endif()
+endif()
+
 set(FUNCTION_DEFINES)
 
 if(HAVE_STRDUP)
@@ -443,6 +460,18 @@ if(HAVE_UMASK)
 	list(APPEND FUNCTION_DEFINES HAVE_UMASK)
 endif()
 
+if(HAVE_PTHREAD_NP_H)
+	list(APPEND FUNCTION_DEFINES HAVE_PTHREAD_NP_H)
+endif()
+
+if(HAVE_PTHREAD_SETNAME_NP)
+	list(APPEND FUNCTION_DEFINES HAVE_PTHREAD_SETNAME_NP)
+endif()
+
+if(HAVE_PTHREAD_SET_NAME_NP)
+	list(APPEND FUNCTION_DEFINES HAVE_PTHREAD_SET_NAME_NP)
+endif()
+
 # Feature dependencies
 set(FEATURE_DEFINES)
 set(FEATURE_FLAGS)
diff --git a/include/mgba-util/platform/posix/threading.h b/include/mgba-util/platform/posix/threading.h
index 468e1460c..38aac8f62 100644
--- a/include/mgba-util/platform/posix/threading.h
+++ b/include/mgba-util/platform/posix/threading.h
@@ -12,7 +12,7 @@ CXX_GUARD_START
 
 #include <pthread.h>
 #include <sys/time.h>
-#if defined(__FreeBSD__) || defined(__OpenBSD__)
+#ifdef HAVE_PTHREAD_NP_H
 #include <pthread_np.h>
 #elif defined(__HAIKU__)
 #include <OS.h>
@@ -85,20 +85,15 @@ static inline int ThreadJoin(Thread thread) {
 }
 
 static inline int ThreadSetName(const char* name) {
-#ifdef __APPLE__
-#if __ENVIRONMENT_MAC_OS_X_VERSION_MIN_REQUIRED__ >= 1060
+#if defined(__APPLE__) && defined(HAVE_PTHREAD_SETNAME_NP)
 	return pthread_setname_np(name);
-#else
-	UNUSED(name);
-	return 0;
-#endif
-#elif defined(__FreeBSD__) || defined(__OpenBSD__)
+#elif defined(HAVE_PTHREAD_SET_NAME_NP)
 	pthread_set_name_np(pthread_self(), name);
 	return 0;
 #elif defined(__HAIKU__)
 	rename_thread(find_thread(NULL), name);
 	return 0;
-#elif !defined(BUILD_PANDORA) // Pandora's glibc is too old
+#elif defined(HAVE_PTHREAD_SETNAME_NP)
 	return pthread_setname_np(pthread_self(), name);
 #else
 	UNUSED(name);