diff --git a/src/core/host_interface.cpp b/src/core/host_interface.cpp
index 35b90d2f6..356ba681e 100644
--- a/src/core/host_interface.cpp
+++ b/src/core/host_interface.cpp
@@ -199,53 +199,57 @@ void HostInterface::AddFormattedOSDMessage(float duration, const char* format, .
   AddOSDMessage(std::move(message), duration);
 }
 
-std::string HostInterface::GetBIOSDirectory() const
+std::string HostInterface::GetBIOSDirectory()
 {
+  std::string dir = GetStringSettingValue("BIOS", "SearchDirectory", "");
+  if (!dir.empty())
+    return dir;
+
   return GetUserDirectoryRelativePath("bios");
 }
 
 std::optional<std::vector<u8>> HostInterface::GetBIOSImage(ConsoleRegion region)
 {
-  const std::string* bios_path;
+  std::string bios_dir = GetBIOSDirectory();
+  std::string bios_name;
   switch (region)
   {
     case ConsoleRegion::NTSC_J:
-      bios_path = &g_settings.bios_path_ntsc_j;
+      bios_name = GetStringSettingValue("BIOS", "PathNTSCJ", "");
       break;
 
     case ConsoleRegion::PAL:
-      bios_path = &g_settings.bios_path_pal;
+      bios_name = GetStringSettingValue("BIOS", "PAL", "");
       break;
 
     case ConsoleRegion::NTSC_U:
     default:
-      bios_path = &g_settings.bios_path_ntsc_u;
+      bios_name = GetStringSettingValue("BIOS", "PathNTSCU", "");
       break;
   }
 
-  if (bios_path->empty())
+  if (bios_name.empty())
   {
     // auto-detect
-    return FindBIOSImageInDirectory(region, GetBIOSDirectory().c_str());
+    return FindBIOSImageInDirectory(region, bios_dir.c_str());
   }
 
   // try the configured path
   std::optional<BIOS::Image> image = BIOS::LoadImageFromFile(
-    StringUtil::StdStringFromFormat("%s" FS_OSPATH_SEPARATOR_STR "%s", GetBIOSDirectory().c_str(), bios_path->c_str())
-      .c_str());
+    StringUtil::StdStringFromFormat("%s" FS_OSPATH_SEPARATOR_STR "%s", bios_dir.c_str(), bios_name.c_str()).c_str());
   if (!image.has_value())
   {
     g_host_interface->ReportFormattedError(
       g_host_interface->TranslateString("HostInterface", "Failed to load configured BIOS file '%s'"),
-      bios_path->c_str());
+      bios_name.c_str());
     return std::nullopt;
   }
 
   BIOS::Hash found_hash = BIOS::GetHash(*image);
-  Log_DevPrintf("Hash for BIOS '%s': %s", bios_path->c_str(), found_hash.ToString().c_str());
+  Log_DevPrintf("Hash for BIOS '%s': %s", bios_name.c_str(), found_hash.ToString().c_str());
 
   if (!BIOS::IsValidHashForRegion(region, found_hash))
-    Log_WarningPrintf("Hash for BIOS '%s' does not match region. This may cause issues.", bios_path->c_str());
+    Log_WarningPrintf("Hash for BIOS '%s' does not match region. This may cause issues.", bios_name.c_str());
 
   return image;
 }
@@ -330,11 +334,6 @@ HostInterface::FindBIOSImagesInDirectory(const char* directory)
   return results;
 }
 
-std::vector<std::pair<std::string, const BIOS::ImageInfo*>> HostInterface::FindBIOSImagesInUserDirectory()
-{
-  return FindBIOSImagesInDirectory(GetUserDirectoryRelativePath("bios").c_str());
-}
-
 bool HostInterface::LoadState(const char* filename)
 {
   std::unique_ptr<ByteStream> stream = FileSystem::OpenFile(filename, BYTESTREAM_OPEN_READ | BYTESTREAM_OPEN_STREAMED);
@@ -464,6 +463,7 @@ void HostInterface::SetDefaultSettings(SettingsInterface& si)
   si.SetBoolValue("Audio", "Sync", true);
   si.SetBoolValue("Audio", "DumpOnBoot", false);
 
+  si.SetStringValue("BIOS", "SearchDirectory", "");
   si.SetStringValue("BIOS", "PathNTSCU", "");
   si.SetStringValue("BIOS", "PathNTSCJ", "");
   si.SetStringValue("BIOS", "PathPAL", "");
diff --git a/src/core/host_interface.h b/src/core/host_interface.h
index 72743b510..b1e7166fe 100644
--- a/src/core/host_interface.h
+++ b/src/core/host_interface.h
@@ -119,7 +119,7 @@ public:
   virtual std::string TranslateStdString(const char* context, const char* str) const;
 
   /// Returns the path to the directory to search for BIOS images.
-  virtual std::string GetBIOSDirectory() const;
+  virtual std::string GetBIOSDirectory();
 
   /// Loads the BIOS image for the specified region.
   std::optional<std::vector<u8>> GetBIOSImage(ConsoleRegion region);
@@ -130,7 +130,6 @@ public:
 
   /// Returns a list of filenames and descriptions for BIOS images in a directory.
   std::vector<std::pair<std::string, const BIOS::ImageInfo*>> FindBIOSImagesInDirectory(const char* directory);
-  std::vector<std::pair<std::string, const BIOS::ImageInfo*>> FindBIOSImagesInUserDirectory();
 
   virtual void OnRunningGameChanged();
   virtual void OnSystemPerformanceCountersUpdated();
diff --git a/src/core/settings.cpp b/src/core/settings.cpp
index 6622525c7..1db3c91e2 100644
--- a/src/core/settings.cpp
+++ b/src/core/settings.cpp
@@ -157,9 +157,6 @@ void Settings::Load(SettingsInterface& si)
   gpu_fifo_size = static_cast<u32>(si.GetIntValue("Hacks", "GPUFIFOSize", DEFAULT_GPU_FIFO_SIZE));
   gpu_max_run_ahead = si.GetIntValue("Hacks", "GPUMaxRunAhead", DEFAULT_GPU_MAX_RUN_AHEAD);
 
-  bios_path_ntsc_u = si.GetStringValue("BIOS", "PathNTSCU", "");
-  bios_path_ntsc_j = si.GetStringValue("BIOS", "PathNTSCJ", "");
-  bios_path_pal = si.GetStringValue("BIOS", "PathPAL", "");
   bios_patch_tty_enable = si.GetBoolValue("BIOS", "PatchTTYEnable", false);
   bios_patch_fast_boot = si.GetBoolValue("BIOS", "PatchFastBoot", false);
 
@@ -273,9 +270,6 @@ void Settings::Save(SettingsInterface& si) const
   si.SetIntValue("Hacks", "GPUFIFOSize", gpu_fifo_size);
   si.SetIntValue("Hacks", "GPUMaxRunAhead", gpu_max_run_ahead);
 
-  si.SetStringValue("BIOS", "PathNTSCJ", bios_path_ntsc_j.c_str());
-  si.SetStringValue("BIOS", "PathNTSCU", bios_path_ntsc_u.c_str());
-  si.SetStringValue("BIOS", "PathPAL", bios_path_pal.c_str());
   si.SetBoolValue("BIOS", "PatchTTYEnable", bios_patch_tty_enable);
   si.SetBoolValue("BIOS", "PatchFastBoot", bios_patch_fast_boot);
 
diff --git a/src/core/settings.h b/src/core/settings.h
index 199f677c6..ed2879bbe 100644
--- a/src/core/settings.h
+++ b/src/core/settings.h
@@ -147,9 +147,6 @@ struct Settings
 
   // TODO: Controllers, memory cards, etc.
 
-  std::string bios_path_ntsc_j;
-  std::string bios_path_ntsc_u;
-  std::string bios_path_pal;
   bool bios_patch_tty_enable = false;
   bool bios_patch_fast_boot = false;
 
diff --git a/src/duckstation-libretro/libretro_host_interface.cpp b/src/duckstation-libretro/libretro_host_interface.cpp
index 24b953722..fa4039d29 100644
--- a/src/duckstation-libretro/libretro_host_interface.cpp
+++ b/src/duckstation-libretro/libretro_host_interface.cpp
@@ -646,7 +646,7 @@ bool LibretroHostInterface::HasCoreVariablesChanged()
   return (g_retro_environment_callback(RETRO_ENVIRONMENT_GET_VARIABLE_UPDATE, &changed) && changed);
 }
 
-std::string LibretroHostInterface::GetBIOSDirectory() const
+std::string LibretroHostInterface::GetBIOSDirectory()
 {
   // Assume BIOS files are located in system directory.
   const char* system_directory = nullptr;
diff --git a/src/duckstation-libretro/libretro_host_interface.h b/src/duckstation-libretro/libretro_host_interface.h
index c0671c7a0..e4cb649c1 100644
--- a/src/duckstation-libretro/libretro_host_interface.h
+++ b/src/duckstation-libretro/libretro_host_interface.h
@@ -28,7 +28,7 @@ public:
   std::string GetGameMemoryCardPath(const char* game_code, u32 slot) const override;
   std::string GetShaderCacheBasePath() const override;
   std::string GetStringSettingValue(const char* section, const char* key, const char* default_value = "") override;
-  std::string GetBIOSDirectory() const override;
+  std::string GetBIOSDirectory() override;
 
   // Called by frontend
   void retro_get_system_av_info(struct retro_system_av_info* info);
diff --git a/src/duckstation-qt/biossettingswidget.cpp b/src/duckstation-qt/biossettingswidget.cpp
index 5da0d57f1..31c76032d 100644
--- a/src/duckstation-qt/biossettingswidget.cpp
+++ b/src/duckstation-qt/biossettingswidget.cpp
@@ -1,6 +1,7 @@
 #include "biossettingswidget.h"
 #include "core/bios.h"
 #include "qthostinterface.h"
+#include "qtutils.h"
 #include "settingsdialog.h"
 #include "settingwidgetbinder.h"
 #include <QtWidgets/QFileDialog>
@@ -9,6 +10,9 @@
 static void populateDropDownForRegion(ConsoleRegion region, QComboBox* cb,
                                       std::vector<std::pair<std::string, const BIOS::ImageInfo*>>& images)
 {
+  QSignalBlocker sb(cb);
+  cb->clear();
+
   cb->addItem(QIcon(QStringLiteral(":/icons/system-search.png")),
               QT_TRANSLATE_NOOP("BIOSSettingsWidget", "Auto-Detect"));
 
@@ -94,14 +98,7 @@ BIOSSettingsWidget::BIOSSettingsWidget(QtHostInterface* host_interface, QWidget*
                              tr("Patches the BIOS to skip the console's boot animation. Does not work with all games, "
                                 "but usually safe to enabled."));
 
-  auto images = m_host_interface->FindBIOSImagesInUserDirectory();
-  populateDropDownForRegion(ConsoleRegion::NTSC_J, m_ui.imageNTSCJ, images);
-  populateDropDownForRegion(ConsoleRegion::NTSC_U, m_ui.imageNTSCU, images);
-  populateDropDownForRegion(ConsoleRegion::PAL, m_ui.imagePAL, images);
-
-  setDropDownValue(m_ui.imageNTSCJ, m_host_interface->GetStringSettingValue("BIOS", "PathNTSCJ", ""));
-  setDropDownValue(m_ui.imageNTSCU, m_host_interface->GetStringSettingValue("BIOS", "PathNTSCU", ""));
-  setDropDownValue(m_ui.imagePAL, m_host_interface->GetStringSettingValue("BIOS", "PathPAL", ""));
+  refreshList();
 
   connect(m_ui.imageNTSCJ, QOverload<int>::of(&QComboBox::currentIndexChanged), [this](int index) {
     m_host_interface->SetStringSettingValue("BIOS", "PathNTSCJ",
@@ -118,6 +115,52 @@ BIOSSettingsWidget::BIOSSettingsWidget(QtHostInterface* host_interface, QWidget*
                                             m_ui.imagePAL->itemData(index).toString().toStdString().c_str());
     m_host_interface->applySettings();
   });
+
+  connect(m_ui.refresh, &QPushButton::clicked, this, &BIOSSettingsWidget::refreshList);
+
+  std::string current_search_directory = g_host_interface->GetBIOSDirectory();
+  m_ui.searchDirectory->setText(QString::fromStdString(current_search_directory));
+  connect(m_ui.searchDirectory, &QLineEdit::textChanged, [this](const QString& text) {
+    if (text.isEmpty())
+    {
+      m_host_interface->RemoveSettingValue("BIOS", "SearchDirectory");
+    }
+    else
+    {
+      m_host_interface->SetStringSettingValue("BIOS", "SearchDirectory", text.toStdString().c_str());
+    }
+    refreshList();
+  });
+  connect(m_ui.browseSearchDirectory, &QPushButton::clicked, this, &BIOSSettingsWidget::browseSearchDirectory);
+  connect(m_ui.openSearchDirectory, &QPushButton::clicked, this, &BIOSSettingsWidget::openSearchDirectory);
 }
 
 BIOSSettingsWidget::~BIOSSettingsWidget() = default;
+
+void BIOSSettingsWidget::refreshList()
+{
+  auto images = m_host_interface->FindBIOSImagesInDirectory(m_host_interface->GetBIOSDirectory().c_str());
+  populateDropDownForRegion(ConsoleRegion::NTSC_J, m_ui.imageNTSCJ, images);
+  populateDropDownForRegion(ConsoleRegion::NTSC_U, m_ui.imageNTSCU, images);
+  populateDropDownForRegion(ConsoleRegion::PAL, m_ui.imagePAL, images);
+
+  setDropDownValue(m_ui.imageNTSCJ, m_host_interface->GetStringSettingValue("BIOS", "PathNTSCJ", ""));
+  setDropDownValue(m_ui.imageNTSCU, m_host_interface->GetStringSettingValue("BIOS", "PathNTSCU", ""));
+  setDropDownValue(m_ui.imagePAL, m_host_interface->GetStringSettingValue("BIOS", "PathPAL", ""));
+}
+
+void BIOSSettingsWidget::browseSearchDirectory()
+{
+  QString directory = QFileDialog::getExistingDirectory(QtUtils::GetRootWidget(this), tr("Select Directory"),
+                                                        m_ui.searchDirectory->text());
+  if (directory.isEmpty())
+    return;
+
+  m_ui.searchDirectory->setText(directory);
+}
+
+void BIOSSettingsWidget::openSearchDirectory()
+{
+  QString dir = QString::fromStdString(m_host_interface->GetBIOSDirectory());
+  QtUtils::OpenURL(this, QUrl::fromLocalFile(dir));
+}
diff --git a/src/duckstation-qt/biossettingswidget.h b/src/duckstation-qt/biossettingswidget.h
index 7e324f40e..39f604e31 100644
--- a/src/duckstation-qt/biossettingswidget.h
+++ b/src/duckstation-qt/biossettingswidget.h
@@ -15,6 +15,11 @@ public:
   explicit BIOSSettingsWidget(QtHostInterface* host_interface, QWidget* parent, SettingsDialog* dialog);
   ~BIOSSettingsWidget();
 
+private Q_SLOTS:
+  void refreshList();
+  void browseSearchDirectory();
+  void openSearchDirectory();
+
 private:
   Ui::BIOSSettingsWidget m_ui;
 
diff --git a/src/duckstation-qt/biossettingswidget.ui b/src/duckstation-qt/biossettingswidget.ui
index e89b3298b..c728c0949 100644
--- a/src/duckstation-qt/biossettingswidget.ui
+++ b/src/duckstation-qt/biossettingswidget.ui
@@ -6,8 +6,8 @@
    <rect>
     <x>0</x>
     <y>0</y>
-    <width>472</width>
-    <height>259</height>
+    <width>529</width>
+    <height>330</height>
    </rect>
   </property>
   <property name="windowTitle">
@@ -32,13 +32,6 @@
       <string>BIOS Selection</string>
      </property>
      <layout class="QGridLayout" name="gridLayout">
-      <item row="0" column="0">
-       <widget class="QLabel" name="label">
-        <property name="text">
-         <string>NTSC-J (Japan):</string>
-        </property>
-       </widget>
-      </item>
       <item row="0" column="1">
        <widget class="QComboBox" name="imageNTSCJ">
         <property name="sizePolicy">
@@ -49,23 +42,6 @@
         </property>
        </widget>
       </item>
-      <item row="1" column="0">
-       <widget class="QLabel" name="label_2">
-        <property name="text">
-         <string>NTSC-U/C (US/Canada):</string>
-        </property>
-       </widget>
-      </item>
-      <item row="1" column="1">
-       <widget class="QComboBox" name="imageNTSCU">
-        <property name="sizePolicy">
-         <sizepolicy hsizetype="Expanding" vsizetype="Fixed">
-          <horstretch>0</horstretch>
-          <verstretch>0</verstretch>
-         </sizepolicy>
-        </property>
-       </widget>
-      </item>
       <item row="2" column="0">
        <widget class="QLabel" name="label_5">
         <property name="text">
@@ -73,6 +49,20 @@
         </property>
        </widget>
       </item>
+      <item row="0" column="0">
+       <widget class="QLabel" name="label">
+        <property name="text">
+         <string>NTSC-J (Japan):</string>
+        </property>
+       </widget>
+      </item>
+      <item row="1" column="0">
+       <widget class="QLabel" name="label_2">
+        <property name="text">
+         <string>NTSC-U/C (US/Canada):</string>
+        </property>
+       </widget>
+      </item>
       <item row="2" column="1">
        <widget class="QComboBox" name="imagePAL">
         <property name="sizePolicy">
@@ -83,6 +73,80 @@
         </property>
        </widget>
       </item>
+      <item row="1" column="1">
+       <widget class="QComboBox" name="imageNTSCU">
+        <property name="sizePolicy">
+         <sizepolicy hsizetype="Expanding" vsizetype="Fixed">
+          <horstretch>0</horstretch>
+          <verstretch>0</verstretch>
+         </sizepolicy>
+        </property>
+       </widget>
+      </item>
+      <item row="3" column="1">
+       <layout class="QHBoxLayout" name="horizontalLayout_2">
+        <item>
+         <spacer name="horizontalSpacer">
+          <property name="orientation">
+           <enum>Qt::Horizontal</enum>
+          </property>
+          <property name="sizeHint" stdset="0">
+           <size>
+            <width>40</width>
+            <height>20</height>
+           </size>
+          </property>
+         </spacer>
+        </item>
+        <item>
+         <widget class="QPushButton" name="openSearchDirectory">
+          <property name="text">
+           <string>Open in Explorer...</string>
+          </property>
+         </widget>
+        </item>
+        <item>
+         <widget class="QPushButton" name="refresh">
+          <property name="text">
+           <string>Refresh List</string>
+          </property>
+         </widget>
+        </item>
+       </layout>
+      </item>
+     </layout>
+    </widget>
+   </item>
+   <item>
+    <widget class="QGroupBox" name="groupBox_3">
+     <property name="title">
+      <string>BIOS Directory</string>
+     </property>
+     <layout class="QGridLayout" name="gridLayout_2">
+      <item row="0" column="0" colspan="2">
+       <widget class="QLabel" name="label_3">
+        <property name="text">
+         <string>DuckStation will search for BIOS images in this directory.</string>
+        </property>
+        <property name="wordWrap">
+         <bool>true</bool>
+        </property>
+       </widget>
+      </item>
+      <item row="1" column="0" colspan="2">
+       <layout class="QHBoxLayout" name="horizontalLayout">
+        <item>
+         <widget class="QLineEdit" name="searchDirectory"/>
+        </item>
+        <item>
+         <widget class="QPushButton" name="browseSearchDirectory">
+          <property name="text">
+           <string>Browse...</string>
+          </property>
+         </widget>
+        </item>
+       </layout>
+      </item>
      </layout>
     </widget>
    </item>