diff --git a/Source/Android/app/src/main/java/org/dolphinemu/dolphinemu/features/settings/ui/viewholder/SettingViewHolder.java b/Source/Android/app/src/main/java/org/dolphinemu/dolphinemu/features/settings/ui/viewholder/SettingViewHolder.java
index 611a62ca13..d34e4a1536 100644
--- a/Source/Android/app/src/main/java/org/dolphinemu/dolphinemu/features/settings/ui/viewholder/SettingViewHolder.java
+++ b/Source/Android/app/src/main/java/org/dolphinemu/dolphinemu/features/settings/ui/viewholder/SettingViewHolder.java
@@ -54,6 +54,12 @@ public abstract class SettingViewHolder extends RecyclerView.ViewHolder
             Toast.LENGTH_SHORT).show();
   }
 
+  protected static void showIplNotAvailableError()
+  {
+    Toast.makeText(DolphinApplication.getAppContext(), R.string.ipl_not_found, Toast.LENGTH_SHORT)
+            .show();
+  }
+
   /**
    * Called by the adapter to set this ViewHolder's child views to display the list item
    * it must now represent.
diff --git a/Source/Android/app/src/main/java/org/dolphinemu/dolphinemu/features/settings/ui/viewholder/SwitchSettingViewHolder.java b/Source/Android/app/src/main/java/org/dolphinemu/dolphinemu/features/settings/ui/viewholder/SwitchSettingViewHolder.java
index ea7185b2ec..8e568baf32 100644
--- a/Source/Android/app/src/main/java/org/dolphinemu/dolphinemu/features/settings/ui/viewholder/SwitchSettingViewHolder.java
+++ b/Source/Android/app/src/main/java/org/dolphinemu/dolphinemu/features/settings/ui/viewholder/SwitchSettingViewHolder.java
@@ -7,13 +7,20 @@ import android.view.View;
 import androidx.annotation.Nullable;
 
 import org.dolphinemu.dolphinemu.databinding.ListItemSettingSwitchBinding;
+import org.dolphinemu.dolphinemu.features.settings.model.BooleanSetting;
 import org.dolphinemu.dolphinemu.features.settings.model.view.SwitchSetting;
 import org.dolphinemu.dolphinemu.features.settings.model.view.SettingsItem;
 import org.dolphinemu.dolphinemu.features.settings.ui.SettingsAdapter;
+import org.dolphinemu.dolphinemu.utils.DirectoryInitialization;
+
+import java.io.File;
+import java.util.ArrayList;
+import java.util.Arrays;
 
 public final class SwitchSettingViewHolder extends SettingViewHolder
 {
   private SwitchSetting mItem;
+  private boolean iplExists = false;
 
   private final ListItemSettingSwitchBinding mBinding;
 
@@ -32,11 +39,43 @@ public final class SwitchSettingViewHolder extends SettingViewHolder
     mBinding.textSettingDescription.setText(item.getDescription());
 
     mBinding.settingSwitch.setChecked(mItem.isChecked(getAdapter().getSettings()));
+    mBinding.settingSwitch.setEnabled(true);
 
-    mBinding.settingSwitch.setEnabled(mItem.isEditable());
+    // Check for IPL to make sure user can skip.
+    if (mItem.getSetting() == BooleanSetting.MAIN_SKIP_IPL)
+    {
+      ArrayList<String> iplDirs = new ArrayList<>(Arrays.asList("USA", "JAP", "EUR"));
+      for (String dir : iplDirs)
+      {
+        File iplFile = new File(DirectoryInitialization.getUserDirectory(),
+                File.separator + "GC" + File.separator + dir + File.separator + "IPL.bin");
+        if (iplFile.exists())
+        {
+          iplExists = true;
+          break;
+        }
+      }
+
+      if (mItem.isChecked(getAdapter().getSettings()))
+      {
+        mBinding.settingSwitch.setEnabled(iplExists);
+      }
+      else
+      {
+        mBinding.settingSwitch.setEnabled(true);
+      }
+    }
 
     mBinding.settingSwitch.setOnCheckedChangeListener((buttonView, isChecked) ->
     {
+      // If a user has skip IPL disabled previously and deleted their IPL file, we need to allow
+      // them to skip it or else their game will appear broken. However, once this is enabled, we
+      // need to disable the option again to prevent the same issue from occurring.
+      if (mItem.getSetting() == BooleanSetting.MAIN_SKIP_IPL && !iplExists && isChecked)
+      {
+        mBinding.settingSwitch.setEnabled(false);
+      }
+
       getAdapter().onBooleanClick(mItem, mBinding.settingSwitch.isChecked());
 
       setStyle(mBinding.textSettingName, mItem);
@@ -54,6 +93,15 @@ public final class SwitchSettingViewHolder extends SettingViewHolder
       return;
     }
 
+    if (mItem.getSetting() == BooleanSetting.MAIN_SKIP_IPL && !iplExists)
+    {
+      if (mItem.isChecked(getAdapter().getSettings()))
+      {
+        showIplNotAvailableError();
+        return;
+      }
+    }
+
     mBinding.settingSwitch.toggle();
   }
 
diff --git a/Source/Android/app/src/main/res/values/strings.xml b/Source/Android/app/src/main/res/values/strings.xml
index 163a78c3be..670bb3181e 100644
--- a/Source/Android/app/src/main/res/values/strings.xml
+++ b/Source/Android/app/src/main/res/values/strings.xml
@@ -642,6 +642,7 @@ It can efficiently compress both junk data and encrypted Wii data.
     <string name="path_not_changeable_scoped_storage">Due to the Scoped Storage policy in Android 11 and newer, you can\'t change this path.</string>
     <string name="load_settings">Loading Settings…</string>
     <string name="setting_not_runtime_editable">This setting can\'t be changed while a game is running.</string>
+    <string name="ipl_not_found">IPL not found</string>
     <string name="setting_clear_info">Long press a setting to clear it.</string>
     <string name="setting_clear_confirm">Do you want to restore this setting to its default value?</string>
     <string name="setting_cleared">Setting cleared</string>