diff --git a/Source/Core/Core/Boot/Boot_BS2Emu.cpp b/Source/Core/Core/Boot/Boot_BS2Emu.cpp
index a58abd1b64..854d71049c 100644
--- a/Source/Core/Core/Boot/Boot_BS2Emu.cpp
+++ b/Source/Core/Core/Boot/Boot_BS2Emu.cpp
@@ -166,21 +166,24 @@ bool CBoot::EmulatedBS2_GC(bool skipAppLoader)
 bool CBoot::SetupWiiMemory(DiscIO::IVolume::ECountry country)
 {
 	static const CountrySetting SETTING_EUROPE = {"EUR", "PAL",  "EU", "LE"};
+	static const CountrySetting SETTING_USA    = {"USA", "NTSC", "US", "LU"};
+	static const CountrySetting SETTING_JAPAN  = {"JPN", "NTSC", "JP", "LJ"};
+	static const CountrySetting SETTING_KOREA  = {"KOR", "NTSC", "KR", "LKH"};
 	static const std::map<DiscIO::IVolume::ECountry, const CountrySetting> country_settings = {
 		{DiscIO::IVolume::COUNTRY_EUROPE, SETTING_EUROPE},
-		{DiscIO::IVolume::COUNTRY_USA,    {"USA", "NTSC", "US", "LU"}},
-		{DiscIO::IVolume::COUNTRY_JAPAN,  {"JPN", "NTSC", "JP", "LJ"}},
-		{DiscIO::IVolume::COUNTRY_KOREA,  {"KOR", "NTSC", "KR", "LKH"}},
+		{DiscIO::IVolume::COUNTRY_USA,    SETTING_USA},
+		{DiscIO::IVolume::COUNTRY_JAPAN,  SETTING_JAPAN},
+		{DiscIO::IVolume::COUNTRY_KOREA,  SETTING_KOREA},
 		//TODO: Determine if Taiwan have their own specific settings.
 		//      Also determine if there are other specific settings
 		//      for other countries.
-		{DiscIO::IVolume::COUNTRY_TAIWAN, {"JPN", "NTSC", "JP", "LJ"}}
+		{DiscIO::IVolume::COUNTRY_TAIWAN, SETTING_JAPAN}
 	};
 	auto entryPos = country_settings.find(country);
 	const CountrySetting& country_setting =
 		(entryPos != country_settings.end()) ?
 		  entryPos->second :
-		  SETTING_EUROPE; //Default to EUROPE
+		  (SConfig::GetInstance().bNTSC ? SETTING_USA : SETTING_EUROPE); // default to USA or EUR depending on game's video mode
 
 	SettingsHandler gen;
 	std::string serno;
diff --git a/Source/Core/Core/ConfigManager.cpp b/Source/Core/Core/ConfigManager.cpp
index 577e140a3e..75f047129d 100644
--- a/Source/Core/Core/ConfigManager.cpp
+++ b/Source/Core/Core/ConfigManager.cpp
@@ -717,17 +717,21 @@ bool SConfig::AutoSetup(EBootBS2 _BootBS2)
 			else if (!strcasecmp(Extension.c_str(), ".elf"))
 			{
 				bWii = CBoot::IsElfWii(m_strFilename);
-				set_region_dir = USA_DIR;
+				// TODO: Right now GC homebrew boots in NTSC and Wii homebrew in PAL.
+				// This is intentional so that Wii homebrew can boot in both 50Hz and 60Hz, without forcing all GC homebrew to 50Hz.
+				// In the future, it probably makes sense to add a Region setting for homebrew somewhere in the emulator config.
+				bNTSC = bWii ? false : true;
+				set_region_dir = bNTSC ? USA_DIR : EUR_DIR;
 				m_BootType = BOOT_ELF;
-				bNTSC = true;
 			}
 			else if (!strcasecmp(Extension.c_str(), ".dol"))
 			{
 				CDolLoader dolfile(m_strFilename);
 				bWii = dolfile.IsWii();
-				set_region_dir = USA_DIR;
+				// TODO: See the ELF code above.
+				bNTSC = bWii ? false : true;
+				set_region_dir = bNTSC ? USA_DIR : EUR_DIR;
 				m_BootType = BOOT_DOL;
-				bNTSC = true;
 			}
 			else if (!strcasecmp(Extension.c_str(), ".dff"))
 			{