diff --git a/CHANGES b/CHANGES
index 08d9526ff..f3a8cc539 100644
--- a/CHANGES
+++ b/CHANGES
@@ -19,6 +19,7 @@ Other fixes:
  - Core: Fix inconsistencies with setting game-specific overrides (fixes mgba.io/i/2963)
  - Debugger: Fix writing to specific segment in command-line debugger
  - GB Serialize: Prevent loading invalid states where LY >= 144 in modes other than 1
+ - GBA Hardware: Fix loading states unconditionally overwriting GPIO memory
  - GBA: Fix getting game info for multiboot ROMs
  - Qt: Fix savestate preview sizes with different scales (fixes mgba.io/i/2560)
  - Qt: Fix potential crash when configuring shortcuts
diff --git a/include/mgba/gba/interface.h b/include/mgba/gba/interface.h
index cbbb4d23a..298292dd3 100644
--- a/include/mgba/gba/interface.h
+++ b/include/mgba/gba/interface.h
@@ -68,7 +68,9 @@ enum GBAHardwareDevice {
 	HW_TILT = 16,
 	HW_GB_PLAYER = 32,
 	HW_GB_PLAYER_DETECTION = 64,
-	HW_EREADER = 128
+	HW_EREADER = 128,
+
+	HW_GPIO = HW_RTC | HW_RUMBLE | HW_LIGHT_SENSOR | HW_GYRO | HW_TILT,
 };
 
 struct Configuration;
diff --git a/src/gba/cart/gpio.c b/src/gba/cart/gpio.c
index 0bffbc088..48cb8c340 100644
--- a/src/gba/cart/gpio.c
+++ b/src/gba/cart/gpio.c
@@ -502,7 +502,7 @@ void GBAHardwareDeserialize(struct GBACartridgeHardware* hw, const struct GBASer
 	LOAD_16(hw->direction, 0, &state->hw.pinDirection);
 	hw->devices = state->hw.devices;
 
-	if (hw->gpioBase) {
+	if ((hw->devices & HW_GPIO) && hw->gpioBase) {
 		if (hw->readWrite) {
 			STORE_16(hw->pinState, 0, hw->gpioBase);
 			STORE_16(hw->direction, 2, hw->gpioBase);