diff --git a/CMakeLists.txt b/CMakeLists.txt
index d663a2a4a9..f4aadd64d1 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -323,7 +323,6 @@ endif(NOT GLEW_FOUND)
 if(NOT (${CMAKE_SYSTEM_NAME} MATCHES "Darwin"))
 	include_directories(Externals/CLRun/include)
 	add_subdirectory(Externals/CLRun)
-	add_definitions(-DUSE_CLRUN)
 endif()
 
 option(DISABLE_WX "Disable wxWidgets (use CLI interface)" OFF)
diff --git a/Source/Core/Common/Src/OpenCL.cpp b/Source/Core/Common/Src/OpenCL.cpp
index c1a6e7166b..2b3b309794 100644
--- a/Source/Core/Common/Src/OpenCL.cpp
+++ b/Source/Core/Common/Src/OpenCL.cpp
@@ -21,7 +21,7 @@
 #include "Common.h"
 #include "Timer.h"
 
-#if defined(_WIN32) || defined(USE_CLRUN)
+#ifndef __APPLE__
 #include "clrun.h"
 #endif
 
@@ -46,14 +46,15 @@ bool Initialize()
 		return false;
 	int err;			// error code returned from api calls
 
-#if defined(_WIN32) || defined(USE_CLRUN)
+#ifdef __APPLE__
+	// If OpenCL is weakly linked and not found, its symbols will be NULL
+	if (clGetPlatformIDs == NULL)
+		return false;
+#else
 	clrInit();
 	if(!clrHasOpenCL())
 		return false;
 #endif
-	// If OpenCL is weakly linked and not found, its symbols will be NULL
-	if (clGetPlatformIDs == NULL)
-		return false;
 
 	// Connect to a compute device
 	cl_uint numPlatforms;
diff --git a/Source/Core/Common/Src/OpenCL.h b/Source/Core/Common/Src/OpenCL.h
index a4ac241952..411a1697be 100644
--- a/Source/Core/Common/Src/OpenCL.h
+++ b/Source/Core/Common/Src/OpenCL.h
@@ -20,9 +20,8 @@
 
 #include "Common.h"
 
-// OpenCL on Windows is linked through the CLRun library
-// It provides the headers and all the imports
-#if defined(_WIN32) || defined(USE_CLRUN)
+// The CLRun library provides the headers and all the imports
+#ifndef __APPLE__
 #define HAVE_OPENCL 1
 #endif