diff --git a/Source/Core/AudioCommon/XAudio2Stream.cpp b/Source/Core/AudioCommon/XAudio2Stream.cpp
index 12954fc5bf..69c503f310 100644
--- a/Source/Core/AudioCommon/XAudio2Stream.cpp
+++ b/Source/Core/AudioCommon/XAudio2Stream.cpp
@@ -25,8 +25,7 @@ private:
 
 public:
   StreamingVoiceContext(IXAudio2* pXAudio2, CMixer* pMixer, Common::Event& pSyncEvent);
-
-  ~StreamingVoiceContext();
+  virtual ~StreamingVoiceContext();
 
   void Stop();
   void Play();
diff --git a/Source/Core/AudioCommon/XAudio2_7Stream.cpp b/Source/Core/AudioCommon/XAudio2_7Stream.cpp
index 06fb645c95..1abf6d2096 100644
--- a/Source/Core/AudioCommon/XAudio2_7Stream.cpp
+++ b/Source/Core/AudioCommon/XAudio2_7Stream.cpp
@@ -25,8 +25,7 @@ private:
 
 public:
   StreamingVoiceContext2_7(IXAudio2* pXAudio2, CMixer* pMixer, Common::Event& pSyncEvent);
-
-  ~StreamingVoiceContext2_7();
+  virtual ~StreamingVoiceContext2_7();
 
   void Stop();
   void Play();
diff --git a/Source/Core/Common/Config/Section.h b/Source/Core/Common/Config/Section.h
index 8b36ce157e..0a4662d156 100644
--- a/Source/Core/Common/Config/Section.h
+++ b/Source/Core/Common/Config/Section.h
@@ -27,6 +27,7 @@ class Section
 
 public:
   Section(LayerType layer, System system, const std::string& name);
+  virtual ~Section() = default;
 
   virtual bool Exists(const std::string& key) const;
   bool Delete(const std::string& key);
diff --git a/Source/Core/Core/HW/MMIO.cpp b/Source/Core/Core/HW/MMIO.cpp
index 8ee341554d..a6dcdeebd6 100644
--- a/Source/Core/Core/HW/MMIO.cpp
+++ b/Source/Core/Core/HW/MMIO.cpp
@@ -20,14 +20,14 @@ template <typename T>
 class ReadHandlingMethod
 {
 public:
-  virtual ~ReadHandlingMethod() {}
+  virtual ~ReadHandlingMethod() = default;
   virtual void AcceptReadVisitor(ReadHandlingMethodVisitor<T>& v) const = 0;
 };
 template <typename T>
 class WriteHandlingMethod
 {
 public:
-  virtual ~WriteHandlingMethod() {}
+  virtual ~WriteHandlingMethod() = default;
   virtual void AcceptWriteVisitor(WriteHandlingMethodVisitor<T>& v) const = 0;
 };
 
@@ -39,7 +39,7 @@ class ConstantHandlingMethod : public ReadHandlingMethod<T>
 {
 public:
   explicit ConstantHandlingMethod(T value) : value_(value) {}
-  virtual ~ConstantHandlingMethod() {}
+  virtual ~ConstantHandlingMethod() = default;
   void AcceptReadVisitor(ReadHandlingMethodVisitor<T>& v) const override
   {
     v.VisitConstant(value_);
@@ -62,7 +62,7 @@ class NopHandlingMethod : public WriteHandlingMethod<T>
 {
 public:
   NopHandlingMethod() {}
-  virtual ~NopHandlingMethod() {}
+  virtual ~NopHandlingMethod() = default;
   void AcceptWriteVisitor(WriteHandlingMethodVisitor<T>& v) const override { v.VisitNop(); }
 };
 template <typename T>
@@ -79,7 +79,7 @@ class DirectHandlingMethod : public ReadHandlingMethod<T>, public WriteHandlingM
 {
 public:
   DirectHandlingMethod(T* addr, u32 mask) : addr_(addr), mask_(mask) {}
-  virtual ~DirectHandlingMethod() {}
+  virtual ~DirectHandlingMethod() = default;
   void AcceptReadVisitor(ReadHandlingMethodVisitor<T>& v) const override
   {
     v.VisitDirect(addr_, mask_);
@@ -132,7 +132,7 @@ public:
   {
   }
 
-  virtual ~ComplexHandlingMethod() {}
+  virtual ~ComplexHandlingMethod() = default;
   void AcceptReadVisitor(ReadHandlingMethodVisitor<T>& v) const override
   {
     v.VisitComplex(&read_lambda_);
@@ -304,6 +304,8 @@ void ReadHandler<T>::ResetMethod(ReadHandlingMethod<T>* method)
 
   struct FuncCreatorVisitor : public ReadHandlingMethodVisitor<T>
   {
+    virtual ~FuncCreatorVisitor() = default;
+
     std::function<T(u32)> ret;
 
     void VisitConstant(T value) override
@@ -356,6 +358,8 @@ void WriteHandler<T>::ResetMethod(WriteHandlingMethod<T>* method)
 
   struct FuncCreatorVisitor : public WriteHandlingMethodVisitor<T>
   {
+    virtual ~FuncCreatorVisitor() = default;
+
     std::function<void(u32, T)> ret;
 
     void VisitNop() override
diff --git a/Source/VSProps/Base.props b/Source/VSProps/Base.props
index 77732dc364..31336f3c07 100644
--- a/Source/VSProps/Base.props
+++ b/Source/VSProps/Base.props
@@ -117,6 +117,14 @@
                 Currently jits use some annoying code patterns which makes this common
       -->
       <DisableSpecificWarnings>4245;%(DisableSpecificWarnings)</DisableSpecificWarnings>
+      <!-- Enable some off-by-default warnings
+      4263  Non-virtual member function hides base class virtual function
+      4265  Class has virtual functions, but destructor is not virtual
+      4946  Reinterpret cast between related types
+      -->
+      <!-- Externals are currently not compatible with this. Can still uncomment locally.
+      <AdditionalOptions>/we4263 /we4265 /we4946 %(AdditionalOptions)</AdditionalOptions>
+      -->
     </ClCompile>
     <!--ClCompile Debug-->
     <ClCompile Condition="'$(Configuration)'=='Debug'">