diff --git a/Source/Core/VideoCommon/DriverDetails.cpp b/Source/Core/VideoCommon/DriverDetails.cpp
index 1626e24d18..301c73d89f 100644
--- a/Source/Core/VideoCommon/DriverDetails.cpp
+++ b/Source/Core/VideoCommon/DriverDetails.cpp
@@ -108,7 +108,8 @@ static BugInfo m_known_bugs[] = {
      -1.0, true},
     {API_VULKAN, OS_ALL, VENDOR_IMGTEC, DRIVER_IMGTEC, Family::UNKNOWN,
      BUG_BROKEN_CLEAR_LOADOP_RENDERPASS, -1.0, -1.0, true},
-};
+    {API_VULKAN, OS_ALL, VENDOR_QUALCOMM, DRIVER_QUALCOMM, Family::UNKNOWN, BUG_BROKEN_D32F_CLEAR,
+     -1.0, -1.0, true}};
 
 static std::map<Bug, BugInfo> m_bugs;
 
diff --git a/Source/Core/VideoCommon/DriverDetails.h b/Source/Core/VideoCommon/DriverDetails.h
index 65b6c89fcb..9ace5f83b4 100644
--- a/Source/Core/VideoCommon/DriverDetails.h
+++ b/Source/Core/VideoCommon/DriverDetails.h
@@ -269,6 +269,13 @@ enum Bug
   // Started Version: 1.7
   // Ended Version: 1.10
   BUG_BROKEN_CLEAR_LOADOP_RENDERPASS,
+
+  // BUG: 32-bit depth clears are broken in the Adreno Vulkan driver, and have no effect.
+  // To work around this, we use a D24_S8 buffer instead, which results in a loss of accuracy.
+  // We still resolve this to a R32F texture, as there is no 24-bit format.
+  // Started version: -1
+  // Ended version: -1
+  BUG_BROKEN_D32F_CLEAR,
 };
 
 // Initializes our internal vendor, device family, and driver version
diff --git a/Source/Core/VideoCommon/FramebufferManagerBase.cpp b/Source/Core/VideoCommon/FramebufferManagerBase.cpp
index d33f72b2d8..530aac7584 100644
--- a/Source/Core/VideoCommon/FramebufferManagerBase.cpp
+++ b/Source/Core/VideoCommon/FramebufferManagerBase.cpp
@@ -7,6 +7,7 @@
 #include <memory>
 
 #include "VideoCommon/AbstractTexture.h"
+#include "VideoCommon/DriverDetails.h"
 #include "VideoCommon/RenderBase.h"
 
 std::unique_ptr<FramebufferManagerBase> g_framebuffer_manager;
@@ -17,5 +18,11 @@ FramebufferManagerBase::~FramebufferManagerBase() = default;
 
 AbstractTextureFormat FramebufferManagerBase::GetEFBDepthFormat()
 {
-  return AbstractTextureFormat::D32F;
+  // 32-bit depth clears are broken in the Adreno Vulkan driver, and have no effect.
+  // To work around this, we use a D24_S8 buffer instead, which results in a loss of accuracy.
+  // We still resolve this to a R32F texture, as there is no 24-bit format.
+  if (DriverDetails::HasBug(DriverDetails::BUG_BROKEN_D32F_CLEAR))
+    return AbstractTextureFormat::D24_S8;
+  else
+    return AbstractTextureFormat::D32F;
 }