diff --git a/Source/Core/Core/CoreTiming.cpp b/Source/Core/Core/CoreTiming.cpp
index d9872dcc3b..041c3b150e 100644
--- a/Source/Core/Core/CoreTiming.cpp
+++ b/Source/Core/Core/CoreTiming.cpp
@@ -224,8 +224,7 @@ u64 GetIdleTicks()
 // schedule things to be executed on the main thread.
 void ScheduleEvent_Threadsafe(int cyclesIntoFuture, int event_type, u64 userdata)
 {
-	// TODO: Fix UI thread safety problems, and enable this assertion
-	// _assert_msg_(POWERPC, !Core::IsCPUThread(), "ScheduleEvent_Threadsafe from wrong thread");
+	_assert_msg_(POWERPC, !Core::IsCPUThread(), "ScheduleEvent_Threadsafe from wrong thread");
 	std::lock_guard<std::mutex> lk(tsWriteLock);
 	Event ne;
 	ne.time = globalTimer + cyclesIntoFuture;
@@ -287,8 +286,8 @@ static void AddEventToQueue(Event* ne)
 // than Advance
 void ScheduleEvent(int cyclesIntoFuture, int event_type, u64 userdata)
 {
-	// TODO: Fix UI thread safety problems, and enable this assertion
-	//_assert_msg_(POWERPC, Core::IsCPUThread(), "ScheduleEvent from wrong thread");
+	_assert_msg_(POWERPC, Core::IsCPUThread() || Core::GetState() == Core::CORE_PAUSE,
+				 "ScheduleEvent from wrong thread");
 	Event *ne = GetNewEvent();
 	ne->userdata = userdata;
 	ne->type = event_type;
diff --git a/Source/Core/DolphinWX/FrameTools.cpp b/Source/Core/DolphinWX/FrameTools.cpp
index de41814259..4edb08980f 100644
--- a/Source/Core/DolphinWX/FrameTools.cpp
+++ b/Source/Core/DolphinWX/FrameTools.cpp
@@ -1584,17 +1584,21 @@ void CFrame::ConnectWiimote(int wm_idx, bool connect)
 {
 	if (Core::IsRunning() && SConfig::GetInstance().m_LocalCoreStartupParameter.bWii)
 	{
+		bool was_unpaused = Core::PauseAndLock(true);
 		GetUsbPointer()->AccessWiiMote(wm_idx | 0x100)->Activate(connect);
 		wxString msg(wxString::Format(_("Wiimote %i %s"), wm_idx + 1,
 					connect ? _("Connected") : _("Disconnected")));
 		Core::DisplayMessage(WxStrToStr(msg), 3000);
 		Host_UpdateMainFrame();
+		Core::PauseAndLock(false, was_unpaused);
 	}
 }
 
 void CFrame::OnConnectWiimote(wxCommandEvent& event)
 {
+	bool was_unpaused = Core::PauseAndLock(true);
 	ConnectWiimote(event.GetId() - IDM_CONNECT_WIIMOTE1, !GetUsbPointer()->AccessWiiMote((event.GetId() - IDM_CONNECT_WIIMOTE1) | 0x100)->IsConnected());
+	Core::PauseAndLock(false, was_unpaused);
 }
 
 // Toggle fullscreen. In Windows the fullscreen mode is accomplished by expanding the m_Panel to cover
@@ -1792,6 +1796,7 @@ void CFrame::UpdateGUI()
 	GetMenuBar()->FindItem(IDM_CONNECT_BALANCEBOARD)->Enable(RunningWii);
 	if (RunningWii)
 	{
+		bool was_unpaused = Core::PauseAndLock(true);
 		GetMenuBar()->FindItem(IDM_CONNECT_WIIMOTE1)->Check(GetUsbPointer()->
 				AccessWiiMote(0x0100)->IsConnected());
 		GetMenuBar()->FindItem(IDM_CONNECT_WIIMOTE2)->Check(GetUsbPointer()->
@@ -1802,6 +1807,7 @@ void CFrame::UpdateGUI()
 				AccessWiiMote(0x0103)->IsConnected());
 		GetMenuBar()->FindItem(IDM_CONNECT_BALANCEBOARD)->Check(GetUsbPointer()->
 				AccessWiiMote(0x0104)->IsConnected());
+		Core::PauseAndLock(false, was_unpaused);
 	}
 
 	if (m_ToolBar)