diff --git a/Source/Core/VideoBackends/D3D/D3DGfx.cpp b/Source/Core/VideoBackends/D3D/D3DGfx.cpp
index a4d1f5b8b9..27b4f0a4a0 100644
--- a/Source/Core/VideoBackends/D3D/D3DGfx.cpp
+++ b/Source/Core/VideoBackends/D3D/D3DGfx.cpp
@@ -239,9 +239,10 @@ void Gfx::SetSamplerState(u32 index, const SamplerState& state)
   D3D::stateman->SetSampler(index, m_state_cache.Get(state));
 }
 
-void Gfx::SetComputeImageTexture(AbstractTexture* texture, bool read, bool write)
+void Gfx::SetComputeImageTexture(u32 index, AbstractTexture* texture, bool read, bool write)
 {
-  D3D::stateman->SetComputeUAV(texture ? static_cast<DXTexture*>(texture)->GetD3DUAV() : nullptr);
+  D3D::stateman->SetComputeUAV(index,
+                               texture ? static_cast<DXTexture*>(texture)->GetD3DUAV() : nullptr);
 }
 
 void Gfx::UnbindTexture(const AbstractTexture* texture)
diff --git a/Source/Core/VideoBackends/D3D/D3DGfx.h b/Source/Core/VideoBackends/D3D/D3DGfx.h
index e23867e73b..07c47e93af 100644
--- a/Source/Core/VideoBackends/D3D/D3DGfx.h
+++ b/Source/Core/VideoBackends/D3D/D3DGfx.h
@@ -52,7 +52,7 @@ public:
   void SetScissorRect(const MathUtil::Rectangle<int>& rc) override;
   void SetTexture(u32 index, const AbstractTexture* texture) override;
   void SetSamplerState(u32 index, const SamplerState& state) override;
-  void SetComputeImageTexture(AbstractTexture* texture, bool read, bool write) override;
+  void SetComputeImageTexture(u32 index, AbstractTexture* texture, bool read, bool write) override;
   void UnbindTexture(const AbstractTexture* texture) override;
   void SetViewport(float x, float y, float width, float height, float near_depth,
                    float far_depth) override;
diff --git a/Source/Core/VideoBackends/D3D/D3DState.cpp b/Source/Core/VideoBackends/D3D/D3DState.cpp
index 06f01792f5..0372252b9a 100644
--- a/Source/Core/VideoBackends/D3D/D3DState.cpp
+++ b/Source/Core/VideoBackends/D3D/D3DState.cpp
@@ -222,13 +222,14 @@ void StateManager::SetTextureByMask(u32 textureSlotMask, ID3D11ShaderResourceVie
   }
 }
 
-void StateManager::SetComputeUAV(ID3D11UnorderedAccessView* uav)
+void StateManager::SetComputeUAV(u32 index, ID3D11UnorderedAccessView* uav)
 {
-  if (m_compute_image == uav)
+  if (m_compute_images[index] == uav)
     return;
 
-  m_compute_image = uav;
-  D3D::context->CSSetUnorderedAccessViews(0, 1, &uav, nullptr);
+  m_compute_images[index] = uav;
+  D3D::context->CSSetUnorderedAccessViews(0, static_cast<u32>(m_compute_images.size()),
+                                          m_compute_images.data(), nullptr);
 }
 
 void StateManager::SetComputeShader(ID3D11ComputeShader* shader)
diff --git a/Source/Core/VideoBackends/D3D/D3DState.h b/Source/Core/VideoBackends/D3D/D3DState.h
index eba58c2431..0893220e71 100644
--- a/Source/Core/VideoBackends/D3D/D3DState.h
+++ b/Source/Core/VideoBackends/D3D/D3DState.h
@@ -218,7 +218,7 @@ public:
 
   // Binds constant buffers/textures/samplers to the compute shader stage.
   // We don't track these explicitly because it's not often-used.
-  void SetComputeUAV(ID3D11UnorderedAccessView* uav);
+  void SetComputeUAV(u32 index, ID3D11UnorderedAccessView* uav);
   void SetComputeShader(ID3D11ComputeShader* shader);
   void SyncComputeBindings();
 
@@ -277,9 +277,11 @@ private:
 
   // Compute resources are synced with the graphics resources when we need them.
   ID3D11Buffer* m_compute_constants = nullptr;
-  std::array<ID3D11ShaderResourceView*, 8> m_compute_textures{};
-  std::array<ID3D11SamplerState*, 8> m_compute_samplers{};
-  ID3D11UnorderedAccessView* m_compute_image = nullptr;
+  std::array<ID3D11ShaderResourceView*, VideoCommon::MAX_COMPUTE_SHADER_SAMPLERS>
+      m_compute_textures{};
+  std::array<ID3D11SamplerState*, VideoCommon::MAX_COMPUTE_SHADER_SAMPLERS> m_compute_samplers{};
+  std::array<ID3D11UnorderedAccessView*, VideoCommon::MAX_COMPUTE_SHADER_SAMPLERS>
+      m_compute_images{};
   ID3D11ComputeShader* m_compute_shader = nullptr;
 };
 
diff --git a/Source/Core/VideoBackends/D3D12/D3D12Gfx.cpp b/Source/Core/VideoBackends/D3D12/D3D12Gfx.cpp
index 3f8e6ae4f3..3f6035feda 100644
--- a/Source/Core/VideoBackends/D3D12/D3D12Gfx.cpp
+++ b/Source/Core/VideoBackends/D3D12/D3D12Gfx.cpp
@@ -263,7 +263,7 @@ void Gfx::SetSamplerState(u32 index, const SamplerState& state)
   m_dirty_bits |= DirtyState_Samplers;
 }
 
-void Gfx::SetComputeImageTexture(AbstractTexture* texture, bool read, bool write)
+void Gfx::SetComputeImageTexture(u32 index, AbstractTexture* texture, bool read, bool write)
 {
   const DXTexture* dxtex = static_cast<const DXTexture*>(texture);
   if (m_state.compute_image_texture == dxtex)
diff --git a/Source/Core/VideoBackends/D3D12/D3D12Gfx.h b/Source/Core/VideoBackends/D3D12/D3D12Gfx.h
index 77ce4da899..b3426cb95e 100644
--- a/Source/Core/VideoBackends/D3D12/D3D12Gfx.h
+++ b/Source/Core/VideoBackends/D3D12/D3D12Gfx.h
@@ -60,7 +60,7 @@ public:
   void SetScissorRect(const MathUtil::Rectangle<int>& rc) override;
   void SetTexture(u32 index, const AbstractTexture* texture) override;
   void SetSamplerState(u32 index, const SamplerState& state) override;
-  void SetComputeImageTexture(AbstractTexture* texture, bool read, bool write) override;
+  void SetComputeImageTexture(u32 index, AbstractTexture* texture, bool read, bool write) override;
   void UnbindTexture(const AbstractTexture* texture) override;
   void SetViewport(float x, float y, float width, float height, float near_depth,
                    float far_depth) override;
diff --git a/Source/Core/VideoBackends/Metal/MTLGfx.h b/Source/Core/VideoBackends/Metal/MTLGfx.h
index c1a698711a..e92ae285e6 100644
--- a/Source/Core/VideoBackends/Metal/MTLGfx.h
+++ b/Source/Core/VideoBackends/Metal/MTLGfx.h
@@ -59,7 +59,7 @@ public:
   void SetScissorRect(const MathUtil::Rectangle<int>& rc) override;
   void SetTexture(u32 index, const AbstractTexture* texture) override;
   void SetSamplerState(u32 index, const SamplerState& state) override;
-  void SetComputeImageTexture(AbstractTexture* texture, bool read, bool write) override;
+  void SetComputeImageTexture(u32 index, AbstractTexture* texture, bool read, bool write) override;
   void UnbindTexture(const AbstractTexture* texture) override;
   void SetViewport(float x, float y, float width, float height, float near_depth,
                    float far_depth) override;
diff --git a/Source/Core/VideoBackends/Metal/MTLGfx.mm b/Source/Core/VideoBackends/Metal/MTLGfx.mm
index 1137c45e5f..f37dce39c7 100644
--- a/Source/Core/VideoBackends/Metal/MTLGfx.mm
+++ b/Source/Core/VideoBackends/Metal/MTLGfx.mm
@@ -386,7 +386,7 @@ void Metal::Gfx::SetSamplerState(u32 index, const SamplerState& state)
   g_state_tracker->SetSampler(index, state);
 }
 
-void Metal::Gfx::SetComputeImageTexture(AbstractTexture* texture, bool read, bool write)
+void Metal::Gfx::SetComputeImageTexture(u32, AbstractTexture* texture, bool read, bool write)
 {
   g_state_tracker->SetComputeTexture(static_cast<const Texture*>(texture));
 }
diff --git a/Source/Core/VideoBackends/OGL/OGLGfx.cpp b/Source/Core/VideoBackends/OGL/OGLGfx.cpp
index e545ed7f4b..fb773a6a2d 100644
--- a/Source/Core/VideoBackends/OGL/OGLGfx.cpp
+++ b/Source/Core/VideoBackends/OGL/OGLGfx.cpp
@@ -22,6 +22,7 @@
 #include "VideoCommon/Present.h"
 #include "VideoCommon/VideoConfig.h"
 
+#include <algorithm>
 #include <string_view>
 
 namespace OGL
@@ -303,8 +304,11 @@ void OGLGfx::DispatchComputeShader(const AbstractShader* shader, u32 groupsize_x
     static_cast<const OGLPipeline*>(m_current_pipeline)->GetProgram()->shader.Bind();
 
   // Barrier to texture can be used for reads.
-  if (m_bound_image_texture)
+  if (std::any_of(m_bound_image_textures.begin(), m_bound_image_textures.end(),
+                  [](auto image) { return image != nullptr; }))
+  {
     glMemoryBarrier(GL_TEXTURE_UPDATE_BARRIER_BIT);
+  }
 }
 
 void OGLGfx::SelectLeftBuffer()
@@ -652,23 +656,23 @@ void OGLGfx::SetSamplerState(u32 index, const SamplerState& state)
   g_sampler_cache->SetSamplerState(index, state);
 }
 
-void OGLGfx::SetComputeImageTexture(AbstractTexture* texture, bool read, bool write)
+void OGLGfx::SetComputeImageTexture(u32 index, AbstractTexture* texture, bool read, bool write)
 {
-  if (m_bound_image_texture == texture)
+  if (m_bound_image_textures[index] == texture)
     return;
 
   if (texture)
   {
     const GLenum access = read ? (write ? GL_READ_WRITE : GL_READ_ONLY) : GL_WRITE_ONLY;
-    glBindImageTexture(0, static_cast<OGLTexture*>(texture)->GetGLTextureId(), 0, GL_TRUE, 0,
+    glBindImageTexture(index, static_cast<OGLTexture*>(texture)->GetGLTextureId(), 0, GL_TRUE, 0,
                        access, static_cast<OGLTexture*>(texture)->GetGLFormatForImageTexture());
   }
   else
   {
-    glBindImageTexture(0, 0, 0, GL_FALSE, 0, GL_READ_ONLY, GL_RGBA8);
+    glBindImageTexture(index, 0, 0, GL_FALSE, 0, GL_READ_ONLY, GL_RGBA8);
   }
 
-  m_bound_image_texture = texture;
+  m_bound_image_textures[index] = texture;
 }
 
 void OGLGfx::UnbindTexture(const AbstractTexture* texture)
@@ -683,10 +687,13 @@ void OGLGfx::UnbindTexture(const AbstractTexture* texture)
     m_bound_textures[i] = nullptr;
   }
 
-  if (m_bound_image_texture == texture)
+  for (size_t i = 0; i < m_bound_image_textures.size(); i++)
   {
-    glBindImageTexture(0, 0, 0, GL_FALSE, 0, GL_READ_ONLY, GL_RGBA8);
-    m_bound_image_texture = nullptr;
+    if (m_bound_image_textures[i] != texture)
+      continue;
+
+    glBindImageTexture(static_cast<GLuint>(i), 0, 0, GL_FALSE, 0, GL_READ_ONLY, GL_RGBA8);
+    m_bound_image_textures[i] = nullptr;
   }
 }
 
diff --git a/Source/Core/VideoBackends/OGL/OGLGfx.h b/Source/Core/VideoBackends/OGL/OGLGfx.h
index 8d552a661b..1f392c7296 100644
--- a/Source/Core/VideoBackends/OGL/OGLGfx.h
+++ b/Source/Core/VideoBackends/OGL/OGLGfx.h
@@ -49,7 +49,7 @@ public:
   void SetScissorRect(const MathUtil::Rectangle<int>& rc) override;
   void SetTexture(u32 index, const AbstractTexture* texture) override;
   void SetSamplerState(u32 index, const SamplerState& state) override;
-  void SetComputeImageTexture(AbstractTexture* texture, bool read, bool write) override;
+  void SetComputeImageTexture(u32 index, AbstractTexture* texture, bool read, bool write) override;
   void UnbindTexture(const AbstractTexture* texture) override;
   void SetViewport(float x, float y, float width, float height, float near_depth,
                    float far_depth) override;
@@ -103,6 +103,8 @@ private:
   std::unique_ptr<GLContext> m_main_gl_context;
   std::unique_ptr<OGLFramebuffer> m_system_framebuffer;
   std::array<const OGLTexture*, VideoCommon::MAX_PIXEL_SHADER_SAMPLERS> m_bound_textures{};
+  std::array<const AbstractTexture*, VideoCommon::MAX_COMPUTE_SHADER_SAMPLERS>
+      m_bound_image_textures{};
   AbstractTexture* m_bound_image_texture = nullptr;
   RasterizationState m_current_rasterization_state;
   DepthState m_current_depth_state;
diff --git a/Source/Core/VideoBackends/Vulkan/CommandBufferManager.cpp b/Source/Core/VideoBackends/Vulkan/CommandBufferManager.cpp
index be02034f67..3aa05dbaf0 100644
--- a/Source/Core/VideoBackends/Vulkan/CommandBufferManager.cpp
+++ b/Source/Core/VideoBackends/Vulkan/CommandBufferManager.cpp
@@ -157,8 +157,9 @@ VkDescriptorPool CommandBufferManager::CreateDescriptorPool(u32 max_descriptor_s
   const std::array<VkDescriptorPoolSize, 5> pool_sizes{{
       {VK_DESCRIPTOR_TYPE_UNIFORM_BUFFER_DYNAMIC, max_descriptor_sets * 3},
       {VK_DESCRIPTOR_TYPE_COMBINED_IMAGE_SAMPLER,
-       max_descriptor_sets * (VideoCommon::MAX_PIXEL_SHADER_SAMPLERS + NUM_COMPUTE_SHADER_SAMPLERS +
-                              NUM_UTILITY_PIXEL_SAMPLERS)},
+       max_descriptor_sets *
+           (VideoCommon::MAX_PIXEL_SHADER_SAMPLERS + VideoCommon::MAX_COMPUTE_SHADER_SAMPLERS +
+            NUM_UTILITY_PIXEL_SAMPLERS)},
       {VK_DESCRIPTOR_TYPE_STORAGE_BUFFER, max_descriptor_sets * 2},
       {VK_DESCRIPTOR_TYPE_UNIFORM_TEXEL_BUFFER, max_descriptor_sets * 3},
       {VK_DESCRIPTOR_TYPE_STORAGE_IMAGE, max_descriptor_sets * 1},
diff --git a/Source/Core/VideoBackends/Vulkan/Constants.h b/Source/Core/VideoBackends/Vulkan/Constants.h
index 255cfe4929..2bdceefe3b 100644
--- a/Source/Core/VideoBackends/Vulkan/Constants.h
+++ b/Source/Core/VideoBackends/Vulkan/Constants.h
@@ -49,9 +49,9 @@ enum DESCRIPTOR_SET_LAYOUT
 //       - 1 texel buffer (accessible from PS) [set=1, binding=8]
 //   - Compute
 //       - 1 uniform buffer [set=0, binding=0]
-//       - 2 combined image samplers [set=0, binding=1-2]
-//       - 2 texel buffers [set=0, binding=3-4]
-//       - 1 storage image [set=0, binding=5]
+//       - 8 combined image samplers [set=0, binding=1-8]
+//       - 2 texel buffers [set=0, binding=9-10]
+//       - 8 storage image [set=0, binding=11-18]
 //
 // All four pipeline layout share the first two descriptor sets (uniform buffers, PS samplers).
 // The third descriptor set (see bind points above) is used for storage or texel buffers.
@@ -78,7 +78,6 @@ enum UNIFORM_BUFFER_DESCRIPTOR_SET_BINDING
 constexpr u32 MAX_VERTEX_ATTRIBUTES = 16;
 
 // Number of pixel shader texture slots
-constexpr u32 NUM_COMPUTE_SHADER_SAMPLERS = 2;
 constexpr u32 NUM_UTILITY_PIXEL_SAMPLERS = 8;
 
 // Number of texel buffer binding points.
diff --git a/Source/Core/VideoBackends/Vulkan/ObjectCache.cpp b/Source/Core/VideoBackends/Vulkan/ObjectCache.cpp
index 6b8f66ae80..d899191614 100644
--- a/Source/Core/VideoBackends/Vulkan/ObjectCache.cpp
+++ b/Source/Core/VideoBackends/Vulkan/ObjectCache.cpp
@@ -148,13 +148,26 @@ bool ObjectCache::CreateDescriptorSetLayouts()
       {8, VK_DESCRIPTOR_TYPE_UNIFORM_TEXEL_BUFFER, 1, VK_SHADER_STAGE_FRAGMENT_BIT},
   }};
 
-  static const std::array<VkDescriptorSetLayoutBinding, 6> compute_set_bindings{{
+  static const std::array<VkDescriptorSetLayoutBinding, 19> compute_set_bindings{{
       {0, VK_DESCRIPTOR_TYPE_UNIFORM_BUFFER_DYNAMIC, 1, VK_SHADER_STAGE_COMPUTE_BIT},
       {1, VK_DESCRIPTOR_TYPE_COMBINED_IMAGE_SAMPLER, 1, VK_SHADER_STAGE_COMPUTE_BIT},
       {2, VK_DESCRIPTOR_TYPE_COMBINED_IMAGE_SAMPLER, 1, VK_SHADER_STAGE_COMPUTE_BIT},
-      {3, VK_DESCRIPTOR_TYPE_UNIFORM_TEXEL_BUFFER, 1, VK_SHADER_STAGE_COMPUTE_BIT},
-      {4, VK_DESCRIPTOR_TYPE_UNIFORM_TEXEL_BUFFER, 1, VK_SHADER_STAGE_COMPUTE_BIT},
-      {5, VK_DESCRIPTOR_TYPE_STORAGE_IMAGE, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {3, VK_DESCRIPTOR_TYPE_COMBINED_IMAGE_SAMPLER, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {4, VK_DESCRIPTOR_TYPE_COMBINED_IMAGE_SAMPLER, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {5, VK_DESCRIPTOR_TYPE_COMBINED_IMAGE_SAMPLER, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {6, VK_DESCRIPTOR_TYPE_COMBINED_IMAGE_SAMPLER, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {7, VK_DESCRIPTOR_TYPE_COMBINED_IMAGE_SAMPLER, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {8, VK_DESCRIPTOR_TYPE_COMBINED_IMAGE_SAMPLER, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {9, VK_DESCRIPTOR_TYPE_UNIFORM_TEXEL_BUFFER, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {10, VK_DESCRIPTOR_TYPE_UNIFORM_TEXEL_BUFFER, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {11, VK_DESCRIPTOR_TYPE_STORAGE_IMAGE, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {12, VK_DESCRIPTOR_TYPE_STORAGE_IMAGE, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {13, VK_DESCRIPTOR_TYPE_STORAGE_IMAGE, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {14, VK_DESCRIPTOR_TYPE_STORAGE_IMAGE, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {15, VK_DESCRIPTOR_TYPE_STORAGE_IMAGE, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {16, VK_DESCRIPTOR_TYPE_STORAGE_IMAGE, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {17, VK_DESCRIPTOR_TYPE_STORAGE_IMAGE, 1, VK_SHADER_STAGE_COMPUTE_BIT},
+      {18, VK_DESCRIPTOR_TYPE_STORAGE_IMAGE, 1, VK_SHADER_STAGE_COMPUTE_BIT},
   }};
 
   std::array<VkDescriptorSetLayoutBinding, 3> ubo_bindings = standard_ubo_bindings;
diff --git a/Source/Core/VideoBackends/Vulkan/ShaderCompiler.cpp b/Source/Core/VideoBackends/Vulkan/ShaderCompiler.cpp
index 3555a6c9b7..ab9b015cec 100644
--- a/Source/Core/VideoBackends/Vulkan/ShaderCompiler.cpp
+++ b/Source/Core/VideoBackends/Vulkan/ShaderCompiler.cpp
@@ -58,8 +58,8 @@ static const char COMPUTE_SHADER_HEADER[] = R"(
   // All resources are packed into one descriptor set for compute.
   #define UBO_BINDING(packing, x) layout(packing, set = 0, binding = (x - 1))
   #define SAMPLER_BINDING(x) layout(set = 0, binding = (1 + x))
-  #define TEXEL_BUFFER_BINDING(x) layout(set = 0, binding = (3 + x))
-  #define IMAGE_BINDING(format, x) layout(format, set = 0, binding = (5 + x))
+  #define TEXEL_BUFFER_BINDING(x) layout(set = 0, binding = (9 + x))
+  #define IMAGE_BINDING(format, x) layout(format, set = 0, binding = (11 + x))
 
   // hlsl to glsl function translation
   #define API_VULKAN 1
diff --git a/Source/Core/VideoBackends/Vulkan/StateTracker.cpp b/Source/Core/VideoBackends/Vulkan/StateTracker.cpp
index edf57ae3b1..d6e4e3c422 100644
--- a/Source/Core/VideoBackends/Vulkan/StateTracker.cpp
+++ b/Source/Core/VideoBackends/Vulkan/StateTracker.cpp
@@ -49,8 +49,10 @@ void StateTracker::DestroyInstance()
   // Clear everything out so this doesn't happen.
   for (auto& it : s_state_tracker->m_bindings.samplers)
     it.imageView = VK_NULL_HANDLE;
-  s_state_tracker->m_bindings.image_texture.imageView = VK_NULL_HANDLE;
+  for (auto& it : s_state_tracker->m_bindings.image_textures)
+    it.imageView = VK_NULL_HANDLE;
   s_state_tracker->m_dummy_texture.reset();
+  s_state_tracker->m_dummy_compute_texture.reset();
 
   s_state_tracker.reset();
 }
@@ -64,6 +66,14 @@ bool StateTracker::Initialize()
     return false;
   m_dummy_texture->TransitionToLayout(g_command_buffer_mgr->GetCurrentInitCommandBuffer(),
                                       VK_IMAGE_LAYOUT_SHADER_READ_ONLY_OPTIMAL);
+  // Create a dummy compute texture which can be used in place of a real binding
+  m_dummy_compute_texture = VKTexture::Create(
+      TextureConfig(1, 1, 1, 1, 1, AbstractTextureFormat::RGBA8, AbstractTextureFlag_ComputeImage),
+      "");
+  if (!m_dummy_compute_texture)
+    return false;
+  m_dummy_compute_texture->TransitionToLayout(g_command_buffer_mgr->GetCurrentInitCommandBuffer(),
+                                              VK_IMAGE_LAYOUT_GENERAL);
 
   // Initialize all samplers to point by default
   for (size_t i = 0; i < VideoCommon::MAX_PIXEL_SHADER_SAMPLERS; i++)
@@ -73,6 +83,13 @@ bool StateTracker::Initialize()
     m_bindings.samplers[i].sampler = g_object_cache->GetPointSampler();
   }
 
+  for (size_t i = 0; i < VideoCommon::MAX_COMPUTE_SHADER_SAMPLERS; i++)
+  {
+    m_bindings.image_textures[i].imageLayout = VK_IMAGE_LAYOUT_GENERAL;
+    m_bindings.image_textures[i].imageView = m_dummy_compute_texture->GetView();
+    m_bindings.image_textures[i].sampler = g_object_cache->GetPointSampler();
+  }
+
   // Default dirty flags include all descriptors
   InvalidateCachedState();
   return true;
@@ -217,13 +234,13 @@ void StateTracker::SetTexelBuffer(u32 index, VkBufferView view)
   m_dirty_flags |= DIRTY_FLAG_UTILITY_BINDINGS | DIRTY_FLAG_COMPUTE_BINDINGS;
 }
 
-void StateTracker::SetImageTexture(VkImageView view)
+void StateTracker::SetImageTexture(u32 index, VkImageView view)
 {
-  if (m_bindings.image_texture.imageView == view)
+  if (m_bindings.image_textures[index].imageView == view)
     return;
 
-  m_bindings.image_texture.imageView = view;
-  m_bindings.image_texture.imageLayout = VK_IMAGE_LAYOUT_GENERAL;
+  m_bindings.image_textures[index].imageView = view;
+  m_bindings.image_textures[index].imageLayout = VK_IMAGE_LAYOUT_GENERAL;
   m_dirty_flags |= DIRTY_FLAG_COMPUTE_BINDINGS;
 }
 
@@ -238,10 +255,13 @@ void StateTracker::UnbindTexture(VkImageView view)
     }
   }
 
-  if (m_bindings.image_texture.imageView == view)
+  for (VkDescriptorImageInfo& it : m_bindings.image_textures)
   {
-    m_bindings.image_texture.imageView = m_dummy_texture->GetView();
-    m_bindings.image_texture.imageLayout = VK_IMAGE_LAYOUT_SHADER_READ_ONLY_OPTIMAL;
+    if (it.imageView == view)
+    {
+      it.imageView = m_dummy_compute_texture->GetView();
+      it.imageLayout = VK_IMAGE_LAYOUT_SHADER_READ_ONLY_OPTIMAL;
+    }
   }
 }
 
@@ -667,7 +687,7 @@ void StateTracker::UpdateComputeDescriptorSet()
                    m_compute_descriptor_set,
                    1,
                    0,
-                   NUM_COMPUTE_SHADER_SAMPLERS,
+                   VideoCommon::MAX_COMPUTE_SHADER_SAMPLERS,
                    VK_DESCRIPTOR_TYPE_COMBINED_IMAGE_SAMPLER,
                    m_bindings.samplers.data(),
                    nullptr,
@@ -675,7 +695,7 @@ void StateTracker::UpdateComputeDescriptorSet()
     dswrites[2] = {VK_STRUCTURE_TYPE_WRITE_DESCRIPTOR_SET,
                    nullptr,
                    m_compute_descriptor_set,
-                   3,
+                   1 + VideoCommon::MAX_COMPUTE_SHADER_SAMPLERS,
                    0,
                    NUM_COMPUTE_TEXEL_BUFFERS,
                    VK_DESCRIPTOR_TYPE_UNIFORM_TEXEL_BUFFER,
@@ -685,11 +705,11 @@ void StateTracker::UpdateComputeDescriptorSet()
     dswrites[3] = {VK_STRUCTURE_TYPE_WRITE_DESCRIPTOR_SET,
                    nullptr,
                    m_compute_descriptor_set,
-                   5,
+                   1 + VideoCommon::MAX_COMPUTE_SHADER_SAMPLERS + NUM_COMPUTE_TEXEL_BUFFERS,
                    0,
-                   1,
+                   VideoCommon::MAX_COMPUTE_SHADER_SAMPLERS,
                    VK_DESCRIPTOR_TYPE_STORAGE_IMAGE,
-                   &m_bindings.image_texture,
+                   m_bindings.image_textures.data(),
                    nullptr,
                    nullptr};
 
diff --git a/Source/Core/VideoBackends/Vulkan/StateTracker.h b/Source/Core/VideoBackends/Vulkan/StateTracker.h
index 1113cfc994..8de5fd54cc 100644
--- a/Source/Core/VideoBackends/Vulkan/StateTracker.h
+++ b/Source/Core/VideoBackends/Vulkan/StateTracker.h
@@ -43,7 +43,7 @@ public:
   void SetSampler(u32 index, VkSampler sampler);
   void SetSSBO(VkBuffer buffer, VkDeviceSize offset, VkDeviceSize range);
   void SetTexelBuffer(u32 index, VkBufferView view);
-  void SetImageTexture(VkImageView view);
+  void SetImageTexture(u32 index, VkImageView view);
 
   void UnbindTexture(VkImageView view);
 
@@ -146,7 +146,7 @@ private:
     std::array<VkBufferView, NUM_COMPUTE_TEXEL_BUFFERS> texel_buffers;
     VkDescriptorBufferInfo ssbo;
     VkDescriptorBufferInfo gx_uber_vertex_ssbo;
-    VkDescriptorImageInfo image_texture;
+    std::array<VkDescriptorImageInfo, VideoCommon::MAX_COMPUTE_SHADER_SAMPLERS> image_textures;
   } m_bindings = {};
   std::array<VkDescriptorSet, NUM_GX_DESCRIPTOR_SETS> m_gx_descriptor_sets = {};
   std::array<VkDescriptorSet, NUM_UTILITY_DESCRIPTOR_SETS> m_utility_descriptor_sets = {};
@@ -158,6 +158,7 @@ private:
 
   // uniform buffers
   std::unique_ptr<VKTexture> m_dummy_texture;
+  std::unique_ptr<VKTexture> m_dummy_compute_texture;
 
   VKFramebuffer* m_framebuffer = nullptr;
   VkRenderPass m_current_render_pass = VK_NULL_HANDLE;
diff --git a/Source/Core/VideoBackends/Vulkan/VKGfx.cpp b/Source/Core/VideoBackends/Vulkan/VKGfx.cpp
index e514979c65..fdfeb5713b 100644
--- a/Source/Core/VideoBackends/Vulkan/VKGfx.cpp
+++ b/Source/Core/VideoBackends/Vulkan/VKGfx.cpp
@@ -512,13 +512,13 @@ void VKGfx::SetSamplerState(u32 index, const SamplerState& state)
   m_sampler_states[index] = state;
 }
 
-void VKGfx::SetComputeImageTexture(AbstractTexture* texture, bool read, bool write)
+void VKGfx::SetComputeImageTexture(u32 index, AbstractTexture* texture, bool read, bool write)
 {
   VKTexture* vk_texture = static_cast<VKTexture*>(texture);
   if (vk_texture)
   {
     StateTracker::GetInstance()->EndRenderPass();
-    StateTracker::GetInstance()->SetImageTexture(vk_texture->GetView());
+    StateTracker::GetInstance()->SetImageTexture(index, vk_texture->GetView());
     vk_texture->TransitionToLayout(g_command_buffer_mgr->GetCurrentCommandBuffer(),
                                    read ? (write ? VKTexture::ComputeImageLayout::ReadWrite :
                                                    VKTexture::ComputeImageLayout::ReadOnly) :
@@ -526,7 +526,7 @@ void VKGfx::SetComputeImageTexture(AbstractTexture* texture, bool read, bool wri
   }
   else
   {
-    StateTracker::GetInstance()->SetImageTexture(VK_NULL_HANDLE);
+    StateTracker::GetInstance()->SetImageTexture(index, VK_NULL_HANDLE);
   }
 }
 
diff --git a/Source/Core/VideoBackends/Vulkan/VKGfx.h b/Source/Core/VideoBackends/Vulkan/VKGfx.h
index c6d6201714..539b427a9d 100644
--- a/Source/Core/VideoBackends/Vulkan/VKGfx.h
+++ b/Source/Core/VideoBackends/Vulkan/VKGfx.h
@@ -66,7 +66,7 @@ public:
   void SetScissorRect(const MathUtil::Rectangle<int>& rc) override;
   void SetTexture(u32 index, const AbstractTexture* texture) override;
   void SetSamplerState(u32 index, const SamplerState& state) override;
-  void SetComputeImageTexture(AbstractTexture* texture, bool read, bool write) override;
+  void SetComputeImageTexture(u32 index, AbstractTexture* texture, bool read, bool write) override;
   void UnbindTexture(const AbstractTexture* texture) override;
   void SetViewport(float x, float y, float width, float height, float near_depth,
                    float far_depth) override;
diff --git a/Source/Core/VideoCommon/AbstractGfx.h b/Source/Core/VideoCommon/AbstractGfx.h
index 952369e11e..5d2679f68f 100644
--- a/Source/Core/VideoCommon/AbstractGfx.h
+++ b/Source/Core/VideoCommon/AbstractGfx.h
@@ -61,7 +61,7 @@ public:
   virtual void SetScissorRect(const MathUtil::Rectangle<int>& rc) {}
   virtual void SetTexture(u32 index, const AbstractTexture* texture) {}
   virtual void SetSamplerState(u32 index, const SamplerState& state) {}
-  virtual void SetComputeImageTexture(AbstractTexture* texture, bool read, bool write) {}
+  virtual void SetComputeImageTexture(u32 index, AbstractTexture* texture, bool read, bool write) {}
   virtual void UnbindTexture(const AbstractTexture* texture) {}
   virtual void SetViewport(float x, float y, float width, float height, float near_depth,
                            float far_depth)
diff --git a/Source/Core/VideoCommon/Constants.h b/Source/Core/VideoCommon/Constants.h
index 8da73e8054..bd939b1f3c 100644
--- a/Source/Core/VideoCommon/Constants.h
+++ b/Source/Core/VideoCommon/Constants.h
@@ -8,4 +8,5 @@
 namespace VideoCommon
 {
 constexpr u32 MAX_PIXEL_SHADER_SAMPLERS = 8;
-}
+constexpr u32 MAX_COMPUTE_SHADER_SAMPLERS = 8;
+}  // namespace VideoCommon
diff --git a/Source/Core/VideoCommon/TextureCacheBase.cpp b/Source/Core/VideoCommon/TextureCacheBase.cpp
index c26cbb5f4c..6198eea0ff 100644
--- a/Source/Core/VideoCommon/TextureCacheBase.cpp
+++ b/Source/Core/VideoCommon/TextureCacheBase.cpp
@@ -3009,7 +3009,7 @@ bool TextureCacheBase::DecodeTextureOnGPU(RcTcacheEntry& entry, u32 dst_level, c
                 aligned_height, src_offset, row_stride / bytes_per_buffer_elem,
                 palette_offset};
   g_vertex_manager->UploadUtilityUniforms(&uniforms, sizeof(uniforms));
-  g_gfx->SetComputeImageTexture(m_decoding_texture.get(), false, true);
+  g_gfx->SetComputeImageTexture(0, m_decoding_texture.get(), false, true);
 
   auto dispatch_groups =
       TextureConversionShaderTiled::GetDispatchCount(info, aligned_width, aligned_height);