diff --git a/Source/Core/Core/Boot/Boot.cpp b/Source/Core/Core/Boot/Boot.cpp
index 618b644b38..c429b7ee2c 100644
--- a/Source/Core/Core/Boot/Boot.cpp
+++ b/Source/Core/Core/Boot/Boot.cpp
@@ -54,6 +54,12 @@
 #include "DiscIO/Enums.h"
 #include "DiscIO/Volume.h"
 
+std::vector<std::string> ReadM3UFile(const std::string& path)
+{
+  // TODO
+  return {};
+}
+
 BootParameters::BootParameters(Parameters&& parameters_,
                                const std::optional<std::string>& savestate_path_)
     : parameters(std::move(parameters_)), savestate_path(savestate_path_)
@@ -61,40 +67,68 @@ BootParameters::BootParameters(Parameters&& parameters_,
 }
 
 std::unique_ptr<BootParameters>
-BootParameters::GenerateFromFile(const std::string& path,
+BootParameters::GenerateFromFile(std::string boot_path,
                                  const std::optional<std::string>& savestate_path)
 {
-  const bool is_drive = Common::IsCDROMDevice(path);
+  return GenerateFromFile(std::vector<std::string>{std::move(boot_path)}, savestate_path);
+}
+
+std::unique_ptr<BootParameters>
+BootParameters::GenerateFromFile(std::vector<std::string> paths,
+                                 const std::optional<std::string>& savestate_path)
+{
+  ASSERT(!paths.empty());
+
+  const bool is_drive = Common::IsCDROMDevice(paths.front());
   // Check if the file exist, we may have gotten it from a --elf command line
   // that gave an incorrect file name
-  if (!is_drive && !File::Exists(path))
+  if (!is_drive && !File::Exists(paths.front()))
   {
-    PanicAlertT("The specified file \"%s\" does not exist", path.c_str());
+    PanicAlertT("The specified file \"%s\" does not exist", paths.front().c_str());
     return {};
   }
 
   std::string extension;
-  SplitPath(path, nullptr, nullptr, &extension);
+  SplitPath(paths.front(), nullptr, nullptr, &extension);
   std::transform(extension.begin(), extension.end(), extension.begin(), ::tolower);
 
+  if (extension == ".m3u")
+  {
+    std::vector<std::string> new_paths = ReadM3UFile(paths.front());
+    if (!new_paths.empty())
+    {
+      paths = new_paths;
+
+      SplitPath(paths.front(), nullptr, nullptr, &extension);
+      std::transform(extension.begin(), extension.end(), extension.begin(), ::tolower);
+    }
+  }
+
+  const std::string path = paths.front();
+  if (paths.size() == 1)
+    paths.clear();
+
   static const std::unordered_set<std::string> disc_image_extensions = {
       {".gcm", ".iso", ".tgc", ".wbfs", ".ciso", ".gcz", ".dol", ".elf"}};
   if (disc_image_extensions.find(extension) != disc_image_extensions.end() || is_drive)
   {
     std::unique_ptr<DiscIO::Volume> volume = DiscIO::CreateVolumeFromFilename(path);
     if (volume)
-      return std::make_unique<BootParameters>(Disc{path, std::move(volume)}, savestate_path);
+    {
+      return std::make_unique<BootParameters>(Disc{std::move(path), std::move(volume), paths},
+                                              savestate_path);
+    }
 
     if (extension == ".elf")
     {
-      return std::make_unique<BootParameters>(Executable{path, std::make_unique<ElfReader>(path)},
-                                              savestate_path);
+      return std::make_unique<BootParameters>(
+          Executable{std::move(path), std::make_unique<ElfReader>(path)}, savestate_path);
     }
 
     if (extension == ".dol")
     {
-      return std::make_unique<BootParameters>(Executable{path, std::make_unique<DolReader>(path)},
-                                              savestate_path);
+      return std::make_unique<BootParameters>(
+          Executable{std::move(path), std::make_unique<DolReader>(path)}, savestate_path);
     }
 
     if (is_drive)
@@ -113,10 +147,10 @@ BootParameters::GenerateFromFile(const std::string& path,
   }
 
   if (extension == ".dff")
-    return std::make_unique<BootParameters>(DFF{path}, savestate_path);
+    return std::make_unique<BootParameters>(DFF{std::move(path)}, savestate_path);
 
   if (extension == ".wad")
-    return std::make_unique<BootParameters>(DiscIO::WiiWAD{path}, savestate_path);
+    return std::make_unique<BootParameters>(DiscIO::WiiWAD{std::move(path)}, savestate_path);
 
   PanicAlertT("Could not recognize file %s", path.c_str());
   return {};
@@ -136,10 +170,11 @@ BootParameters::IPL::IPL(DiscIO::Region region_, Disc&& disc_) : IPL(region_)
 // Inserts a disc into the emulated disc drive and returns a pointer to it.
 // The returned pointer must only be used while we are still booting,
 // because DVDThread can do whatever it wants to the disc after that.
-static const DiscIO::Volume* SetDisc(std::unique_ptr<DiscIO::Volume> volume)
+static const DiscIO::Volume* SetDisc(std::unique_ptr<DiscIO::Volume> volume,
+                                     std::vector<std::string> auto_disc_change_paths = {})
 {
   const DiscIO::Volume* pointer = volume.get();
-  DVDInterface::SetDisc(std::move(volume));
+  DVDInterface::SetDisc(std::move(volume), auto_disc_change_paths);
   return pointer;
 }
 
@@ -326,7 +361,7 @@ bool CBoot::BootUp(std::unique_ptr<BootParameters> boot)
     bool operator()(BootParameters::Disc& disc) const
     {
       NOTICE_LOG(BOOT, "Booting from disc: %s", disc.path.c_str());
-      const DiscIO::Volume* volume = SetDisc(std::move(disc.volume));
+      const DiscIO::Volume* volume = SetDisc(std::move(disc.volume), disc.auto_disc_change_paths);
 
       if (!volume)
         return false;
@@ -420,7 +455,7 @@ bool CBoot::BootUp(std::unique_ptr<BootParameters> boot)
       if (ipl.disc)
       {
         NOTICE_LOG(BOOT, "Inserting disc: %s", ipl.disc->path.c_str());
-        SetDisc(DiscIO::CreateVolumeFromFilename(ipl.disc->path));
+        SetDisc(DiscIO::CreateVolumeFromFilename(ipl.disc->path), ipl.disc->auto_disc_change_paths);
       }
 
       if (LoadMapFromFilename())
diff --git a/Source/Core/Core/Boot/Boot.h b/Source/Core/Core/Boot/Boot.h
index 589b9b2056..7cb7b39989 100644
--- a/Source/Core/Core/Boot/Boot.h
+++ b/Source/Core/Core/Boot/Boot.h
@@ -40,6 +40,7 @@ struct BootParameters
   {
     std::string path;
     std::unique_ptr<DiscIO::Volume> volume;
+    std::vector<std::string> auto_disc_change_paths;
   };
 
   struct Executable
@@ -69,7 +70,9 @@ struct BootParameters
   };
 
   static std::unique_ptr<BootParameters>
-  GenerateFromFile(const std::string& boot_path,
+  GenerateFromFile(std::string boot_path, const std::optional<std::string>& savestate_path = {});
+  static std::unique_ptr<BootParameters>
+  GenerateFromFile(std::vector<std::string> paths,
                    const std::optional<std::string>& savestate_path = {});
 
   using Parameters = std::variant<Disc, Executable, DiscIO::WiiWAD, NANDTitle, IPL, DFF>;
diff --git a/Source/Core/Core/Config/MainSettings.cpp b/Source/Core/Core/Config/MainSettings.cpp
index 155c8d4933..6dc1c45eb3 100644
--- a/Source/Core/Core/Config/MainSettings.cpp
+++ b/Source/Core/Core/Config/MainSettings.cpp
@@ -104,6 +104,7 @@ const ConfigInfo<u32> MAIN_CUSTOM_RTC_VALUE{{System::Main, "Core", "CustomRTCVal
 const ConfigInfo<bool> MAIN_ENABLE_SIGNATURE_CHECKS{{System::Main, "Core", "EnableSignatureChecks"},
                                                     true};
 const ConfigInfo<bool> MAIN_REDUCE_POLLING_RATE{{System::Main, "Core", "ReducePollingRate"}, false};
+const ConfigInfo<bool> MAIN_AUTO_DISC_CHANGE{{System::Main, "Core", "AutoDiscChange"}, false};
 
 // Main.DSP
 
diff --git a/Source/Core/Core/Config/MainSettings.h b/Source/Core/Core/Config/MainSettings.h
index 65f4662bc7..d932416eb7 100644
--- a/Source/Core/Core/Config/MainSettings.h
+++ b/Source/Core/Core/Config/MainSettings.h
@@ -78,6 +78,7 @@ extern const ConfigInfo<bool> MAIN_CUSTOM_RTC_ENABLE;
 extern const ConfigInfo<u32> MAIN_CUSTOM_RTC_VALUE;
 extern const ConfigInfo<bool> MAIN_ENABLE_SIGNATURE_CHECKS;
 extern const ConfigInfo<bool> MAIN_REDUCE_POLLING_RATE;
+extern const ConfigInfo<bool> MAIN_AUTO_DISC_CHANGE;
 
 // Main.DSP
 
diff --git a/Source/Core/Core/ConfigLoaders/IsSettingSaveable.cpp b/Source/Core/Core/ConfigLoaders/IsSettingSaveable.cpp
index be51266c2f..146fdd1120 100644
--- a/Source/Core/Core/ConfigLoaders/IsSettingSaveable.cpp
+++ b/Source/Core/Core/ConfigLoaders/IsSettingSaveable.cpp
@@ -31,6 +31,7 @@ bool IsSettingSaveable(const Config::ConfigLocation& config_location)
       Config::MAIN_DEFAULT_ISO.location,
       Config::MAIN_MEMCARD_A_PATH.location,
       Config::MAIN_MEMCARD_B_PATH.location,
+      Config::MAIN_AUTO_DISC_CHANGE.location,
 
       // Graphics.Hardware
 
diff --git a/Source/Core/Core/HW/DVD/DVDInterface.cpp b/Source/Core/Core/HW/DVD/DVDInterface.cpp
index 2dda449bad..b335be618c 100644
--- a/Source/Core/Core/HW/DVD/DVDInterface.cpp
+++ b/Source/Core/Core/HW/DVD/DVDInterface.cpp
@@ -16,8 +16,10 @@
 #include "Common/Align.h"
 #include "Common/ChunkFile.h"
 #include "Common/CommonTypes.h"
+#include "Common/Config/Config.h"
 #include "Common/Logging/Log.h"
 
+#include "Core/Config/MainSettings.h"
 #include "Core/ConfigManager.h"
 #include "Core/CoreTiming.h"
 #include "Core/HW/AudioInterface.h"
@@ -36,6 +38,8 @@
 #include "DiscIO/Volume.h"
 #include "DiscIO/VolumeWii.h"
 
+#include "VideoCommon/OnScreenDisplay.h"
+
 // The minimum time it takes for the DVD drive to process a command (in
 // microseconds)
 constexpr u64 COMMAND_LATENCY_US = 300;
@@ -231,6 +235,8 @@ static u64 s_read_buffer_end_offset;
 
 // Disc changing
 static std::string s_disc_path_to_insert;
+static std::vector<std::string> s_auto_disc_change_paths;
+static size_t s_auto_disc_change_index;
 
 // Events
 static CoreTiming::EventType* s_finish_executing_command;
@@ -441,11 +447,21 @@ void Shutdown()
   DVDThread::Stop();
 }
 
-void SetDisc(std::unique_ptr<DiscIO::Volume> disc)
+void SetDisc(std::unique_ptr<DiscIO::Volume> disc,
+             std::optional<std::vector<std::string>> auto_disc_change_paths = {})
 {
   if (disc)
     s_current_partition = disc->GetGamePartition();
 
+  if (auto_disc_change_paths)
+  {
+    ASSERT_MSG(DISCIO, (*auto_disc_change_paths).size() != 1,
+               "Cannot automatically change between one disc");
+
+    s_auto_disc_change_paths = *auto_disc_change_paths;
+    s_auto_disc_change_index = 0;
+  }
+
   DVDThread::SetDisc(std::move(disc));
   SetLidOpen();
 }
@@ -457,7 +473,7 @@ bool IsDiscInside()
 
 static void EjectDiscCallback(u64 userdata, s64 cyclesLate)
 {
-  SetDisc(nullptr);
+  SetDisc(nullptr, {});
 }
 
 static void InsertDiscCallback(u64 userdata, s64 cyclesLate)
@@ -466,7 +482,7 @@ static void InsertDiscCallback(u64 userdata, s64 cyclesLate)
       DiscIO::CreateVolumeFromFilename(s_disc_path_to_insert);
 
   if (new_volume)
-    SetDisc(std::move(new_volume));
+    SetDisc(std::move(new_volume), {});
   else
     PanicAlertT("The disc that was about to be inserted couldn't be found.");
 
@@ -479,6 +495,20 @@ void EjectDisc()
   CoreTiming::ScheduleEvent(0, s_eject_disc);
 }
 
+// Must only be called on the CPU thread
+void ChangeDisc(const std::vector<std::string>& paths)
+{
+  ASSERT_MSG(DISCIO, !paths.empty(), "Trying to insert an empty list of discs");
+
+  if (paths.size() > 1)
+  {
+    s_auto_disc_change_paths = paths;
+    s_auto_disc_change_index = 0;
+  }
+
+  ChangeDisc(paths[0]);
+}
+
 // Must only be called on the CPU thread
 void ChangeDisc(const std::string& new_path)
 {
@@ -493,6 +523,28 @@ void ChangeDisc(const std::string& new_path)
   s_disc_path_to_insert = new_path;
   CoreTiming::ScheduleEvent(SystemTimers::GetTicksPerSecond(), s_insert_disc);
   Movie::SignalDiscChange(new_path);
+
+  for (size_t i = 0; i < s_auto_disc_change_paths.size(); ++i)
+  {
+    if (s_auto_disc_change_paths[i] == new_path)
+    {
+      s_auto_disc_change_index = i;
+      return;
+    }
+  }
+
+  s_auto_disc_change_paths.clear();
+}
+
+// Must only be called on the CPU thread
+bool AutoChangeDisc()
+{
+  if (s_auto_disc_change_paths.empty())
+    return false;
+
+  s_auto_disc_change_index = (s_auto_disc_change_index + 1) % s_auto_disc_change_paths.size();
+  ChangeDisc(s_auto_disc_change_paths[s_auto_disc_change_index]);
+  return true;
 }
 
 void SetLidOpen()
@@ -983,12 +1035,20 @@ void ExecuteCommand(u32 command_0, u32 command_1, u32 command_2, u32 output_addr
   break;
 
   case DVDLowStopMotor:
+  {
     INFO_LOG(DVDINTERFACE, "DVDLowStopMotor %s %s", command_1 ? "eject" : "",
              command_2 ? "kill!" : "");
 
-    if (command_1 && !command_2)
+    bool auto_disc_change = Config::Get(Config::MAIN_AUTO_DISC_CHANGE) && !Movie::IsPlayingInput();
+    if (auto_disc_change)
+      auto_disc_change = AutoChangeDisc();
+    if (auto_disc_change)
+      OSD::AddMessage("Changing discs automatically...", OSD::Duration::NORMAL);
+
+    if (!auto_disc_change && command_1 && !command_2)
       EjectDiscCallback(0, 0);
     break;
+  }
 
   // DVD Audio Enable/Disable (Immediate). GC uses this, and apparently Wii also does...?
   case DVDLowAudioBufferConfig:
diff --git a/Source/Core/Core/HW/DVD/DVDInterface.h b/Source/Core/Core/HW/DVD/DVDInterface.h
index fc23fb8bbd..e345dd07a6 100644
--- a/Source/Core/Core/HW/DVD/DVDInterface.h
+++ b/Source/Core/Core/HW/DVD/DVDInterface.h
@@ -111,10 +111,13 @@ void DoState(PointerWrap& p);
 
 void RegisterMMIO(MMIO::Mapping* mmio, u32 base);
 
-void SetDisc(std::unique_ptr<DiscIO::Volume> disc);
+void SetDisc(std::unique_ptr<DiscIO::Volume> disc,
+             std::optional<std::vector<std::string>> auto_disc_change_paths);
 bool IsDiscInside();
-void EjectDisc();                              // Must only be called on the CPU thread
-void ChangeDisc(const std::string& new_path);  // Must only be called on the CPU thread
+void EjectDisc();                                        // Must only be called on the CPU thread
+void ChangeDisc(const std::vector<std::string>& paths);  // Must only be called on the CPU thread
+void ChangeDisc(const std::string& new_path);            // Must only be called on the CPU thread
+bool AutoChangeDisc();                                   // Must only be called on the CPU thread
 
 // This function returns true and calls SConfig::SetRunningGameMetadata(Volume&, Partition&)
 // if both of the following conditions are true:
diff --git a/Source/Core/Core/Movie.cpp b/Source/Core/Core/Movie.cpp
index d779f0a71d..ae12021e47 100644
--- a/Source/Core/Core/Movie.cpp
+++ b/Source/Core/Core/Movie.cpp
@@ -1176,29 +1176,13 @@ void PlayController(GCPadStatus* PadStatus, int controllerID)
     PadStatus->button |= PAD_TRIGGER_R;
   if (s_padState.disc)
   {
-    // This implementation assumes the disc change will only happen once. Trying
-    // to change more than that will cause it to load the last disc every time.
-    // As far as I know, there are no 3+ disc games, so this should be fine.
-    bool found = false;
-    std::string path;
-    for (const std::string& iso_folder : SConfig::GetInstance().m_ISOFolder)
-    {
-      path = iso_folder + '/' + s_discChange;
-      if (File::Exists(path))
+    Core::RunAsCPUThread([] {
+      if (!DVDInterface::AutoChangeDisc())
       {
-        found = true;
-        break;
+        CPU::Break();
+        PanicAlertT("Change the disc to %s", s_discChange.c_str());
       }
-    }
-    if (found)
-    {
-      Core::RunAsCPUThread([&path] { DVDInterface::ChangeDisc(path); });
-    }
-    else
-    {
-      CPU::Break();
-      PanicAlertT("Change the disc to %s", s_discChange.c_str());
-    }
+    });
   }
 
   if (s_padState.reset)
diff --git a/Source/Core/DolphinNoGUI/MainNoGUI.cpp b/Source/Core/DolphinNoGUI/MainNoGUI.cpp
index 6cd71bd353..697e4cbe6d 100644
--- a/Source/Core/DolphinNoGUI/MainNoGUI.cpp
+++ b/Source/Core/DolphinNoGUI/MainNoGUI.cpp
@@ -368,7 +368,10 @@ int main(int argc, char* argv[])
   std::unique_ptr<BootParameters> boot;
   if (options.is_set("exec"))
   {
-    boot = BootParameters::GenerateFromFile(static_cast<const char*>(options.get("exec")));
+    const std::list<std::string> paths_list = options.all("exec");
+    const std::vector<std::string> paths{std::make_move_iterator(std::begin(paths_list)),
+                                         std::make_move_iterator(std::end(paths_list))};
+    boot = BootParameters::GenerateFromFile(paths);
   }
   else if (options.is_set("nand_title"))
   {
diff --git a/Source/Core/DolphinQt/GameList/GameList.cpp b/Source/Core/DolphinQt/GameList/GameList.cpp
index c2a098281f..0af57f92ba 100644
--- a/Source/Core/DolphinQt/GameList/GameList.cpp
+++ b/Source/Core/DolphinQt/GameList/GameList.cpp
@@ -737,6 +737,17 @@ bool GameList::HasMultipleSelected() const
                                      m_grid->selectionModel()->selectedIndexes().size() > 1;
 }
 
+std::shared_ptr<const UICommon::GameFile> GameList::FindGame(const std::string& path) const
+{
+  return m_model->FindGame(path);
+}
+
+std::shared_ptr<const UICommon::GameFile>
+GameList::FindSecondDisc(const UICommon::GameFile& game) const
+{
+  return m_model->FindSecondDisc(game);
+}
+
 void GameList::SetViewColumn(int col, bool view)
 {
   m_list->setColumnHidden(col, !view);
diff --git a/Source/Core/DolphinQt/GameList/GameList.h b/Source/Core/DolphinQt/GameList/GameList.h
index fac9932c3c..e7782651be 100644
--- a/Source/Core/DolphinQt/GameList/GameList.h
+++ b/Source/Core/DolphinQt/GameList/GameList.h
@@ -30,6 +30,8 @@ public:
   std::shared_ptr<const UICommon::GameFile> GetSelectedGame() const;
   QList<std::shared_ptr<const UICommon::GameFile>> GetSelectedGames() const;
   bool HasMultipleSelected() const;
+  std::shared_ptr<const UICommon::GameFile> FindGame(const std::string& path) const;
+  std::shared_ptr<const UICommon::GameFile> FindSecondDisc(const UICommon::GameFile& game) const;
 
   void SetListView() { SetPreferredView(true); }
   void SetGridView() { SetPreferredView(false); }
diff --git a/Source/Core/DolphinQt/GameList/GameListModel.cpp b/Source/Core/DolphinQt/GameList/GameListModel.cpp
index 43bc61f9a1..e7440ce1e2 100644
--- a/Source/Core/DolphinQt/GameList/GameListModel.cpp
+++ b/Source/Core/DolphinQt/GameList/GameListModel.cpp
@@ -278,7 +278,7 @@ void GameListModel::AddGame(const std::shared_ptr<const UICommon::GameFile>& gam
 
 void GameListModel::UpdateGame(const std::shared_ptr<const UICommon::GameFile>& game)
 {
-  int index = FindGame(game->GetFilePath());
+  int index = FindGameIndex(game->GetFilePath());
   if (index < 0)
   {
     AddGame(game);
@@ -292,7 +292,7 @@ void GameListModel::UpdateGame(const std::shared_ptr<const UICommon::GameFile>&
 
 void GameListModel::RemoveGame(const std::string& path)
 {
-  int entry = FindGame(path);
+  int entry = FindGameIndex(path);
   if (entry < 0)
     return;
 
@@ -301,7 +301,13 @@ void GameListModel::RemoveGame(const std::string& path)
   endRemoveRows();
 }
 
-int GameListModel::FindGame(const std::string& path) const
+std::shared_ptr<const UICommon::GameFile> GameListModel::FindGame(const std::string& path) const
+{
+  const int index = FindGameIndex(path);
+  return index < 0 ? nullptr : m_games[index];
+}
+
+int GameListModel::FindGameIndex(const std::string& path) const
 {
   for (int i = 0; i < m_games.size(); i++)
   {
@@ -311,6 +317,29 @@ int GameListModel::FindGame(const std::string& path) const
   return -1;
 }
 
+std::shared_ptr<const UICommon::GameFile>
+GameListModel::FindSecondDisc(const UICommon::GameFile& game) const
+{
+  std::shared_ptr<const UICommon::GameFile> match_without_revision = nullptr;
+
+  if (DiscIO::IsDisc(game.GetPlatform()))
+  {
+    for (auto& other_game : m_games)
+    {
+      if (game.GetGameID() == other_game->GetGameID() &&
+          game.GetDiscNumber() != other_game->GetDiscNumber())
+      {
+        if (game.GetRevision() == other_game->GetRevision())
+          return other_game;
+        else
+          match_without_revision = other_game;
+      }
+    }
+  }
+
+  return match_without_revision;
+}
+
 void GameListModel::SetSearchTerm(const QString& term)
 {
   m_term = term;
diff --git a/Source/Core/DolphinQt/GameList/GameListModel.h b/Source/Core/DolphinQt/GameList/GameListModel.h
index 7defb3f9cb..de0501d53b 100644
--- a/Source/Core/DolphinQt/GameList/GameListModel.h
+++ b/Source/Core/DolphinQt/GameList/GameListModel.h
@@ -63,6 +63,9 @@ public:
   void UpdateGame(const std::shared_ptr<const UICommon::GameFile>& game);
   void RemoveGame(const std::string& path);
 
+  std::shared_ptr<const UICommon::GameFile> FindGame(const std::string& path) const;
+  std::shared_ptr<const UICommon::GameFile> FindSecondDisc(const UICommon::GameFile& game) const;
+
   void SetScale(float scale);
   float GetScale() const;
 
@@ -79,7 +82,7 @@ public:
 
 private:
   // Index in m_games, or -1 if it isn't found
-  int FindGame(const std::string& path) const;
+  int FindGameIndex(const std::string& path) const;
 
   QStringList m_tag_list;
   QMap<QString, QVariant> m_game_tags;
diff --git a/Source/Core/DolphinQt/Main.cpp b/Source/Core/DolphinQt/Main.cpp
index 4c7aa086ff..5ca745e874 100644
--- a/Source/Core/DolphinQt/Main.cpp
+++ b/Source/Core/DolphinQt/Main.cpp
@@ -147,7 +147,10 @@ int main(int argc, char* argv[])
   std::unique_ptr<BootParameters> boot;
   if (options.is_set("exec"))
   {
-    boot = BootParameters::GenerateFromFile(static_cast<const char*>(options.get("exec")));
+    const std::list<std::string> paths_list = options.all("exec");
+    const std::vector<std::string> paths{std::make_move_iterator(std::begin(paths_list)),
+                                         std::make_move_iterator(std::end(paths_list))};
+    boot = BootParameters::GenerateFromFile(paths);
   }
   else if (options.is_set("nand_title"))
   {
diff --git a/Source/Core/DolphinQt/MainWindow.cpp b/Source/Core/DolphinQt/MainWindow.cpp
index 1b57cbe96c..ed4379ea98 100644
--- a/Source/Core/DolphinQt/MainWindow.cpp
+++ b/Source/Core/DolphinQt/MainWindow.cpp
@@ -168,6 +168,17 @@ static WindowSystemInfo GetWindowSystemInfo(QWindow* window)
   return wsi;
 }
 
+static std::vector<std::string> StringListToStdVector(QStringList list)
+{
+  std::vector<std::string> result;
+  result.reserve(list.size());
+
+  for (const QString& s : list)
+    result.push_back(s.toStdString());
+
+  return result;
+}
+
 MainWindow::MainWindow(std::unique_ptr<BootParameters> boot_parameters) : QMainWindow(nullptr)
 {
   setWindowTitle(QString::fromStdString(Common::scm_rev_str));
@@ -387,7 +398,7 @@ void MainWindow::ConnectMenuBar()
   connect(m_menu_bar, &MenuBar::EjectDisc, this, &MainWindow::EjectDisc);
   connect(m_menu_bar, &MenuBar::ChangeDisc, this, &MainWindow::ChangeDisc);
   connect(m_menu_bar, &MenuBar::BootDVDBackup, this,
-          [this](const QString& drive) { StartGame(drive); });
+          [this](const QString& drive) { StartGame(drive, ScanForSecondDisc::No); });
 
   // Emulation
   connect(m_menu_bar, &MenuBar::Pause, this, &MainWindow::Pause);
@@ -610,30 +621,30 @@ void MainWindow::RefreshGameList()
   Settings::Instance().RefreshGameList();
 }
 
-QString MainWindow::PromptFileName()
+QStringList MainWindow::PromptFileNames()
 {
   auto& settings = Settings::Instance().GetQSettings();
-  QString path = QFileDialog::getOpenFileName(
+  QStringList paths = QFileDialog::getOpenFileNames(
       this, tr("Select a File"),
       settings.value(QStringLiteral("mainwindow/lastdir"), QStringLiteral("")).toString(),
       tr("All GC/Wii files (*.elf *.dol *.gcm *.iso *.tgc *.wbfs *.ciso *.gcz *.wad *.dff);;"
          "All Files (*)"));
 
-  if (!path.isEmpty())
+  if (!paths.isEmpty())
   {
     settings.setValue(QStringLiteral("mainwindow/lastdir"),
-                      QFileInfo(path).absoluteDir().absolutePath());
+                      QFileInfo(paths.front()).absoluteDir().absolutePath());
   }
 
-  return path;
+  return paths;
 }
 
 void MainWindow::ChangeDisc()
 {
-  QString file = PromptFileName();
+  std::vector<std::string> paths = StringListToStdVector(PromptFileNames());
 
-  if (!file.isEmpty())
-    Core::RunAsCPUThread([&file] { DVDInterface::ChangeDisc(file.toStdString()); });
+  if (!paths.empty())
+    Core::RunAsCPUThread([&paths] { DVDInterface::ChangeDisc(paths); });
 }
 
 void MainWindow::EjectDisc()
@@ -643,9 +654,9 @@ void MainWindow::EjectDisc()
 
 void MainWindow::Open()
 {
-  QString file = PromptFileName();
-  if (!file.isEmpty())
-    StartGame(file);
+  QStringList files = PromptFileNames();
+  if (!files.isEmpty())
+    StartGame(StringListToStdVector(files));
 }
 
 void MainWindow::Play(const std::optional<std::string>& savestate_path)
@@ -664,7 +675,7 @@ void MainWindow::Play(const std::optional<std::string>& savestate_path)
     std::shared_ptr<const UICommon::GameFile> selection = m_game_list->GetSelectedGame();
     if (selection)
     {
-      StartGame(selection->GetFilePath(), savestate_path);
+      StartGame(selection->GetFilePath(), ScanForSecondDisc::Yes, savestate_path);
       EnableScreenSaver(false);
     }
     else
@@ -672,7 +683,7 @@ void MainWindow::Play(const std::optional<std::string>& savestate_path)
       const QString default_path = QString::fromStdString(Config::Get(Config::MAIN_DEFAULT_ISO));
       if (!default_path.isEmpty() && QFile::exists(default_path))
       {
-        StartGame(default_path, savestate_path);
+        StartGame(default_path, ScanForSecondDisc::Yes, savestate_path);
         EnableScreenSaver(false);
       }
       else
@@ -833,17 +844,46 @@ void MainWindow::ScreenShot()
   Core::SaveScreenShot();
 }
 
-void MainWindow::StartGame(const QString& path, const std::optional<std::string>& savestate_path)
+void MainWindow::ScanForSecondDiscAndStartGame(const UICommon::GameFile& game,
+                                               const std::optional<std::string>& savestate_path)
 {
-  StartGame(path.toStdString(), savestate_path);
+  auto second_game = m_game_list->FindSecondDisc(game);
+
+  std::vector<std::string> paths = {game.GetFilePath()};
+  if (second_game != nullptr)
+    paths.push_back(second_game->GetFilePath());
+
+  StartGame(paths, savestate_path);
 }
 
-void MainWindow::StartGame(const std::string& path,
+void MainWindow::StartGame(const QString& path, ScanForSecondDisc scan,
                            const std::optional<std::string>& savestate_path)
 {
+  StartGame(path.toStdString(), scan, savestate_path);
+}
+
+void MainWindow::StartGame(const std::string& path, ScanForSecondDisc scan,
+                           const std::optional<std::string>& savestate_path)
+{
+  if (scan == ScanForSecondDisc::Yes)
+  {
+    std::shared_ptr<const UICommon::GameFile> game = m_game_list->FindGame(path);
+    if (game != nullptr)
+    {
+      ScanForSecondDiscAndStartGame(*game, savestate_path);
+      return;
+    }
+  }
+
   StartGame(BootParameters::GenerateFromFile(path, savestate_path));
 }
 
+void MainWindow::StartGame(const std::vector<std::string>& paths,
+                           const std::optional<std::string>& savestate_path)
+{
+  StartGame(BootParameters::GenerateFromFile(paths, savestate_path));
+}
+
 void MainWindow::StartGame(std::unique_ptr<BootParameters>&& parameters)
 {
   // If we're running, only start a new game once we've stopped the last.
@@ -1075,7 +1115,7 @@ void MainWindow::ShowFIFOPlayer()
   {
     m_fifo_window = new FIFOPlayerWindow(this);
     connect(m_fifo_window, &FIFOPlayerWindow::LoadFIFORequested, this,
-            [this](const QString& path) { StartGame(path); });
+            [this](const QString& path) { StartGame(path, ScanForSecondDisc::No); });
   }
 
   m_fifo_window->show();
@@ -1170,7 +1210,7 @@ void MainWindow::NetPlayInit()
 #endif
 
   connect(m_netplay_dialog, &NetPlayDialog::Boot, this,
-          [this](const QString& path) { StartGame(path); });
+          [this](const QString& path) { StartGame(path, ScanForSecondDisc::Yes); });
   connect(m_netplay_dialog, &NetPlayDialog::Stop, this, &MainWindow::ForceStop);
   connect(m_netplay_dialog, &NetPlayDialog::rejected, this, &MainWindow::NetPlayQuit);
   connect(m_netplay_setup_dialog, &NetPlaySetupDialog::Join, this, &MainWindow::NetPlayJoin);
@@ -1346,38 +1386,48 @@ void MainWindow::dragEnterEvent(QDragEnterEvent* event)
 
 void MainWindow::dropEvent(QDropEvent* event)
 {
-  const auto& urls = event->mimeData()->urls();
+  const QList<QUrl>& urls = event->mimeData()->urls();
   if (urls.empty())
     return;
 
-  const auto& url = urls[0];
-  QFileInfo file_info(url.toLocalFile());
+  QStringList files;
+  QStringList folders;
 
-  auto path = file_info.filePath();
-
-  if (!file_info.exists() || !file_info.isReadable())
+  for (const QUrl& url : urls)
   {
-    QMessageBox::critical(this, tr("Error"), tr("Failed to open '%1'").arg(path));
-    return;
+    QFileInfo file_info(url.toLocalFile());
+    QString path = file_info.filePath();
+
+    if (!file_info.exists() || !file_info.isReadable())
+    {
+      QMessageBox::critical(this, tr("Error"), tr("Failed to open '%1'").arg(path));
+      return;
+    }
+
+    (file_info.isFile() ? files : folders).append(path);
   }
 
-  if (file_info.isFile())
+  if (!files.isEmpty())
   {
-    StartGame(path);
+    StartGame(StringListToStdVector(files));
   }
   else
   {
-    auto& settings = Settings::Instance();
+    Settings& settings = Settings::Instance();
+    const bool show_confirm = settings.GetPaths().size() != 0;
 
-    if (settings.GetPaths().size() != 0)
+    for (const QString& folder : folders)
     {
-      if (QMessageBox::question(
-              this, tr("Confirm"),
-              tr("Do you want to add \"%1\" to the list of Game Paths?").arg(path)) !=
-          QMessageBox::Yes)
-        return;
+      if (show_confirm)
+      {
+        if (QMessageBox::question(
+                this, tr("Confirm"),
+                tr("Do you want to add \"%1\" to the list of Game Paths?").arg(folder)) !=
+            QMessageBox::Yes)
+          return;
+      }
+      settings.AddPath(folder);
     }
-    settings.AddPath(path);
   }
 }
 
diff --git a/Source/Core/DolphinQt/MainWindow.h b/Source/Core/DolphinQt/MainWindow.h
index 30c29030db..4c5224fb6a 100644
--- a/Source/Core/DolphinQt/MainWindow.h
+++ b/Source/Core/DolphinQt/MainWindow.h
@@ -5,6 +5,7 @@
 #pragma once
 
 #include <QMainWindow>
+#include <QStringList>
 
 #include <memory>
 #include <optional>
@@ -47,6 +48,11 @@ namespace DiscIO
 enum class Region;
 }
 
+namespace UICommon
+{
+class GameFile;
+}
+
 namespace X11Utils
 {
 class XRRConfiguration;
@@ -115,8 +121,20 @@ private:
 
   void InitCoreCallbacks();
 
-  void StartGame(const QString& path, const std::optional<std::string>& savestate_path = {});
-  void StartGame(const std::string& path, const std::optional<std::string>& savestate_path = {});
+  enum class ScanForSecondDisc
+  {
+    Yes,
+    No,
+  };
+
+  void ScanForSecondDiscAndStartGame(const UICommon::GameFile& game,
+                                     const std::optional<std::string>& savestate_path = {});
+  void StartGame(const QString& path, ScanForSecondDisc scan,
+                 const std::optional<std::string>& savestate_path = {});
+  void StartGame(const std::string& path, ScanForSecondDisc scan,
+                 const std::optional<std::string>& savestate_path = {});
+  void StartGame(const std::vector<std::string>& paths,
+                 const std::optional<std::string>& savestate_path = {});
   void StartGame(std::unique_ptr<BootParameters>&& parameters);
   void ShowRenderWidget();
   void HideRenderWidget(bool reinit = true);
@@ -155,7 +173,7 @@ private:
   void ChangeDisc();
   void EjectDisc();
 
-  QString PromptFileName();
+  QStringList PromptFileNames();
 
   void EnableScreenSaver(bool enable);
 
diff --git a/Source/Core/DolphinQt/Settings/GeneralPane.cpp b/Source/Core/DolphinQt/Settings/GeneralPane.cpp
index d98d5cb04e..78ec034fb3 100644
--- a/Source/Core/DolphinQt/Settings/GeneralPane.cpp
+++ b/Source/Core/DolphinQt/Settings/GeneralPane.cpp
@@ -96,6 +96,7 @@ void GeneralPane::ConnectLayout()
 {
   connect(m_checkbox_dualcore, &QCheckBox::toggled, this, &GeneralPane::OnSaveConfig);
   connect(m_checkbox_cheats, &QCheckBox::toggled, this, &GeneralPane::OnSaveConfig);
+  connect(m_checkbox_auto_disc_change, &QCheckBox::toggled, this, &GeneralPane::OnSaveConfig);
 #ifdef USE_DISCORD_PRESENCE
   connect(m_checkbox_discord_presence, &QCheckBox::toggled, this, &GeneralPane::OnSaveConfig);
 #endif
@@ -137,6 +138,9 @@ void GeneralPane::CreateBasic()
   m_checkbox_cheats = new QCheckBox(tr("Enable Cheats"));
   basic_group_layout->addWidget(m_checkbox_cheats);
 
+  m_checkbox_auto_disc_change = new QCheckBox(tr("Change Discs Automatically"));
+  basic_group_layout->addWidget(m_checkbox_auto_disc_change);
+
 #ifdef USE_DISCORD_PRESENCE
   m_checkbox_discord_presence = new QCheckBox(tr("Show Current Game on Discord"));
   basic_group_layout->addWidget(m_checkbox_discord_presence);
@@ -236,6 +240,7 @@ void GeneralPane::LoadConfig()
 #endif
   m_checkbox_dualcore->setChecked(SConfig::GetInstance().bCPUThread);
   m_checkbox_cheats->setChecked(Settings::Instance().GetCheatsEnabled());
+  m_checkbox_auto_disc_change->setChecked(Config::Get(Config::MAIN_AUTO_DISC_CHANGE));
 #ifdef USE_DISCORD_PRESENCE
   m_checkbox_discord_presence->setChecked(Config::Get(Config::MAIN_USE_DISCORD_PRESENCE));
 #endif
@@ -295,6 +300,7 @@ void GeneralPane::OnSaveConfig()
   settings.bCPUThread = m_checkbox_dualcore->isChecked();
   Config::SetBaseOrCurrent(Config::MAIN_CPU_THREAD, m_checkbox_dualcore->isChecked());
   Settings::Instance().SetCheatsEnabled(m_checkbox_cheats->isChecked());
+  Config::SetBase(Config::MAIN_AUTO_DISC_CHANGE, m_checkbox_auto_disc_change->isChecked());
   Config::SetBaseOrCurrent(Config::MAIN_ENABLE_CHEATS, m_checkbox_cheats->isChecked());
   settings.m_EmulationSpeed = m_combobox_speedlimit->currentIndex() * 0.1f;
 
diff --git a/Source/Core/DolphinQt/Settings/GeneralPane.h b/Source/Core/DolphinQt/Settings/GeneralPane.h
index 90d53838e7..9ae0d48893 100644
--- a/Source/Core/DolphinQt/Settings/GeneralPane.h
+++ b/Source/Core/DolphinQt/Settings/GeneralPane.h
@@ -44,6 +44,7 @@ private:
   QComboBox* m_combobox_update_track;
   QCheckBox* m_checkbox_dualcore;
   QCheckBox* m_checkbox_cheats;
+  QCheckBox* m_checkbox_auto_disc_change;
 #ifdef USE_DISCORD_PRESENCE
   QCheckBox* m_checkbox_discord_presence;
 #endif
diff --git a/Source/Core/UICommon/CommandLineParse.cpp b/Source/Core/UICommon/CommandLineParse.cpp
index bc8da4d92b..69f1491ad7 100644
--- a/Source/Core/UICommon/CommandLineParse.cpp
+++ b/Source/Core/UICommon/CommandLineParse.cpp
@@ -75,7 +75,7 @@ std::unique_ptr<optparse::OptionParser> CreateParser(ParserOptions options)
   parser->add_option("-u", "--user").action("store").help("User folder path");
   parser->add_option("-m", "--movie").action("store").help("Play a movie file");
   parser->add_option("-e", "--exec")
-      .action("store")
+      .action("append")
       .metavar("<file>")
       .type("string")
       .help("Load the specified file");