diff --git a/Source/Core/Core/Analytics.cpp b/Source/Core/Core/Analytics.cpp
index b76f3b09f4..e6f9db25c2 100644
--- a/Source/Core/Core/Analytics.cpp
+++ b/Source/Core/Core/Analytics.cpp
@@ -131,9 +131,34 @@ void DolphinAnalytics::ReportGameStart()
   builder.AddData("type", "game-start");
   Send(builder);
 
+  // Reset per-game state.
+  m_reported_quirks.fill(false);
   InitializePerformanceSampling();
 }
 
+// Keep in sync with enum class GameQuirk definition.
+const char* GAME_QUIRKS_NAMES[] = {
+    "icache-matters",  // ICACHE_MATTERS
+};
+static_assert(sizeof(GAME_QUIRKS_NAMES) / sizeof(GAME_QUIRKS_NAMES[0]) ==
+                  static_cast<u32>(GameQuirk::COUNT),
+              "Game quirks names and enum definition are out of sync.");
+
+void DolphinAnalytics::ReportGameQuirk(GameQuirk quirk)
+{
+  u32 quirk_idx = static_cast<u32>(quirk);
+
+  // Only report once per run.
+  if (m_reported_quirks[quirk_idx])
+    return;
+  m_reported_quirks[quirk_idx] = true;
+
+  Common::AnalyticsReportBuilder builder(m_per_game_builder);
+  builder.AddData("type", "quirk");
+  builder.AddData("quirk", GAME_QUIRKS_NAMES[quirk_idx]);
+  Send(builder);
+}
+
 void DolphinAnalytics::ReportPerformanceInfo(PerformanceSample&& sample)
 {
   if (ShouldStartPerformanceSampling())
diff --git a/Source/Core/Core/Analytics.h b/Source/Core/Core/Analytics.h
index c0725efd51..0de0f839f8 100644
--- a/Source/Core/Core/Analytics.h
+++ b/Source/Core/Core/Analytics.h
@@ -4,6 +4,7 @@
 
 #pragma once
 
+#include <array>
 #include <memory>
 #include <mutex>
 #include <string>
@@ -18,6 +19,14 @@
 // Non generic part of the Dolphin Analytics framework. See Common/Analytics.h
 // for the main documentation.
 
+enum class GameQuirk
+{
+  // Sometimes code run from ICache is different from its mirror in RAM.
+  ICACHE_MATTERS = 0,
+
+  COUNT,
+};
+
 class DolphinAnalytics
 {
 public:
@@ -42,6 +51,10 @@ public:
   // per-game base data.
   void ReportGameStart();
 
+  // Generates a report for a special condition being hit by a game. This is automatically throttled
+  // to once per game run.
+  void ReportGameQuirk(GameQuirk quirk);
+
   struct PerformanceSample
   {
     double speed_ratio;  // See SystemTimers::GetEstimatedEmulationPerformance().
@@ -93,6 +106,9 @@ private:
   bool m_sampling_performance_info = false;  // Whether we are currently collecting samples.
   std::vector<PerformanceSample> m_performance_samples;
 
+  // What quirks have already been reported about the current game.
+  std::array<bool, static_cast<size_t>(GameQuirk::COUNT)> m_reported_quirks;
+
   // Builder that contains all non variable data that should be sent with all
   // reports.
   Common::AnalyticsReportBuilder m_base_builder;
diff --git a/Source/Core/Core/PowerPC/PPCCache.cpp b/Source/Core/Core/PowerPC/PPCCache.cpp
index 1b8e41b5b1..f3cdefb0c3 100644
--- a/Source/Core/Core/PowerPC/PPCCache.cpp
+++ b/Source/Core/Core/PowerPC/PPCCache.cpp
@@ -8,6 +8,7 @@
 
 #include "Common/ChunkFile.h"
 #include "Common/Swap.h"
+#include "Core/Analytics.h"
 #include "Core/HW/Memmap.h"
 #include "Core/PowerPC/JitInterface.h"
 #include "Core/PowerPC/PowerPC.h"
@@ -148,6 +149,13 @@ u32 InstructionCache::ReadInstruction(u32 addr)
   // update plru
   plru[set] = (plru[set] & ~s_plru_mask[t]) | s_plru_value[t];
   u32 res = Common::swap32(data[set][t][(addr >> 2) & 7]);
+  u32 inmem = Memory::Read_U32(addr);
+  if (res != inmem)
+  {
+    INFO_LOG(POWERPC, "ICache read at %08x returned stale data: CACHED: %08x vs. RAM: %08x", addr,
+             res, inmem);
+    DolphinAnalytics::Instance()->ReportGameQuirk(GameQuirk::ICACHE_MATTERS);
+  }
   return res;
 }