diff --git a/Source/Core/Core/HW/Memmap.cpp b/Source/Core/Core/HW/Memmap.cpp
index 789ce66386..47028c7194 100644
--- a/Source/Core/Core/HW/Memmap.cpp
+++ b/Source/Core/Core/HW/Memmap.cpp
@@ -9,6 +9,7 @@
 // may be redirected here (for example to Read_U32()).
 
 #include <cstring>
+#include <memory>
 
 #include "Common/ChunkFile.h"
 #include "Common/CommonFuncs.h"
@@ -58,31 +59,37 @@ u8* m_pEXRAM;
 u8* m_pFakeVMEM;
 
 // MMIO mapping object.
-MMIO::Mapping* mmio_mapping;
+std::unique_ptr<MMIO::Mapping> mmio_mapping;
 
-static void InitMMIO(MMIO::Mapping* mmio)
+static std::unique_ptr<MMIO::Mapping> InitMMIO()
 {
-	CommandProcessor::RegisterMMIO(mmio, 0x0C000000);
-	PixelEngine::RegisterMMIO(mmio, 0x0C001000);
-	VideoInterface::RegisterMMIO(mmio, 0x0C002000);
-	ProcessorInterface::RegisterMMIO(mmio, 0x0C003000);
-	MemoryInterface::RegisterMMIO(mmio, 0x0C004000);
-	DSP::RegisterMMIO(mmio, 0x0C005000);
-	DVDInterface::RegisterMMIO(mmio, 0x0C006000);
-	SerialInterface::RegisterMMIO(mmio, 0x0C006400);
-	ExpansionInterface::RegisterMMIO(mmio, 0x0C006800);
-	AudioInterface::RegisterMMIO(mmio, 0x0C006C00);
+	auto mmio = std::make_unique<MMIO::Mapping>();
+
+	CommandProcessor  ::RegisterMMIO(mmio.get(), 0x0C000000);
+	PixelEngine       ::RegisterMMIO(mmio.get(), 0x0C001000);
+	VideoInterface    ::RegisterMMIO(mmio.get(), 0x0C002000);
+	ProcessorInterface::RegisterMMIO(mmio.get(), 0x0C003000);
+	MemoryInterface   ::RegisterMMIO(mmio.get(), 0x0C004000);
+	DSP               ::RegisterMMIO(mmio.get(), 0x0C005000);
+	DVDInterface      ::RegisterMMIO(mmio.get(), 0x0C006000);
+	SerialInterface   ::RegisterMMIO(mmio.get(), 0x0C006400);
+	ExpansionInterface::RegisterMMIO(mmio.get(), 0x0C006800);
+	AudioInterface    ::RegisterMMIO(mmio.get(), 0x0C006C00);
+
+	return mmio;
 }
 
-static void InitMMIOWii(MMIO::Mapping* mmio)
+static std::unique_ptr<MMIO::Mapping> InitMMIOWii()
 {
-	InitMMIO(mmio);
+	auto mmio = InitMMIO();
 
-	WII_IPCInterface::RegisterMMIO(mmio, 0x0D000000);
-	DVDInterface::RegisterMMIO(mmio, 0x0D006000);
-	SerialInterface::RegisterMMIO(mmio, 0x0D006400);
-	ExpansionInterface::RegisterMMIO(mmio, 0x0D006800);
-	AudioInterface::RegisterMMIO(mmio, 0x0D006C00);
+	WII_IPCInterface  ::RegisterMMIO(mmio.get(), 0x0D000000);
+	DVDInterface      ::RegisterMMIO(mmio.get(), 0x0D006000);
+	SerialInterface   ::RegisterMMIO(mmio.get(), 0x0D006400);
+	ExpansionInterface::RegisterMMIO(mmio.get(), 0x0D006800);
+	AudioInterface    ::RegisterMMIO(mmio.get(), 0x0D006C00);
+
+	return mmio;
 }
 
 bool IsInitialized()
@@ -180,12 +187,10 @@ void Init()
 	logical_base = physical_base + 0x200000000;
 #endif
 
-	mmio_mapping = new MMIO::Mapping();
-
 	if (wii)
-		InitMMIOWii(mmio_mapping);
+		mmio_mapping = InitMMIOWii();
 	else
-		InitMMIO(mmio_mapping);
+		mmio_mapping = InitMMIO();
 
 	INFO_LOG(MEMMAP, "Memory system initialized. RAM at %p", m_pRAM);
 	m_IsInitialized = true;
@@ -215,7 +220,7 @@ void Shutdown()
 	g_arena.ReleaseSHMSegment();
 	physical_base = nullptr;
 	logical_base = nullptr;
-	delete mmio_mapping;
+	mmio_mapping.reset();
 	INFO_LOG(MEMMAP, "Memory system shut down.");
 }
 
diff --git a/Source/Core/Core/HW/Memmap.h b/Source/Core/Core/HW/Memmap.h
index 69701814e7..a1e5240b06 100644
--- a/Source/Core/Core/HW/Memmap.h
+++ b/Source/Core/Core/HW/Memmap.h
@@ -4,6 +4,7 @@
 
 #pragma once
 
+#include <memory>
 #include <string>
 
 #include "Common/CommonFuncs.h"
@@ -63,7 +64,7 @@ enum
 };
 
 // MMIO mapping object.
-extern MMIO::Mapping* mmio_mapping;
+extern std::unique_ptr<MMIO::Mapping> mmio_mapping;
 
 // Init and Shutdown
 bool IsInitialized();
diff --git a/Source/Core/Core/PowerPC/JitArm64/JitArm64_LoadStore.cpp b/Source/Core/Core/PowerPC/JitArm64/JitArm64_LoadStore.cpp
index d5f8f4747a..b9f130394a 100644
--- a/Source/Core/Core/PowerPC/JitArm64/JitArm64_LoadStore.cpp
+++ b/Source/Core/Core/PowerPC/JitArm64/JitArm64_LoadStore.cpp
@@ -154,7 +154,7 @@ void JitArm64::SafeLoadToReg(u32 dest, s32 addr, s32 offsetReg, u32 flags, s32 o
 	}
 	else if (mmio_address)
 	{
-		MMIOLoadToReg(Memory::mmio_mapping, this,
+		MMIOLoadToReg(Memory::mmio_mapping.get(), this,
 		              regs_in_use, fprs_in_use, dest_reg,
 		              mmio_address, flags);
 	}
@@ -350,7 +350,7 @@ void JitArm64::SafeStoreFromReg(s32 dest, u32 value, s32 regOffset, u32 flags, s
 	}
 	else if (mmio_address && !(flags & BackPatchInfo::FLAG_REVERSE))
 	{
-		MMIOWriteRegToAddr(Memory::mmio_mapping, this,
+		MMIOWriteRegToAddr(Memory::mmio_mapping.get(), this,
 		                   regs_in_use, fprs_in_use, RS,
 		                   mmio_address, flags);
 	}
diff --git a/Source/Core/Core/PowerPC/JitCommon/Jit_Util.cpp b/Source/Core/Core/PowerPC/JitCommon/Jit_Util.cpp
index 11a02efb31..51549c69f2 100644
--- a/Source/Core/Core/PowerPC/JitCommon/Jit_Util.cpp
+++ b/Source/Core/Core/PowerPC/JitCommon/Jit_Util.cpp
@@ -264,7 +264,7 @@ void EmuCodeBlock::SafeLoadToReg(X64Reg reg_value, const Gen::OpArg & opAddress,
 		u32 mmioAddress = PowerPC::IsOptimizableMMIOAccess(address, accessSize);
 		if (accessSize != 64 && mmioAddress)
 		{
-			MMIOLoadToReg(Memory::mmio_mapping, reg_value, registersInUse,
+			MMIOLoadToReg(Memory::mmio_mapping.get(), reg_value, registersInUse,
 			              mmioAddress, accessSize, signExtend);
 			return;
 		}