diff --git a/Source/Core/VideoBackends/Vulkan/CommandBufferManager.cpp b/Source/Core/VideoBackends/Vulkan/CommandBufferManager.cpp
index 22f97b8888..59382166a9 100644
--- a/Source/Core/VideoBackends/Vulkan/CommandBufferManager.cpp
+++ b/Source/Core/VideoBackends/Vulkan/CommandBufferManager.cpp
@@ -371,13 +371,16 @@ void CommandBufferManager::SubmitCommandBuffer(u32 command_buffer_index,
                                      &present_image_index,
                                      nullptr};
 
-    res = vkQueuePresentKHR(g_vulkan_context->GetPresentQueue(), &present_info);
-    if (res != VK_SUCCESS)
+    m_last_present_result = vkQueuePresentKHR(g_vulkan_context->GetPresentQueue(), &present_info);
+    if (m_last_present_result != VK_SUCCESS)
     {
       // VK_ERROR_OUT_OF_DATE_KHR is not fatal, just means we need to recreate our swap chain.
-      if (res != VK_ERROR_OUT_OF_DATE_KHR && res != VK_SUBOPTIMAL_KHR)
-        LOG_VULKAN_ERROR(res, "vkQueuePresentKHR failed: ");
-      m_present_failed_flag.Set();
+      if (m_last_present_result != VK_ERROR_OUT_OF_DATE_KHR && res != VK_SUBOPTIMAL_KHR &&
+          m_last_present_result != VK_ERROR_FULL_SCREEN_EXCLUSIVE_MODE_LOST_EXT)
+      {
+        LOG_VULKAN_ERROR(m_last_present_result, "vkQueuePresentKHR failed: ");
+      }
+      m_last_present_failed.Set();
     }
   }
 
diff --git a/Source/Core/VideoBackends/Vulkan/CommandBufferManager.h b/Source/Core/VideoBackends/Vulkan/CommandBufferManager.h
index 350a576c04..da93553d70 100644
--- a/Source/Core/VideoBackends/Vulkan/CommandBufferManager.h
+++ b/Source/Core/VideoBackends/Vulkan/CommandBufferManager.h
@@ -79,7 +79,8 @@ public:
                            uint32_t present_image_index = 0xFFFFFFFF);
 
   // Was the last present submitted to the queue a failure? If so, we must recreate our swapchain.
-  bool CheckLastPresentFail() { return m_present_failed_flag.TestAndClear(); }
+  bool CheckLastPresentFail() { return m_last_present_failed.TestAndClear(); }
+  VkResult GetLastPresentResult() const { return m_last_present_result; }
 
   // Schedule a vulkan resource for destruction later on. This will occur when the command buffer
   // is next re-used, and the GPU has finished working with the specified resource.
@@ -136,7 +137,8 @@ private:
   VkSemaphore m_present_semaphore = VK_NULL_HANDLE;
   std::deque<PendingCommandBufferSubmit> m_pending_submits;
   std::mutex m_pending_submit_lock;
-  Common::Flag m_present_failed_flag;
+  Common::Flag m_last_present_failed;
+  VkResult m_last_present_result = VK_SUCCESS;
   bool m_use_threaded_submission = false;
 };
 
diff --git a/Source/Core/VideoBackends/Vulkan/Renderer.cpp b/Source/Core/VideoBackends/Vulkan/Renderer.cpp
index 648b019971..0628a5482b 100644
--- a/Source/Core/VideoBackends/Vulkan/Renderer.cpp
+++ b/Source/Core/VideoBackends/Vulkan/Renderer.cpp
@@ -280,13 +280,39 @@ void Renderer::BindBackbuffer(const ClearColor& clear_color)
   CheckForSurfaceChange();
   CheckForSurfaceResize();
 
-  VkResult res = g_command_buffer_mgr->CheckLastPresentFail() ? VK_ERROR_OUT_OF_DATE_KHR :
-                                                                m_swap_chain->AcquireNextImage();
-  if (res == VK_SUBOPTIMAL_KHR || res == VK_ERROR_OUT_OF_DATE_KHR)
+  // Check for exclusive fullscreen request.
+  if (m_swap_chain->GetCurrentFullscreenState() != m_swap_chain->GetNextFullscreenState() &&
+      !m_swap_chain->SetFullscreenState(m_swap_chain->GetNextFullscreenState()))
+  {
+    // if it fails, don't keep trying
+    m_swap_chain->SetNextFullscreenState(m_swap_chain->GetCurrentFullscreenState());
+  }
+
+  VkResult res = g_command_buffer_mgr->CheckLastPresentFail() ?
+                     g_command_buffer_mgr->GetLastPresentResult() :
+                     m_swap_chain->AcquireNextImage();
+  if (res != VK_SUCCESS)
   {
     // Execute cmdbuffer before resizing, as the last frame could still be presenting.
     ExecuteCommandBuffer(false, true);
-    m_swap_chain->ResizeSwapChain();
+
+    // Was this a lost exclusive fullscreen?
+    if (res == VK_ERROR_FULL_SCREEN_EXCLUSIVE_MODE_LOST_EXT)
+    {
+      // The present keeps returning exclusive mode lost unless we re-create the swap chain.
+      INFO_LOG(VIDEO, "Lost exclusive fullscreen.");
+      m_swap_chain->RecreateSwapChain();
+    }
+    else if (res == VK_SUBOPTIMAL_KHR || res == VK_ERROR_OUT_OF_DATE_KHR)
+    {
+      m_swap_chain->ResizeSwapChain();
+    }
+    else
+    {
+      ERROR_LOG(VIDEO, "Unknown present error 0x%08X, please report.", res);
+      m_swap_chain->RecreateSwapChain();
+    }
+
     res = m_swap_chain->AcquireNextImage();
   }
   if (res != VK_SUCCESS)
@@ -323,6 +349,19 @@ void Renderer::PresentBackbuffer()
   StateTracker::GetInstance()->InvalidateCachedState();
 }
 
+void Renderer::SetFullscreen(bool enable_fullscreen)
+{
+  if (!m_swap_chain->IsFullscreenSupported())
+    return;
+
+  m_swap_chain->SetNextFullscreenState(enable_fullscreen);
+}
+
+bool Renderer::IsFullscreen() const
+{
+  return m_swap_chain && m_swap_chain->GetCurrentFullscreenState();
+}
+
 void Renderer::ExecuteCommandBuffer(bool submit_off_thread, bool wait_for_completion)
 {
   StateTracker::GetInstance()->EndRenderPass();
diff --git a/Source/Core/VideoBackends/Vulkan/Renderer.h b/Source/Core/VideoBackends/Vulkan/Renderer.h
index 245ad777ec..43ed3bd45b 100644
--- a/Source/Core/VideoBackends/Vulkan/Renderer.h
+++ b/Source/Core/VideoBackends/Vulkan/Renderer.h
@@ -83,6 +83,8 @@ public:
                              u32 groups_z) override;
   void BindBackbuffer(const ClearColor& clear_color = {}) override;
   void PresentBackbuffer() override;
+  void SetFullscreen(bool enable_fullscreen) override;
+  bool IsFullscreen() const override;
 
   // Completes the current render pass, executes the command buffer, and restores state ready for
   // next render. Use when you want to kick the current buffer to make room for new data.
diff --git a/Source/Core/VideoBackends/Vulkan/SwapChain.cpp b/Source/Core/VideoBackends/Vulkan/SwapChain.cpp
index ef9b6f7265..66f20e5a6e 100644
--- a/Source/Core/VideoBackends/Vulkan/SwapChain.cpp
+++ b/Source/Core/VideoBackends/Vulkan/SwapChain.cpp
@@ -25,7 +25,8 @@
 namespace Vulkan
 {
 SwapChain::SwapChain(const WindowSystemInfo& wsi, VkSurfaceKHR surface, bool vsync)
-    : m_wsi(wsi), m_surface(surface), m_vsync_enabled(vsync)
+    : m_wsi(wsi), m_surface(surface), m_vsync_enabled(vsync),
+      m_fullscreen_supported(g_vulkan_context->SupportsExclusiveFullscreen(wsi, surface))
 {
 }
 
@@ -290,6 +291,7 @@ bool SwapChain::CreateSwapChain()
 
   // Store the old/current swap chain when recreating for resize
   VkSwapchainKHR old_swap_chain = m_swap_chain;
+  m_swap_chain = VK_NULL_HANDLE;
 
   // Now we can actually create the swap chain
   VkSwapchainCreateInfoKHR swap_chain_info = {VK_STRUCTURE_TYPE_SWAPCHAIN_CREATE_INFO_KHR,
@@ -322,8 +324,36 @@ bool SwapChain::CreateSwapChain()
     swap_chain_info.pQueueFamilyIndices = indices.data();
   }
 
-  res =
-      vkCreateSwapchainKHR(g_vulkan_context->GetDevice(), &swap_chain_info, nullptr, &m_swap_chain);
+#ifdef SUPPORTS_VULKAN_EXCLUSIVE_FULLSCREEN
+  if (m_fullscreen_supported)
+  {
+    VkSurfaceFullScreenExclusiveInfoEXT fullscreen_support = {};
+    swap_chain_info.pNext = &fullscreen_support;
+    fullscreen_support.sType = VK_STRUCTURE_TYPE_SURFACE_FULL_SCREEN_EXCLUSIVE_INFO_EXT;
+    fullscreen_support.fullScreenExclusive = VK_FULL_SCREEN_EXCLUSIVE_APPLICATION_CONTROLLED_EXT;
+
+    auto platform_info = g_vulkan_context->GetPlatformExclusiveFullscreenInfo(m_wsi);
+    fullscreen_support.pNext = &platform_info;
+
+    res = vkCreateSwapchainKHR(g_vulkan_context->GetDevice(), &swap_chain_info, nullptr,
+                               &m_swap_chain);
+    if (res != VK_SUCCESS)
+    {
+      // Try without exclusive fullscreen.
+      WARN_LOG(VIDEO, "Failed to create exclusive fullscreen swapchain, trying without.");
+      swap_chain_info.pNext = nullptr;
+      g_Config.backend_info.bSupportsExclusiveFullscreen = false;
+      g_ActiveConfig.backend_info.bSupportsExclusiveFullscreen = false;
+      m_fullscreen_supported = false;
+    }
+  }
+#endif
+
+  if (m_swap_chain == VK_NULL_HANDLE)
+  {
+    res = vkCreateSwapchainKHR(g_vulkan_context->GetDevice(), &swap_chain_info, nullptr,
+                               &m_swap_chain);
+  }
   if (res != VK_SUCCESS)
   {
     LOG_VULKAN_ERROR(res, "vkCreateSwapchainKHR failed: ");
@@ -414,6 +444,10 @@ void SwapChain::DestroySwapChain()
   if (m_swap_chain == VK_NULL_HANDLE)
     return;
 
+  // Release exclusive fullscreen before destroying.
+  if (m_current_fullscreen_state)
+    SetFullscreenState(false);
+
   vkDestroySwapchainKHR(g_vulkan_context->GetDevice(), m_swap_chain, nullptr);
   m_swap_chain = VK_NULL_HANDLE;
 }
@@ -464,6 +498,39 @@ bool SwapChain::SetVSync(bool enabled)
   return RecreateSwapChain();
 }
 
+bool SwapChain::SetFullscreenState(bool state)
+{
+#ifdef SUPPORTS_VULKAN_EXCLUSIVE_FULLSCREEN
+  if (m_current_fullscreen_state == state)
+    return true;
+
+  if (state)
+  {
+    VkResult res = vkAcquireFullScreenExclusiveModeEXT(g_vulkan_context->GetDevice(), m_swap_chain);
+    if (res != VK_SUCCESS)
+    {
+      LOG_VULKAN_ERROR(res, "vkAcquireFullScreenExclusiveModeEXT failed:");
+      return false;
+    }
+
+    INFO_LOG(VIDEO, "Exclusive fullscreen acquired.");
+  }
+  else
+  {
+    VkResult res = vkReleaseFullScreenExclusiveModeEXT(g_vulkan_context->GetDevice(), m_swap_chain);
+    if (res != VK_SUCCESS)
+      LOG_VULKAN_ERROR(res, "vkReleaseFullScreenExclusiveModeEXT failed:");
+
+    INFO_LOG(VIDEO, "Exclusive fullscreen released.");
+  }
+
+  m_current_fullscreen_state = state;
+  return true;
+#else
+  return false;
+#endif
+}
+
 bool SwapChain::RecreateSurface(void* native_handle)
 {
   // Destroy the old swap chain, images, and surface.
@@ -493,6 +560,13 @@ bool SwapChain::RecreateSurface(void* native_handle)
     return false;
   }
 
+  // Update exclusive fullscreen support (unlikely to change).
+  m_fullscreen_supported = g_vulkan_context->SupportsExclusiveFullscreen(m_wsi, m_surface);
+  g_Config.backend_info.bSupportsExclusiveFullscreen = m_fullscreen_supported;
+  g_ActiveConfig.backend_info.bSupportsExclusiveFullscreen = m_fullscreen_supported;
+  m_current_fullscreen_state = false;
+  m_next_fullscreen_state = false;
+
   // Finally re-create the swap chain
   if (!CreateSwapChain() || !SetupSwapChainImages())
     return false;
diff --git a/Source/Core/VideoBackends/Vulkan/SwapChain.h b/Source/Core/VideoBackends/Vulkan/SwapChain.h
index 4359f4663c..a6ee28d965 100644
--- a/Source/Core/VideoBackends/Vulkan/SwapChain.h
+++ b/Source/Core/VideoBackends/Vulkan/SwapChain.h
@@ -62,6 +62,17 @@ public:
   // Change vsync enabled state. This may fail as it causes a swapchain recreation.
   bool SetVSync(bool enabled);
 
+  // Is exclusive fullscreen supported?
+  bool IsFullscreenSupported() const { return m_fullscreen_supported; }
+
+  // Retrieves the "next" fullscreen state. Safe to call off-thread.
+  bool GetCurrentFullscreenState() const { return m_current_fullscreen_state; }
+  bool GetNextFullscreenState() const { return m_next_fullscreen_state; }
+  void SetNextFullscreenState(bool state) { m_next_fullscreen_state = state; }
+
+  // Updates the fullscreen state. Must call on-thread.
+  bool SetFullscreenState(bool state);
+
 private:
   bool SelectSurfaceFormat();
   bool SelectPresentMode();
@@ -86,7 +97,10 @@ private:
   VkSurfaceFormatKHR m_surface_format = {};
   VkPresentModeKHR m_present_mode = VK_PRESENT_MODE_RANGE_SIZE_KHR;
   AbstractTextureFormat m_texture_format = AbstractTextureFormat::Undefined;
-  bool m_vsync_enabled;
+  bool m_vsync_enabled = false;
+  bool m_fullscreen_supported = false;
+  bool m_current_fullscreen_state = false;
+  bool m_next_fullscreen_state = false;
 
   VkSwapchainKHR m_swap_chain = VK_NULL_HANDLE;
   std::vector<SwapChainImage> m_swap_chain_images;
diff --git a/Source/Core/VideoBackends/Vulkan/VulkanContext.cpp b/Source/Core/VideoBackends/Vulkan/VulkanContext.cpp
index 72eddd56c9..dc24839f88 100644
--- a/Source/Core/VideoBackends/Vulkan/VulkanContext.cpp
+++ b/Source/Core/VideoBackends/Vulkan/VulkanContext.cpp
@@ -88,7 +88,7 @@ bool VulkanContext::CheckValidationLayerAvailablility()
 VkInstance VulkanContext::CreateVulkanInstance(WindowSystemType wstype, bool enable_debug_report,
                                                bool enable_validation_layer)
 {
-  ExtensionList enabled_extensions;
+  std::vector<const char*> enabled_extensions;
   if (!SelectInstanceExtensions(&enabled_extensions, wstype, enable_debug_report))
     return VK_NULL_HANDLE;
 
@@ -143,8 +143,8 @@ VkInstance VulkanContext::CreateVulkanInstance(WindowSystemType wstype, bool ena
   return instance;
 }
 
-bool VulkanContext::SelectInstanceExtensions(ExtensionList* extension_list, WindowSystemType wstype,
-                                             bool enable_debug_report)
+bool VulkanContext::SelectInstanceExtensions(std::vector<const char*>* extension_list,
+                                             WindowSystemType wstype, bool enable_debug_report)
 {
   u32 extension_count = 0;
   VkResult res = vkEnumerateInstanceExtensionProperties(nullptr, &extension_count, nullptr);
@@ -168,7 +168,7 @@ bool VulkanContext::SelectInstanceExtensions(ExtensionList* extension_list, Wind
   for (const auto& extension_properties : available_extension_list)
     INFO_LOG(VIDEO, "Available extension: %s", extension_properties.extensionName);
 
-  auto SupportsExtension = [&](const char* name, bool required) {
+  auto AddExtension = [&](const char* name, bool required) {
     if (std::find_if(available_extension_list.begin(), available_extension_list.end(),
                      [&](const VkExtensionProperties& properties) {
                        return !strcmp(name, properties.extensionName);
@@ -186,45 +186,45 @@ bool VulkanContext::SelectInstanceExtensions(ExtensionList* extension_list, Wind
   };
 
   // Common extensions
-  if (wstype != WindowSystemType::Headless &&
-      !SupportsExtension(VK_KHR_SURFACE_EXTENSION_NAME, true))
+  if (wstype != WindowSystemType::Headless && !AddExtension(VK_KHR_SURFACE_EXTENSION_NAME, true))
   {
     return false;
   }
 
 #if defined(VK_USE_PLATFORM_WIN32_KHR)
   if (wstype == WindowSystemType::Windows &&
-      !SupportsExtension(VK_KHR_WIN32_SURFACE_EXTENSION_NAME, true))
+      !AddExtension(VK_KHR_WIN32_SURFACE_EXTENSION_NAME, true))
   {
     return false;
   }
 #endif
 #if defined(VK_USE_PLATFORM_XLIB_KHR)
-  if (wstype == WindowSystemType::X11 &&
-      !SupportsExtension(VK_KHR_XLIB_SURFACE_EXTENSION_NAME, true))
+  if (wstype == WindowSystemType::X11 && !AddExtension(VK_KHR_XLIB_SURFACE_EXTENSION_NAME, true))
   {
     return false;
   }
 #endif
 #if defined(VK_USE_PLATFORM_ANDROID_KHR)
   if (wstype == WindowSystemType::Android &&
-      !SupportsExtension(VK_KHR_ANDROID_SURFACE_EXTENSION_NAME, true))
+      !AddExtension(VK_KHR_ANDROID_SURFACE_EXTENSION_NAME, true))
   {
     return false;
   }
 #endif
 #if defined(VK_USE_PLATFORM_MACOS_MVK)
-  if (wstype == WindowSystemType::MacOS &&
-      !SupportsExtension(VK_MVK_MACOS_SURFACE_EXTENSION_NAME, true))
+  if (wstype == WindowSystemType::MacOS && !AddExtension(VK_MVK_MACOS_SURFACE_EXTENSION_NAME, true))
   {
     return false;
   }
 #endif
 
   // VK_EXT_debug_report
-  if (enable_debug_report && !SupportsExtension(VK_EXT_DEBUG_REPORT_EXTENSION_NAME, false))
+  if (enable_debug_report && !AddExtension(VK_EXT_DEBUG_REPORT_EXTENSION_NAME, false))
     WARN_LOG(VIDEO, "Vulkan: Debug report requested, but extension is not available.");
 
+  AddExtension(VK_KHR_GET_PHYSICAL_DEVICE_PROPERTIES_2_EXTENSION_NAME, false);
+  AddExtension(VK_KHR_GET_SURFACE_CAPABILITIES_2_EXTENSION_NAME, false);
+
   return true;
 }
 
@@ -254,26 +254,26 @@ VulkanContext::GPUList VulkanContext::EnumerateGPUs(VkInstance instance)
 void VulkanContext::PopulateBackendInfo(VideoConfig* config)
 {
   config->backend_info.api_type = APIType::Vulkan;
-  config->backend_info.bSupportsExclusiveFullscreen = false;  // Currently WSI does not allow this.
-  config->backend_info.bSupports3DVision = false;             // D3D-exclusive.
-  config->backend_info.bSupportsOversizedViewports = true;    // Assumed support.
-  config->backend_info.bSupportsEarlyZ = true;                // Assumed support.
-  config->backend_info.bSupportsPrimitiveRestart = true;      // Assumed support.
-  config->backend_info.bSupportsBindingLayout = false;        // Assumed support.
-  config->backend_info.bSupportsPaletteConversion = true;     // Assumed support.
-  config->backend_info.bSupportsClipControl = true;           // Assumed support.
-  config->backend_info.bSupportsMultithreading = true;        // Assumed support.
-  config->backend_info.bSupportsComputeShaders = true;        // Assumed support.
-  config->backend_info.bSupportsGPUTextureDecoding = true;    // Assumed support.
-  config->backend_info.bSupportsBitfield = true;              // Assumed support.
-  config->backend_info.bSupportsPartialDepthCopies = true;    // Assumed support.
-  config->backend_info.bSupportsShaderBinaries = true;        // Assumed support.
-  config->backend_info.bSupportsPipelineCacheData = false;    // Handled via pipeline caches.
+  config->backend_info.bSupports3DVision = false;                  // D3D-exclusive.
+  config->backend_info.bSupportsOversizedViewports = true;         // Assumed support.
+  config->backend_info.bSupportsEarlyZ = true;                     // Assumed support.
+  config->backend_info.bSupportsPrimitiveRestart = true;           // Assumed support.
+  config->backend_info.bSupportsBindingLayout = false;             // Assumed support.
+  config->backend_info.bSupportsPaletteConversion = true;          // Assumed support.
+  config->backend_info.bSupportsClipControl = true;                // Assumed support.
+  config->backend_info.bSupportsMultithreading = true;             // Assumed support.
+  config->backend_info.bSupportsComputeShaders = true;             // Assumed support.
+  config->backend_info.bSupportsGPUTextureDecoding = true;         // Assumed support.
+  config->backend_info.bSupportsBitfield = true;                   // Assumed support.
+  config->backend_info.bSupportsPartialDepthCopies = true;         // Assumed support.
+  config->backend_info.bSupportsShaderBinaries = true;             // Assumed support.
+  config->backend_info.bSupportsPipelineCacheData = false;         // Handled via pipeline caches.
   config->backend_info.bSupportsDynamicSamplerIndexing = true;     // Assumed support.
   config->backend_info.bSupportsPostProcessing = true;             // Assumed support.
   config->backend_info.bSupportsBackgroundCompiling = true;        // Assumed support.
   config->backend_info.bSupportsCopyToVram = true;                 // Assumed support.
   config->backend_info.bSupportsReversedDepthRange = true;         // Assumed support.
+  config->backend_info.bSupportsExclusiveFullscreen = false;       // Dependent on OS and features.
   config->backend_info.bSupportsDualSourceBlend = false;           // Dependent on features.
   config->backend_info.bSupportsGeometryShaders = false;           // Dependent on features.
   config->backend_info.bSupportsGSInstancing = false;              // Dependent on features.
@@ -424,7 +424,7 @@ std::unique_ptr<VulkanContext> VulkanContext::Create(VkInstance instance, VkPhys
   return context;
 }
 
-bool VulkanContext::SelectDeviceExtensions(ExtensionList* extension_list, bool enable_surface)
+bool VulkanContext::SelectDeviceExtensions(bool enable_surface)
 {
   u32 extension_count = 0;
   VkResult res =
@@ -449,14 +449,14 @@ bool VulkanContext::SelectDeviceExtensions(ExtensionList* extension_list, bool e
   for (const auto& extension_properties : available_extension_list)
     INFO_LOG(VIDEO, "Available extension: %s", extension_properties.extensionName);
 
-  auto SupportsExtension = [&](const char* name, bool required) {
+  auto AddExtension = [&](const char* name, bool required) {
     if (std::find_if(available_extension_list.begin(), available_extension_list.end(),
                      [&](const VkExtensionProperties& properties) {
                        return !strcmp(name, properties.extensionName);
                      }) != available_extension_list.end())
     {
       INFO_LOG(VIDEO, "Enabling extension: %s", name);
-      extension_list->push_back(name);
+      m_device_extensions.push_back(name);
       return true;
     }
 
@@ -466,9 +466,15 @@ bool VulkanContext::SelectDeviceExtensions(ExtensionList* extension_list, bool e
     return false;
   };
 
-  if (enable_surface && !SupportsExtension(VK_KHR_SWAPCHAIN_EXTENSION_NAME, true))
+  if (enable_surface && !AddExtension(VK_KHR_SWAPCHAIN_EXTENSION_NAME, true))
     return false;
 
+#ifdef SUPPORTS_VULKAN_EXCLUSIVE_FULLSCREEN
+  // VK_EXT_full_screen_exclusive
+  if (AddExtension(VK_EXT_FULL_SCREEN_EXCLUSIVE_EXTENSION_NAME, true))
+    INFO_LOG(VIDEO, "Using VK_EXT_full_screen_exclusive for exclusive fullscreen.");
+#endif
+
   return true;
 }
 
@@ -606,14 +612,18 @@ bool VulkanContext::CreateDevice(VkSurfaceKHR surface, bool enable_validation_la
   }
   device_info.pQueueCreateInfos = queue_infos.data();
 
-  ExtensionList enabled_extensions;
-  if (!SelectDeviceExtensions(&enabled_extensions, surface != VK_NULL_HANDLE))
+  if (!SelectDeviceExtensions(surface != VK_NULL_HANDLE))
     return false;
 
+  // convert std::string list to a char pointer list which we can feed in
+  std::vector<const char*> extension_name_pointers;
+  for (const std::string& name : m_device_extensions)
+    extension_name_pointers.push_back(name.c_str());
+
   device_info.enabledLayerCount = 0;
   device_info.ppEnabledLayerNames = nullptr;
-  device_info.enabledExtensionCount = static_cast<uint32_t>(enabled_extensions.size());
-  device_info.ppEnabledExtensionNames = enabled_extensions.data();
+  device_info.enabledExtensionCount = static_cast<uint32_t>(extension_name_pointers.size());
+  device_info.ppEnabledExtensionNames = extension_name_pointers.data();
 
   // Check for required features before creating.
   if (!SelectDeviceFeatures())
@@ -813,6 +823,12 @@ u32 VulkanContext::GetReadbackMemoryType(u32 bits, bool* is_coherent)
   return 0;
 }
 
+bool VulkanContext::SupportsDeviceExtension(const char* name) const
+{
+  return std::any_of(m_device_extensions.begin(), m_device_extensions.end(),
+                     [name](const std::string& extension) { return extension == name; });
+}
+
 void VulkanContext::InitDriverDetails()
 {
   DriverDetails::Vendor vendor;
@@ -928,4 +944,54 @@ void VulkanContext::PopulateShaderSubgroupSupport()
       (subgroup_properties.supportedOperations & required_operations) == required_operations &&
       subgroup_properties.supportedStages & VK_SHADER_STAGE_FRAGMENT_BIT;
 }
+
+bool VulkanContext::SupportsExclusiveFullscreen(const WindowSystemInfo& wsi, VkSurfaceKHR surface)
+{
+#ifdef SUPPORTS_VULKAN_EXCLUSIVE_FULLSCREEN
+  if (!surface || !vkGetPhysicalDeviceSurfaceCapabilities2KHR ||
+      !SupportsDeviceExtension(VK_EXT_FULL_SCREEN_EXCLUSIVE_EXTENSION_NAME))
+  {
+    return false;
+  }
+
+  VkPhysicalDeviceSurfaceInfo2KHR si = {};
+  si.sType = VK_STRUCTURE_TYPE_PHYSICAL_DEVICE_SURFACE_INFO_2_KHR;
+  si.surface = surface;
+
+  auto platform_info = GetPlatformExclusiveFullscreenInfo(wsi);
+  si.pNext = &platform_info;
+
+  VkSurfaceCapabilities2KHR caps = {};
+  caps.sType = VK_STRUCTURE_TYPE_SURFACE_CAPABILITIES_2_KHR;
+
+  VkSurfaceCapabilitiesFullScreenExclusiveEXT fullscreen_caps = {};
+  fullscreen_caps.sType = VK_STRUCTURE_TYPE_SURFACE_CAPABILITIES_FULL_SCREEN_EXCLUSIVE_EXT;
+  fullscreen_caps.fullScreenExclusiveSupported = VK_TRUE;
+  caps.pNext = &fullscreen_caps;
+
+  VkResult res = vkGetPhysicalDeviceSurfaceCapabilities2KHR(m_physical_device, &si, &caps);
+  if (res != VK_SUCCESS)
+  {
+    LOG_VULKAN_ERROR(res, "vkGetPhysicalDeviceSurfaceCapabilities2KHR failed:");
+    return false;
+  }
+
+  return fullscreen_caps.fullScreenExclusiveSupported;
+#else
+  return false;
+#endif
+}
+
+#ifdef WIN32
+VkSurfaceFullScreenExclusiveWin32InfoEXT
+VulkanContext::GetPlatformExclusiveFullscreenInfo(const WindowSystemInfo& wsi)
+{
+  VkSurfaceFullScreenExclusiveWin32InfoEXT info = {};
+  info.sType = VK_STRUCTURE_TYPE_SURFACE_FULL_SCREEN_EXCLUSIVE_WIN32_INFO_EXT;
+  info.hmonitor =
+      MonitorFromWindow(static_cast<HWND>(wsi.render_surface), MONITOR_DEFAULTTOPRIMARY);
+  return info;
+}
+#endif
+
 }  // namespace Vulkan
diff --git a/Source/Core/VideoBackends/Vulkan/VulkanContext.h b/Source/Core/VideoBackends/Vulkan/VulkanContext.h
index e33e5b3716..8e22daf603 100644
--- a/Source/Core/VideoBackends/Vulkan/VulkanContext.h
+++ b/Source/Core/VideoBackends/Vulkan/VulkanContext.h
@@ -6,6 +6,7 @@
 
 #include <memory>
 #include <optional>
+#include <string>
 #include <vector>
 
 #include "Common/CommonTypes.h"
@@ -107,11 +108,22 @@ public:
   u32 GetUploadMemoryType(u32 bits, bool* is_coherent = nullptr);
   u32 GetReadbackMemoryType(u32 bits, bool* is_coherent = nullptr);
 
+  // Returns true if the specified extension is supported and enabled.
+  bool SupportsDeviceExtension(const char* name) const;
+
+  // Returns true if exclusive fullscreen is supported for the given surface.
+  bool SupportsExclusiveFullscreen(const WindowSystemInfo& wsi, VkSurfaceKHR surface);
+
+#ifdef WIN32
+  // Returns the platform-specific exclusive fullscreen structure.
+  VkSurfaceFullScreenExclusiveWin32InfoEXT
+  GetPlatformExclusiveFullscreenInfo(const WindowSystemInfo& wsi);
+#endif
+
 private:
-  using ExtensionList = std::vector<const char*>;
-  static bool SelectInstanceExtensions(ExtensionList* extension_list, WindowSystemType wstype,
-                                       bool enable_debug_report);
-  bool SelectDeviceExtensions(ExtensionList* extension_list, bool enable_surface);
+  static bool SelectInstanceExtensions(std::vector<const char*>* extension_list,
+                                       WindowSystemType wstype, bool enable_debug_report);
+  bool SelectDeviceExtensions(bool enable_surface);
   bool SelectDeviceFeatures();
   bool CreateDevice(VkSurfaceKHR surface, bool enable_validation_layer);
   void InitDriverDetails();
@@ -135,6 +147,8 @@ private:
 
   u32 m_shader_subgroup_size = 1;
   bool m_supports_shader_subgroup_operations = false;
+
+  std::vector<std::string> m_device_extensions;
 };
 
 extern std::unique_ptr<VulkanContext> g_vulkan_context;
diff --git a/Source/Core/VideoBackends/Vulkan/VulkanEntryPoints.inl b/Source/Core/VideoBackends/Vulkan/VulkanEntryPoints.inl
index 874cdf9a48..97cbff969e 100644
--- a/Source/Core/VideoBackends/Vulkan/VulkanEntryPoints.inl
+++ b/Source/Core/VideoBackends/Vulkan/VulkanEntryPoints.inl
@@ -61,6 +61,7 @@ VULKAN_INSTANCE_ENTRY_POINT(vkCreateDebugReportCallbackEXT, false)
 VULKAN_INSTANCE_ENTRY_POINT(vkDestroyDebugReportCallbackEXT, false)
 VULKAN_INSTANCE_ENTRY_POINT(vkDebugReportMessageEXT, false)
 VULKAN_INSTANCE_ENTRY_POINT(vkGetPhysicalDeviceProperties2, false)
+VULKAN_INSTANCE_ENTRY_POINT(vkGetPhysicalDeviceSurfaceCapabilities2KHR, false)
 
 #endif  // VULKAN_INSTANCE_ENTRY_POINT
 
@@ -192,4 +193,9 @@ VULKAN_DEVICE_ENTRY_POINT(vkGetSwapchainImagesKHR, false)
 VULKAN_DEVICE_ENTRY_POINT(vkAcquireNextImageKHR, false)
 VULKAN_DEVICE_ENTRY_POINT(vkQueuePresentKHR, false)
 
+#ifdef SUPPORTS_VULKAN_EXCLUSIVE_FULLSCREEN
+VULKAN_DEVICE_ENTRY_POINT(vkAcquireFullScreenExclusiveModeEXT, false)
+VULKAN_DEVICE_ENTRY_POINT(vkReleaseFullScreenExclusiveModeEXT, false)
+#endif
+
 #endif  // VULKAN_DEVICE_ENTRY_POINT
diff --git a/Source/Core/VideoBackends/Vulkan/VulkanLoader.h b/Source/Core/VideoBackends/Vulkan/VulkanLoader.h
index 1bb0cae867..76fe45e037 100644
--- a/Source/Core/VideoBackends/Vulkan/VulkanLoader.h
+++ b/Source/Core/VideoBackends/Vulkan/VulkanLoader.h
@@ -24,6 +24,11 @@
 
 #include "vulkan/vulkan.h"
 
+// Currently, exclusive fullscreen is only supported on Windows.
+#if defined(WIN32)
+#define SUPPORTS_VULKAN_EXCLUSIVE_FULLSCREEN 1
+#endif
+
 // We abuse the preprocessor here to only need to specify function names once.
 #define VULKAN_MODULE_ENTRY_POINT(name, required) extern PFN_##name name;
 #define VULKAN_INSTANCE_ENTRY_POINT(name, required) extern PFN_##name name;
diff --git a/Source/Core/VideoBackends/Vulkan/main.cpp b/Source/Core/VideoBackends/Vulkan/main.cpp
index bc7ae8c067..425bcbae79 100644
--- a/Source/Core/VideoBackends/Vulkan/main.cpp
+++ b/Source/Core/VideoBackends/Vulkan/main.cpp
@@ -186,6 +186,8 @@ bool VideoBackend::Initialize(const WindowSystemInfo& wsi)
                                              g_vulkan_context->GetDeviceFeatures());
   VulkanContext::PopulateBackendInfoMultisampleModes(
       &g_Config, g_vulkan_context->GetPhysicalDevice(), g_vulkan_context->GetDeviceProperties());
+  g_Config.backend_info.bSupportsExclusiveFullscreen =
+      enable_surface && g_vulkan_context->SupportsExclusiveFullscreen(wsi, surface);
 
   // With the backend information populated, we can now initialize videocommon.
   InitializeShared();