diff --git a/CMake/FindCUBEB.cmake b/CMake/FindCUBEB.cmake
index c0a730c7ab..94ed431a9b 100644
--- a/CMake/FindCUBEB.cmake
+++ b/CMake/FindCUBEB.cmake
@@ -6,7 +6,7 @@ include(FindPackageHandleStandardArgs)
 find_package_handle_standard_args(CUBEB DEFAULT_MSG
 	CUBEB_INCLUDE_DIR CUBEB_LIBRARY)
 
-if(CUBEB_FOUND AND NOT TARGET CUBEB)
+if(CUBEB_FOUND AND NOT TARGET cubeb::cubeb)
   add_library(cubeb::cubeb UNKNOWN IMPORTED)
   set_target_properties(cubeb::cubeb PROPERTIES
     IMPORTED_LOCATION "${CUBEB_LIBRARY}"
diff --git a/CMake/FindLZO.cmake b/CMake/FindLZO.cmake
new file mode 100644
index 0000000000..2a146b37c8
--- /dev/null
+++ b/CMake/FindLZO.cmake
@@ -0,0 +1,15 @@
+find_path(LZO_INCLUDE_DIR lzo/lzo1x.h)
+find_library(LZO_LIBRARY lzo2)
+mark_as_advanced(LZO_INCLUDE_DIR LZO_LIBRARY)
+
+include(FindPackageHandleStandardArgs)
+find_package_handle_standard_args(LZO DEFAULT_MSG
+	LZO_INCLUDE_DIR LZO_LIBRARY)
+
+if(LZO_FOUND AND NOT TARGET LZO::LZO)
+  add_library(LZO::LZO UNKNOWN IMPORTED)
+  set_target_properties(LZO::LZO PROPERTIES
+    IMPORTED_LOCATION "${LZO_LIBRARY}"
+    INTERFACE_INCLUDE_DIRECTORIES "${LZO_INCLUDE_DIR}"
+  )
+endif()
diff --git a/CMake/FindLibUSB.cmake b/CMake/FindLibUSB.cmake
index dec0b98b07..c087edfcb8 100644
--- a/CMake/FindLibUSB.cmake
+++ b/CMake/FindLibUSB.cmake
@@ -40,4 +40,11 @@ elseif (NOT LIBUSB_FOUND)
 
     mark_as_advanced(LIBUSB_INCLUDE_DIR LIBUSB_LIBRARIES)
 endif ()
+if(LIBUSB_FOUND AND NOT TARGET LibUSB::LibUSB)
+    add_library(LibUSB::LibUSB UNKNOWN IMPORTED)
+    set_target_properties(LibUSB::LibUSB PROPERTIES
+        IMPORTED_LOCATION "${LIBUSB_LIBRARIES}"
+        INTERFACE_INCLUDE_DIRECTORIES "${LIBUSB_INCLUDE_DIR}"
+    )
+endif()
 
diff --git a/CMake/FindMBEDTLS.cmake b/CMake/FindMBEDTLS.cmake
index 6059dc9639..6512cc92f6 100644
--- a/CMake/FindMBEDTLS.cmake
+++ b/CMake/FindMBEDTLS.cmake
@@ -7,18 +7,53 @@ find_library(MBEDCRYPTO_LIBRARY mbedcrypto PATH_SUFFIXES mbedtls2)
 set(MBEDTLS_INCLUDE_DIRS ${MBEDTLS_INCLUDE_DIR})
 set(MBEDTLS_LIBRARIES ${MBEDTLS_LIBRARY} ${MBEDX509_LIBRARY} ${MBEDCRYPTO_LIBRARY})
 
-set(CMAKE_REQUIRED_INCLUDES ${MBEDTLS_INCLUDE_DIRS})
-check_cxx_source_compiles("
-	#include <mbedtls/version.h>
-	#if MBEDTLS_VERSION_NUMBER < 0x021C0000
-	#error \"Your mbed TLS version is too old.\"
-	#endif
-	int main() {}"
-	MBEDTLS_VERSION_OK)
-unset(CMAKE_REQUIRED_INCLUDES)
+if(NOT MBEDTLS_INCLUDE_DIR STREQUAL "MBEDTLS_INCLUDE_DIR-NOTFOUND")
+	if(EXISTS ${MBEDTLS_INCLUDE_DIR}/mbedtls/build_info.h)
+	    file(STRINGS ${MBEDTLS_INCLUDE_DIR}/mbedtls/build_info.h MBEDTLS_VERSION_STR REGEX "^#define[ \t]+MBEDTLS_VERSION_STRING[\t ].*")
+	else()
+	    file(STRINGS ${MBEDTLS_INCLUDE_DIR}/mbedtls/version.h MBEDTLS_VERSION_STR REGEX "^#define[ \t]+MBEDTLS_VERSION_STRING[\t ].*")
+	endif()
+	string(REGEX REPLACE "^#define[\t ]+MBEDTLS_VERSION_STRING[\t ]+\"([.0-9]+)\".*" "\\1" MBEDTLS_VERSION ${MBEDTLS_VERSION_STR})
+endif()
 
-include(FindPackageHandleStandardArgs)
-find_package_handle_standard_args(MBEDTLS DEFAULT_MSG
-	MBEDTLS_INCLUDE_DIR MBEDTLS_LIBRARY MBEDX509_LIBRARY MBEDCRYPTO_LIBRARY MBEDTLS_VERSION_OK)
+if(NOT MBEDTLS_INCLUDE_DIR STREQUAL "MBEDTLS_INCLUDE_DIR-NOTFOUND" AND MBEDTLS_VERSION VERSION_GREATER_EQUAL 3)
+	# Once CMake 3.19 is required, we can enable HANDLE_VERSION_RANGE and use that
+	if(MBEDTLS_FIND_REQUIRED)
+		set(type FATAL_ERROR)
+	else()
+		set(type STATUS)
+	endif()
+	if(MBEDTLS_FIND_REQUIRED OR NOT MBEDTLS_FIND_QUIETLY)
+		message(${type} "Could NOT find MBEDTLS: Found unsuitable version \"${MBEDTLS_VERSION}\", but a 2.x version is required (found ${MBEDTLS_INCLUDE_DIR})")
+	endif()
+	set(MBEDTLS_FOUND FALSE)
+else()
+	include(FindPackageHandleStandardArgs)
+	find_package_handle_standard_args(MBEDTLS
+		REQUIRED_VARS MBEDTLS_INCLUDE_DIR MBEDTLS_LIBRARY MBEDX509_LIBRARY MBEDCRYPTO_LIBRARY
+		VERSION_VAR MBEDTLS_VERSION)
+endif()
 
 mark_as_advanced(MBEDTLS_INCLUDE_DIR MBEDTLS_LIBRARY MBEDX509_LIBRARY MBEDCRYPTO_LIBRARY)
+
+if(MBEDTLS_FOUND)
+	add_library(MbedTLS::mbedcrypto UNKNOWN IMPORTED)
+	set_target_properties(MbedTLS::mbedcrypto PROPERTIES
+	    IMPORTED_LOCATION "${MBEDCRYPTO_LIBRARY}"
+	    INTERFACE_INCLUDE_DIRECTORIES "${MBEDTLS_INCLUDE_DIR}"
+	)
+
+	add_library(MbedTLS::mbedx509 UNKNOWN IMPORTED)
+	set_target_properties(MbedTLS::mbedx509 PROPERTIES
+	    IMPORTED_LOCATION "${MBEDX509_LIBRARY}"
+	    INTERFACE_INCLUDE_DIRECTORIES "${MBEDTLS_INCLUDE_DIR}"
+	    INTERFACE_LINK_LIBRARIES MbedTLS::mbedcrypto
+	)
+
+	add_library(MbedTLS::mbedtls UNKNOWN IMPORTED)
+	set_target_properties(MbedTLS::mbedtls PROPERTIES
+	    IMPORTED_LOCATION "${MBEDTLS_LIBRARY}"
+	    INTERFACE_INCLUDE_DIRECTORIES "${MBEDTLS_INCLUDE_DIR}"
+	    INTERFACE_LINK_LIBRARIES MbedTLS::mbedx509
+	)
+endif()
diff --git a/CMake/FindMINIUPNPC.cmake b/CMake/FindMINIUPNPC.cmake
index f9a14e2a89..edfc5b2b9d 100644
--- a/CMake/FindMINIUPNPC.cmake
+++ b/CMake/FindMINIUPNPC.cmake
@@ -5,14 +5,17 @@ find_path(MINIUPNPC_INCLUDE_DIR miniupnpc.h PATH_SUFFIXES miniupnpc)
 find_library(MINIUPNPC_LIBRARY miniupnpc)
 
 if(MINIUPNPC_INCLUDE_DIR)
-	file(STRINGS "${MINIUPNPC_INCLUDE_DIR}/miniupnpc.h" MINIUPNPC_API_VERSION_STR REGEX "^#define[\t ]+MINIUPNPC_API_VERSION[\t ]+[0-9]+")
-	if(MINIUPNPC_API_VERSION_STR)
-		string(REGEX REPLACE "^#define[\t ]+MINIUPNPC_API_VERSION[\t ]+([0-9]+)" "\\1" MINIUPNPC_API_VERSION ${MINIUPNPC_API_VERSION_STR})
+	file(STRINGS "${MINIUPNPC_INCLUDE_DIR}/miniupnpc.h" MINIUPNPC_VERSION_STR REGEX "^#define[\t ]+MINIUPNPC_VERSION[\t ]+.*")
+	if(MINIUPNPC_VERSION_STR)
+		string(REGEX REPLACE "^#define[\t ]+MINIUPNPC_VERSION[\t ]+\"([.0-9]+)\"" "\\1" MINIUPNPC_VERSION ${MINIUPNPC_VERSION_STR})
 	endif()
 endif()
 
 include(FindPackageHandleStandardArgs)
-find_package_handle_standard_args(MINIUPNPC DEFAULT_MSG MINIUPNPC_INCLUDE_DIR MINIUPNPC_LIBRARY MINIUPNPC_API_VERSION)
+find_package_handle_standard_args(MINIUPNPC
+	REQUIRED_VARS MINIUPNPC_INCLUDE_DIR MINIUPNPC_LIBRARY
+	VERSION_VAR MINIUPNPC_VERSION
+)
 
 set(MINIUPNPC_LIBRARIES ${MINIUPNPC_LIBRARY})
 set(MINIUPNPC_INCLUDE_DIRS ${MINIUPNPC_INCLUDE_DIR})
diff --git a/CMake/FindSFML.cmake b/CMake/FindSFML.cmake
index d6acdfb6d6..b5b26a5f00 100644
--- a/CMake/FindSFML.cmake
+++ b/CMake/FindSFML.cmake
@@ -206,4 +206,20 @@ endif()
 # handle success
 if(SFML_FOUND)
     message(STATUS "Found SFML ${SFML_VERSION_MAJOR}.${SFML_VERSION_MINOR} in ${SFML_INCLUDE_DIR}")
+    foreach(FIND_SFML_COMPONENT ${SFML_FIND_COMPONENTS})
+        string(TOLOWER ${FIND_SFML_COMPONENT} FIND_SFML_COMPONENT_LOWER)
+        string(TOUPPER ${FIND_SFML_COMPONENT} FIND_SFML_COMPONENT_UPPER)
+        if(NOT TARGET sfml-${FIND_SFML_COMPONENT_LOWER})
+            add_library(sfml-${FIND_SFML_COMPONENT_LOWER} UNKNOWN IMPORTED)
+            set_target_properties(sfml-${FIND_SFML_COMPONENT_LOWER} PROPERTIES
+                IMPORTED_LOCATION "${SFML_${FIND_SFML_COMPONENT_UPPER}_LIBRARY}"
+                INTERFACE_INCLUDE_DIRECTORIES "${SFML_INCLUDE_DIR}"
+            )
+            if(NOT ${FIND_SFML_COMPONENT_LOWER} STREQUAL system)
+                set_target_properties(sfml-${FIND_SFML_COMPONENT_LOWER} PROPERTIES
+                    INTERFACE_LINK_LIBRARIES sfml-system
+                )
+            endif()
+        endif()
+    endforeach()
 endif()
diff --git a/CMakeLists.txt b/CMakeLists.txt
index 4d72091752..f973dc7ae2 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -85,7 +85,6 @@ if(NOT ANDROID)
   option(ENABLE_CLI_TOOL "Enable dolphin-tool, a CLI-based utility for functions such as managing disc images" ON)
 endif()
 
-option(USE_SHARED_ENET "Use shared libenet if found rather than Dolphin's soon-to-compatibly-diverge version" OFF)
 option(USE_UPNP "Enables UPnP port mapping support" ON)
 option(ENABLE_NOGUI "Enable NoGUI frontend" ON)
 option(ENABLE_QT "Enable Qt (Default)" ON)
@@ -645,26 +644,8 @@ if(ENABLE_SDL)
     message(STATUS "Using system SDL2")
   else()
     message(STATUS "Using static SDL2 from Externals")
-    option(SDL2_DISABLE_SDL2MAIN "" ON)
-    option(SDL2_DISABLE_INSTALL "" ON)
-    option(SDL2_DISABLE_UNINSTALL "" ON)
-    set(SDL_SHARED OFF)
-    set(SDL_SHARED_ENABLED_BY_DEFAULT OFF)
-    set(SDL_STATIC ON)
-    set(SDL_STATIC_ENABLED_BY_DEFAULT ON)
-    set(SDL_TEST OFF)
-    set(SDL_TEST_ENABLED_BY_DEFAULT OFF)
-    set(OPT_DEF_LIBC ON)
-    add_subdirectory(Externals/SDL/SDL)
-    if (TARGET SDL2)
-      dolphin_disable_warnings_msvc(SDL2)
-    endif()
-    if (TARGET SDL2-static)
-      dolphin_disable_warnings_msvc(SDL2-static)
-    endif()
-    set(SDL2_FOUND TRUE)
+    add_subdirectory(Externals/SDL)
   endif()
-  add_definitions(-DHAVE_SDL2=1)
 endif()
 
 if(ENABLE_ANALYTICS)
@@ -747,31 +728,13 @@ if(NOT pugixml_FOUND)
   add_subdirectory(Externals/pugixml)
 endif()
 
-if(USE_SHARED_ENET)
-  check_lib(ENET libenet enet enet/enet.h QUIET)
-  include(CheckSymbolExists)
-  if (ENET_FOUND)
-    set(CMAKE_REQUIRED_INCLUDES ${ENET_INCLUDE_DIRS})
-    # hack: LDFLAGS already contains -lenet but all flags but the first are
-    # dropped; ugh, cmake
-    set(CMAKE_REQUIRED_FLAGS ${ENET_LDFLAGS})
-    set(CMAKE_REQUIRED_LIBRARIES ${ENET_LIBRARIES})
-    check_symbol_exists(enet_socket_get_address enet/enet.h ENET_HAVE_SGA)
-    set(CMAKE_REQUIRED_INCLUDES)
-    set(CMAKE_REQUIRED_FLAGS)
-    set(CMAKE_REQUIRED_LIBRARIES)
-    if (NOT ENET_HAVE_SGA)
-      # enet is too old
-     set(ENET_FOUND FALSE)
-    endif()
-  endif()
-endif()
-if (ENET_FOUND)
+pkg_check_modules(ENET libenet>=1.3.8 IMPORTED_TARGET)
+if(ENET_FOUND)
   message(STATUS "Using shared enet")
+  dolphin_alias_library(enet::enet PkgConfig::ENET)
 else()
   check_vendoring_approved(enet)
   message(STATUS "Using static enet from Externals")
-  include_directories(Externals/enet/include)
   add_subdirectory(Externals/enet)
 endif()
 
@@ -813,37 +776,32 @@ endif()
 
 add_subdirectory(Externals/zlib-ng)
 
-pkg_check_modules(MINIZIP minizip>=3.0.0)
+pkg_check_modules(MINIZIP minizip>=3.0.0 IMPORTED_TARGET)
 if(MINIZIP_FOUND)
   message(STATUS "Using shared minizip")
-  include_directories(${MINIZIP_INCLUDE_DIRS})
+  dolphin_alias_library(minizip::minizip PkgConfig::MINIZIP)
 else()
   check_vendoring_approved(minizip)
   message(STATUS "Shared minizip not found, falling back to the static library")
   add_subdirectory(Externals/minizip)
-  include_directories(External/minizip)
 endif()
 
-if(NOT APPLE)
-  check_lib(LZO "(no .pc for lzo2)" lzo2 lzo/lzo1x.h QUIET)
-endif()
+find_package(LZO)
 if(LZO_FOUND)
   message(STATUS "Using shared lzo")
 else()
   check_vendoring_approved(lzo)
   message(STATUS "Using static lzo from Externals")
-  add_subdirectory(Externals/LZO)
-  set(LZO lzo2)
+  add_subdirectory(Externals/LZO EXCLUDE_FROM_ALL)
 endif()
 
 pkg_check_modules(pc_spng IMPORTED_TARGET spng)
 if (pc_spng_FOUND AND TARGET PkgConfig::pc_spng)
   message(STATUS "Using the system libspng")
-  set(spng_target PkgConfig::pc_spng)
+  dolphin_alias_library(spng::spng PkgConfig::pc_spng)
 else()
   message(STATUS "Using static libspng from Externals")
   add_subdirectory(Externals/libspng)
-  set(spng_target spng)
 endif()
 
 # Using static FreeSurround from Externals
@@ -873,40 +831,28 @@ endif()
 
 if(NOT ANDROID)
   add_definitions(-D__LIBUSB__)
-  if(NOT APPLE)
-    find_package(LibUSB)
-  endif()
-  if(LIBUSB_FOUND AND NOT APPLE)
+  find_package(LibUSB)
+  if(LIBUSB_FOUND)
     message(STATUS "Using shared LibUSB")
-    include_directories(${LIBUSB_INCLUDE_DIR})
   else()
     check_vendoring_approved(libusb)
     message(STATUS "Using static LibUSB from Externals")
-    add_subdirectory(Externals/libusb)
-    set(LIBUSB_LIBRARIES usb)
+    add_subdirectory(Externals/libusb EXCLUDE_FROM_ALL)
   endif()
-  set(LIBUSB_FOUND true)
 endif()
 
-set(SFML_REQD_VERSION 2.1)
-if(NOT APPLE)
-  find_package(SFML ${SFML_REQD_VERSION} COMPONENTS network system)
-endif()
+find_package(SFML 2.1 COMPONENTS network system)
 if(SFML_FOUND)
   message(STATUS "Using shared SFML")
 else()
   check_vendoring_approved(sfml)
-  message(STATUS "Using static SFML ${SFML_REQD_VERSION} from Externals")
-  add_definitions(-DSFML_STATIC)
+  message(STATUS "Using static SFML from Externals")
   add_subdirectory(Externals/SFML)
-  include_directories(BEFORE Externals/SFML/include)
 endif()
 
 if(USE_UPNP)
-  if(NOT APPLE)
-    find_package(MINIUPNPC)
-  endif()
-  if(MINIUPNPC_FOUND AND MINIUPNPC_API_VERSION GREATER 8)
+  find_package(MINIUPNPC 1.6)
+  if(MINIUPNPC_FOUND)
     message(STATUS "Using shared miniupnpc")
   else()
     check_vendoring_approved(miniupnpc)
@@ -916,30 +862,22 @@ if(USE_UPNP)
   add_definitions(-DUSE_UPNP)
 endif()
 
-if(NOT APPLE)
-  find_package(MBEDTLS)
-endif()
+find_package(MBEDTLS 2.28)
 if(MBEDTLS_FOUND)
   message(STATUS "Using shared mbed TLS")
-  include_directories(${MBEDTLS_INCLUDE_DIRS})
 else()
   check_vendoring_approved(mbedtls)
   message(STATUS "Using static mbed TLS from Externals")
-  set(MBEDTLS_LIBRARIES mbedtls mbedcrypto mbedx509)
   add_subdirectory(Externals/mbedtls/ EXCLUDE_FROM_ALL)
-  include_directories(Externals/mbedtls/include)
 endif()
 
 find_package(CURL)
 if(CURL_FOUND)
   message(STATUS "Using shared libcurl")
-  include_directories(${CURL_INCLUDE_DIRS})
 else()
   check_vendoring_approved(curl)
   message(STATUS "Using static libcurl from Externals")
-  add_subdirectory(Externals/curl)
-  set(CURL_LIBRARIES curl)
-  include_directories(BEFORE Externals/curl/include)
+  add_subdirectory(Externals/curl EXCLUDE_FROM_ALL)
 endif()
 
 if(NOT ANDROID)
@@ -951,7 +889,7 @@ if(TARGET Iconv::Iconv)
 else()
   check_vendoring_approved(iconv)
   message(STATUS "Using static iconv from Externals")
-  add_subdirectory(Externals/libiconv-1.14)
+  add_subdirectory(Externals/libiconv-1.14 EXCLUDE_FROM_ALL)
 endif()
 
 if(NOT ANDROID)
diff --git a/Externals/LZO/CMakeLists.txt b/Externals/LZO/CMakeLists.txt
index 3bb91ee5c5..44b59bd496 100644
--- a/Externals/LZO/CMakeLists.txt
+++ b/Externals/LZO/CMakeLists.txt
@@ -7,3 +7,4 @@ target_include_directories(lzo2
 PUBLIC
   ${CMAKE_CURRENT_SOURCE_DIR}
 )
+add_library(LZO::LZO ALIAS lzo2)
diff --git a/Externals/SDL/CMakeLists.txt b/Externals/SDL/CMakeLists.txt
new file mode 100644
index 0000000000..15d3ffe4ce
--- /dev/null
+++ b/Externals/SDL/CMakeLists.txt
@@ -0,0 +1,17 @@
+option(SDL2_DISABLE_SDL2MAIN "" ON)
+option(SDL2_DISABLE_INSTALL "" ON)
+option(SDL2_DISABLE_UNINSTALL "" ON)
+set(SDL_SHARED OFF)
+set(SDL_SHARED_ENABLED_BY_DEFAULT OFF)
+set(SDL_STATIC ON)
+set(SDL_STATIC_ENABLED_BY_DEFAULT ON)
+set(SDL_TEST OFF)
+set(SDL_TEST_ENABLED_BY_DEFAULT OFF)
+set(OPT_DEF_LIBC ON)
+add_subdirectory(SDL)
+if (TARGET SDL2)
+  dolphin_disable_warnings_msvc(SDL2)
+endif()
+if (TARGET SDL2-static)
+  dolphin_disable_warnings_msvc(SDL2-static)
+endif()
diff --git a/Externals/SFML/CMakeLists.txt b/Externals/SFML/CMakeLists.txt
index aac2192cad..1b7060ef95 100644
--- a/Externals/SFML/CMakeLists.txt
+++ b/Externals/SFML/CMakeLists.txt
@@ -1,5 +1,3 @@
-include_directories(BEFORE include src)
-
 set(SRC_NETWORK
 	src/SFML/Network/Http.cpp
 	src/SFML/Network/IPAddress.cpp
@@ -23,7 +21,11 @@ set(SRC_SYSTEM
 	src/SFML/System/Time.cpp
 )
 
-add_library(sfml-network ${SRC_NETWORK})
-add_library(sfml-system ${SRC_SYSTEM})
+add_library(sfml-network STATIC ${SRC_NETWORK})
+add_library(sfml-system STATIC ${SRC_SYSTEM})
+target_compile_definitions(sfml-system PUBLIC SFML_STATIC)
+target_include_directories(sfml-system PUBLIC include PRIVATE src)
+target_include_directories(sfml-network PUBLIC include PRIVATE src)
+target_link_libraries(sfml-network PUBLIC sfml-system)
 dolphin_disable_warnings_msvc(sfml-network)
 dolphin_disable_warnings_msvc(sfml-system)
diff --git a/Externals/cubeb/CMakeLists.txt b/Externals/cubeb/CMakeLists.txt
index a9f904a093..07f4493dd9 100644
--- a/Externals/cubeb/CMakeLists.txt
+++ b/Externals/cubeb/CMakeLists.txt
@@ -352,3 +352,4 @@ if(USE_AUDIOUNIT AND USE_AUDIOUNIT_RUST)
     debug "${PROJECT_SOURCE_DIR}/cubeb/src/cubeb-coreaudio-rs/target/debug/libcubeb_coreaudio.a"
     optimized "${PROJECT_SOURCE_DIR}/cubeb/src/cubeb-coreaudio-rs/target/release/libcubeb_coreaudio.a")
 endif()
+add_library(cubeb::cubeb ALIAS cubeb)
diff --git a/Externals/curl/lib/CMakeLists.txt b/Externals/curl/lib/CMakeLists.txt
index dff7a63171..3679575463 100644
--- a/Externals/curl/lib/CMakeLists.txt
+++ b/Externals/curl/lib/CMakeLists.txt
@@ -4,8 +4,6 @@ else()
     add_definitions(-DHAVE_CONFIG_H)
 endif()
 
-include_directories(.)
-
 file(GLOB SRCS *.c vauth/*.c vtls/*.c)
 add_library(
   curl
@@ -14,5 +12,7 @@ add_library(
   )
 dolphin_disable_warnings_msvc(curl)
 
-target_link_libraries(curl ${MBEDTLS_LIBRARIES} zlibstatic)
+target_include_directories(curl PRIVATE . INTERFACE ../include)
+target_link_libraries(curl MbedTLS::mbedtls zlibstatic)
 target_compile_definitions(curl PUBLIC CURL_STATICLIB PRIVATE CURL_DISABLE_LDAP)
+add_library(CURL::libcurl ALIAS curl)
diff --git a/Externals/enet/CMakeLists.txt b/Externals/enet/CMakeLists.txt
index 7088bf3291..f6244a7f4e 100644
--- a/Externals/enet/CMakeLists.txt
+++ b/Externals/enet/CMakeLists.txt
@@ -59,8 +59,6 @@ if(HAS_SOCKLEN_T)
     add_definitions(-DHAS_SOCKLEN_T=1)
 endif()
 
-include_directories(${PROJECT_SOURCE_DIR}/include)
-
 set(INCLUDE_FILES_PREFIX include/enet)
 set(INCLUDE_FILES
     ${INCLUDE_FILES_PREFIX}/callbacks.h
@@ -92,8 +90,10 @@ add_library(enet STATIC
     ${INCLUDE_FILES}
     ${SOURCE_FILES}
 )
+target_include_directories(enet PUBLIC include)
 
 dolphin_disable_warnings_msvc(enet)
+add_library(enet::enet ALIAS enet)
 
 if (MINGW)
     target_link_libraries(enet winmm ws2_32)
diff --git a/Externals/libspng/CMakeLists.txt b/Externals/libspng/CMakeLists.txt
index 7576534a67..315997a45a 100644
--- a/Externals/libspng/CMakeLists.txt
+++ b/Externals/libspng/CMakeLists.txt
@@ -2,8 +2,9 @@ cmake_minimum_required(VERSION 3.0)
 
 project(spng C)
 
-add_library(spng STATIC ${CMAKE_CURRENT_LIST_DIR}/libspng/spng/spng.c)
+add_library(spng STATIC libspng/spng/spng.c)
 target_compile_definitions(spng PUBLIC SPNG_STATIC)
 target_link_libraries(spng PUBLIC ZLIB::ZLIB)
-target_include_directories(spng PUBLIC ${CMAKE_CURRENT_LIST_DIR}/libspng/spng/)
+target_include_directories(spng PUBLIC libspng/spng)
 dolphin_disable_warnings_msvc(spng)
+add_library(spng::spng ALIAS spng)
diff --git a/Externals/libusb/CMakeLists.txt b/Externals/libusb/CMakeLists.txt
index f3bed0d1f0..47ff1d8e0d 100644
--- a/Externals/libusb/CMakeLists.txt
+++ b/Externals/libusb/CMakeLists.txt
@@ -125,3 +125,4 @@ check_include_files(sys/timerfd.h HAVE_TIMERFD)
 check_include_files(unistd.h HAVE_UNISTD_H)
 
 configure_file(config.h.in config.h)
+add_library(LibUSB::LibUSB ALIAS usb)
diff --git a/Externals/mbedtls/library/CMakeLists.txt b/Externals/mbedtls/library/CMakeLists.txt
index ba0b337ea1..fc2786c7f2 100644
--- a/Externals/mbedtls/library/CMakeLists.txt
+++ b/Externals/mbedtls/library/CMakeLists.txt
@@ -222,6 +222,7 @@ if(USE_SHARED_MBEDTLS_LIBRARY)
 endif(USE_SHARED_MBEDTLS_LIBRARY)
 
 foreach(target IN LISTS target_libraries)
+    add_library(MbedTLS::${target} ALIAS ${target})  # add_subdirectory support
     # Include public header files from /include and other directories
     # declared by /3rdparty/**/CMakeLists.txt. Include private header files
     # from /library and others declared by /3rdparty/**/CMakeLists.txt.
diff --git a/Externals/minizip/CMakeLists.txt b/Externals/minizip/CMakeLists.txt
index c3d7c5512e..09aba92e57 100644
--- a/Externals/minizip/CMakeLists.txt
+++ b/Externals/minizip/CMakeLists.txt
@@ -67,4 +67,4 @@ endif()
 
 target_link_libraries(minizip PUBLIC ZLIB::ZLIB)
 
-add_library(minizip-ng ALIAS minizip)
+add_library(minizip::minizip ALIAS minizip)
diff --git a/Source/Core/AudioCommon/CMakeLists.txt b/Source/Core/AudioCommon/CMakeLists.txt
index 18cc67470b..26dc443d90 100644
--- a/Source/Core/AudioCommon/CMakeLists.txt
+++ b/Source/Core/AudioCommon/CMakeLists.txt
@@ -83,7 +83,7 @@ PUBLIC
   common
 
 PRIVATE
-  cubeb
+  cubeb::cubeb
   SoundTouch
   FreeSurround)
 
diff --git a/Source/Core/Common/CMakeLists.txt b/Source/Core/Common/CMakeLists.txt
index d3a756e6e2..6233f847a0 100644
--- a/Source/Core/Common/CMakeLists.txt
+++ b/Source/Core/Common/CMakeLists.txt
@@ -144,16 +144,17 @@ endif()
 target_link_libraries(common
 PUBLIC
   ${CMAKE_THREAD_LIBS_INIT}
-  enet
+  enet::enet
   fmt::fmt
-  ${MBEDTLS_LIBRARIES}
-  minizip-ng
+  MbedTLS::mbedtls
+  minizip::minizip
+  sfml-network
 
 PRIVATE
-  ${CURL_LIBRARIES}
+  CURL::libcurl
   FatFs
   Iconv::Iconv
-  ${spng_target}
+  spng::spng
   ${VTUNE_LIBRARIES}
 )
 
diff --git a/Source/Core/Core/CMakeLists.txt b/Source/Core/Core/CMakeLists.txt
index f6fb444118..b3eb8dac64 100644
--- a/Source/Core/Core/CMakeLists.txt
+++ b/Source/Core/Core/CMakeLists.txt
@@ -603,24 +603,23 @@ target_link_libraries(core
 PUBLIC
   audiocommon
   common
-  cubeb
   discio
-  enet
+  enet::enet
   expr
   inputcommon
-  ${MBEDTLS_LIBRARIES}
+  MbedTLS::mbedtls
   pugixml
   RangeSet::RangeSet
   sfml-network
-  sfml-system
   videonull
   videoogl
   videosoftware
 
 PRIVATE
+  cubeb::cubeb
   FatFs
   fmt::fmt
-  ${LZO}
+  LZO::LZO
   ZLIB::ZLIB
 )
 
@@ -644,9 +643,8 @@ elseif (ANDROID)
   )
 endif()
 
-if(LIBUSB_FOUND)
-  # Using shared LibUSB
-  target_link_libraries(core PUBLIC ${LIBUSB_LIBRARIES})
+if(TARGET LibUSB::LibUSB)
+  target_link_libraries(core PUBLIC LibUSB::LibUSB)
   target_sources(core PRIVATE
     IOS/USB/LibusbDevice.cpp
     IOS/USB/LibusbDevice.h
diff --git a/Source/Core/DiscIO/CMakeLists.txt b/Source/Core/DiscIO/CMakeLists.txt
index 44d4af95b8..11fb5cf52a 100644
--- a/Source/Core/DiscIO/CMakeLists.txt
+++ b/Source/Core/DiscIO/CMakeLists.txt
@@ -75,7 +75,7 @@ PUBLIC
 
 PRIVATE
   fmt::fmt
-  minizip-ng
+  minizip::minizip
   pugixml
   ZLIB::ZLIB
 )
diff --git a/Source/Core/InputCommon/CMakeLists.txt b/Source/Core/InputCommon/CMakeLists.txt
index 0343717a34..ed19e12b74 100644
--- a/Source/Core/InputCommon/CMakeLists.txt
+++ b/Source/Core/InputCommon/CMakeLists.txt
@@ -81,7 +81,8 @@ PUBLIC
 
 PRIVATE
   fmt::fmt
-  ${spng_target}
+  sfml-network
+  spng::spng
 )
 
 if(WIN32)
@@ -146,7 +147,7 @@ elseif(ANDROID)
 endif()
 
 if(NOT ANDROID)
-  target_link_libraries(inputcommon PUBLIC ${LIBUSB_LIBRARIES})
+  target_link_libraries(inputcommon PUBLIC LibUSB::LibUSB)
 endif()
 
 if(LIBEVDEV_FOUND AND LIBUDEV_FOUND)
@@ -174,12 +175,13 @@ if(UNIX)
   )
 endif()
 
-if(SDL2_FOUND)
+if(ENABLE_SDL)
   target_sources(inputcommon PRIVATE
     ControllerInterface/SDL/SDL.cpp
     ControllerInterface/SDL/SDL.h
   )
   target_link_libraries(inputcommon PRIVATE SDL2::SDL2)
+  target_compile_definitions(inputcommon PUBLIC HAVE_SDL2=1)
 endif()
 
 if(MSVC)
diff --git a/Source/Core/UICommon/CMakeLists.txt b/Source/Core/UICommon/CMakeLists.txt
index 947aeae346..7505f9c9f5 100644
--- a/Source/Core/UICommon/CMakeLists.txt
+++ b/Source/Core/UICommon/CMakeLists.txt
@@ -29,7 +29,7 @@ target_link_libraries(uicommon
 PUBLIC
   common
   cpp-optparse
-  minizip-ng
+  minizip::minizip
   pugixml
 
 PRIVATE
@@ -48,8 +48,8 @@ if(ENABLE_X11 AND X11_FOUND)
   target_link_libraries(uicommon PUBLIC ${XRANDR_LIBRARIES})
 endif()
 
-if(LIBUSB_FOUND)
-  target_link_libraries(uicommon PRIVATE ${LIBUSB_LIBRARIES})
+if(TARGET LibUSB::LibUSB)
+  target_link_libraries(uicommon PRIVATE LibUSB::LibUSB)
 endif()
 
 if(ENABLE_LLVM)
diff --git a/Source/Core/UpdaterCommon/CMakeLists.txt b/Source/Core/UpdaterCommon/CMakeLists.txt
index c026cd577d..9bc1f9ab45 100644
--- a/Source/Core/UpdaterCommon/CMakeLists.txt
+++ b/Source/Core/UpdaterCommon/CMakeLists.txt
@@ -6,7 +6,7 @@ add_library(updatercommon
 
 target_link_libraries(updatercommon PRIVATE
   uicommon
-  mbedtls
+  MbedTLS::mbedtls
   ZLIB::ZLIB
   ed25519
   cpp-optparse
diff --git a/Source/Core/VideoCommon/CMakeLists.txt b/Source/Core/VideoCommon/CMakeLists.txt
index ed8642fb1e..acb011cbb1 100644
--- a/Source/Core/VideoCommon/CMakeLists.txt
+++ b/Source/Core/VideoCommon/CMakeLists.txt
@@ -195,7 +195,7 @@ PUBLIC
   core
 PRIVATE
   fmt::fmt
-  ${spng_target}
+  spng::spng
   xxhash
   imgui
   implot