diff --git a/CMakeLists.txt b/CMakeLists.txt
index 29e41047a1..13688ae5fe 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -168,8 +168,8 @@ if(APPLE)
 	set(ENV{PATH} /usr/bin:/bin:/usr/sbin:/sbin)
 
 	# Some of our code contains Objective C constructs.
-	set(CMAKE_C_FLAGS "${CMAKE_C_FLAGS} -x objective-c")
-	set(CMAKE_CXX_FLAGS "${CMAKE_CXX_FLAGS} -x objective-c++")
+	set(CMAKE_C_FLAGS "${CMAKE_C_FLAGS} -x objective-c -stdlib=libc++")
+	set(CMAKE_CXX_FLAGS "${CMAKE_CXX_FLAGS} -x objective-c++ -stdlib=libc++")
 	# Avoid mistaking an object file for a source file on the link command line.
 	set(CMAKE_EXE_LINKER_FLAGS "${CMAKE_EXE_LINKER_FLAGS} -x none")
 
@@ -180,10 +180,10 @@ if(APPLE)
 	# This is inserted into the Info.plist as well.
 	# Note that the SDK determines the maximum version of which optional
 	# features can be used, not the minimum required version to run.
-	set(OSX_MIN_VERSION "10.5.4")
+	set(OSX_MIN_VERSION "10.7")
 	set(TARGET_FLAGS "${TARGET_FLAGS} -mmacosx-version-min=${OSX_MIN_VERSION}")
-	set(SYSROOT_LEGACY_PATH "/Developer/SDKs/MacOSX10.6.sdk")
-	set(SYSROOT_PATH "/Applications/Xcode.app/Contents/Developer/Platforms/MacOSX.platform/Developer/SDKs/MacOSX10.6.sdk")
+	set(SYSROOT_LEGACY_PATH "/Developer/SDKs/MacOSX10.7.sdk")
+	set(SYSROOT_PATH "/Applications/Xcode.app/Contents/Developer/Platforms/MacOSX.platform/Developer/SDKs/MacOSX10.7.sdk")
 	if(EXISTS "${SYSROOT_PATH}/")
         set(TARGET_SYSROOT ${SYSROOT_PATH})
 	elseif(EXISTS "${SYSROOT_LEGACY_PATH}/")
@@ -197,8 +197,8 @@ if(APPLE)
 	# This avoids a warning when linking with QuickTime.
 	set(CMAKE_EXE_LINKER_FLAGS "${CMAKE_EXE_LINKER_FLAGS} -Wl,-no_arch_warnings")
 	# Specify target CPUs.
-	set(TARGET_FLAGS "${TARGET_FLAGS} -Xarch_x86_64 -mssse3")
-	set(TARGET_FLAGS "${TARGET_FLAGS} -Xarch_x86_64 -march=core2")
+	set(TARGET_FLAGS "${TARGET_FLAGS} -mssse3")
+	set(TARGET_FLAGS "${TARGET_FLAGS} -march=core2")
 	# Target flags apply to both C and C++ compilation.
 	# CMake passes these to the compiler on the link command line as well.
 	set(CMAKE_C_FLAGS "${CMAKE_C_FLAGS} ${TARGET_FLAGS}")
@@ -247,7 +247,7 @@ if(CMAKE_BUILD_TYPE STREQUAL Debug)
 	set(wxWidgets_USE_DEBUG ON CACHE BOOL "Use wxWidgets Debugging")
 endif(CMAKE_BUILD_TYPE STREQUAL Debug)
 
-if(CMAKE_BUILD_TYPE STREQUAL Release)
+if(CMAKE_BUILD_TYPE STREQUAL Release AND NOT APPLE)
 	add_definitions(-fomit-frame-pointer)
 endif(CMAKE_BUILD_TYPE STREQUAL Release)
 
diff --git a/Externals/wxWidgets3/build_wx.sh b/Externals/wxWidgets3/build_wx.sh
index 2173572bfa..82670d6e9f 100755
--- a/Externals/wxWidgets3/build_wx.sh
+++ b/Externals/wxWidgets3/build_wx.sh
@@ -5,7 +5,9 @@ cd wxWidgets
 
 case $OSTYPE in
 darwin*)
+export CC=clang CXX=clang++ CFLAGS="-stdlib=libc++" CXXFLAGS="-stdlib=libc++" CPPFLAGS="-stdlib=libc++"
 BACKEND="osx_cocoa"
+ADD_OPTS=--with-macosx-version-min=10.7 --enable-stl
 ;;
 linux*)
 BACKEND="gtk"
@@ -15,5 +17,5 @@ esac
 mkdir build-local
 cd build-local
 
-../configure --with-$BACKEND --disable-shared --enable-unicode --disable-compat28 --disable-exceptions --disable-fswatcher --without-regex --without-expat --disable-xml --disable-ribbon --disable-propgrid --disable-stc --disable-html --disable-richtext --without-libjpeg --without-libtiff --disable-webview --disable-markup
+../configure --with-$BACKEND --disable-shared --enable-unicode --disable-compat28 --disable-exceptions --disable-fswatcher --without-regex --without-expat --disable-xml --disable-ribbon --disable-propgrid --disable-stc --disable-html --disable-richtext --without-libjpeg --without-libtiff --disable-webview --disable-markup $ADD_OPTS
 make
diff --git a/Externals/wxWidgets3/wx/wxcocoa.h b/Externals/wxWidgets3/wx/wxcocoa.h
index 841d17e949..33a19cda5b 100644
--- a/Externals/wxWidgets3/wx/wxcocoa.h
+++ b/Externals/wxWidgets3/wx/wxcocoa.h
@@ -16,7 +16,7 @@
 #endif /* __cplusplus */
 
 /* fill in with the string wxGetOsDescription() will return */
-#define WXWIN_OS_DESCRIPTION "Darwin 11.3.0 i386"
+#define WXWIN_OS_DESCRIPTION "Darwin 11.4.2 x86_64"
 
 /* the installation location prefix from configure */
 #define wxINSTALL_PREFIX "/usr/local"
@@ -205,7 +205,7 @@
 
 
 
-#define wxUSE_STL 0
+#define wxUSE_STL 1
 
 #if defined(__DMC__) || defined(__WATCOMC__) \
         || (defined(_MSC_VER) && _MSC_VER < 1200)
@@ -214,7 +214,7 @@
     #define wxUSE_STD_DEFAULT  0
 #endif
 
-#define wxUSE_STD_CONTAINERS 0
+#define wxUSE_STD_CONTAINERS 1
 
 #define wxUSE_STD_IOSTREAM 1
 
@@ -715,7 +715,7 @@
 /*
  * Define if your compiler has compliant std::string::compare
  */
-/* #undef HAVE_STD_STRING_COMPARE */
+#define HAVE_STD_STRING_COMPARE 1
 /*
  * Define if your compiler has <hash_map>
  */
@@ -736,12 +736,12 @@
 /*
  * Define if your compiler has std::unordered_map
  */
-/* #undef HAVE_STD_UNORDERED_MAP */
+#define HAVE_STD_UNORDERED_MAP 1
 
 /*
  * Define if your compiler has std::unordered_set
  */
-/* #undef HAVE_STD_UNORDERED_SET */
+#define HAVE_STD_UNORDERED_SET 1
 
 /*
  * Define if your compiler has std::tr1::unordered_map
@@ -756,12 +756,12 @@
 /*
  * Define if your compiler has <tr1/type_traits>
  */
-#define HAVE_TR1_TYPE_TRAITS 1
+/* #undef HAVE_TR1_TYPE_TRAITS */
 
 /*
  * Define if your compiler has <type_traits>
  */
-/* #undef HAVE_TYPE_TRAITS */
+#define HAVE_TYPE_TRAITS 1
 
 /*
  * Define if the compiler supports simple visibility declarations.
@@ -830,7 +830,7 @@
 /*
  * Define if compiler has __thread keyword.
  */
-/* #undef HAVE___THREAD_KEYWORD */
+#define HAVE___THREAD_KEYWORD 1
 /*
  * Define if large (64 bit file offsets) files are supported.
  */
@@ -996,25 +996,25 @@
 #define HAVE_USLEEP 1
 
 /* Define if you have wcscasecmp() function  */
-/* #undef HAVE_WCSCASECMP 1 */
+#define HAVE_WCSCASECMP 1
 
 /* Define if you have wcsncasecmp() function  */
-/* #undef HAVE_WCSNCASECMP 1 */
+#define HAVE_WCSNCASECMP 1
 
 /* Define if you have wcslen function  */
 #define HAVE_WCSLEN 1
 
 /* Define if you have wcsdup function  */
-/* #undef HAVE_WCSDUP 1 */
+#define HAVE_WCSDUP 1
 
 /* Define if you have wcsftime() function  */
 #define HAVE_WCSFTIME 1
 
 /* Define if you have strnlen() function */
-/* #undef HAVE_STRNLEN 1 */
+#define HAVE_STRNLEN 1
 
 /* Define if you have wcsnlen() function */
-/* #undef HAVE_WCSNLEN 1 */
+#define HAVE_WCSNLEN 1
 
 /* Define if you have wcstoull() and wcstoll() */
 /* #undef HAVE_WCSTOULL */
diff --git a/Source/Core/Common/Src/LogManager.h b/Source/Core/Common/Src/LogManager.h
index f7ccb15034..9c3855982e 100644
--- a/Source/Core/Common/Src/LogManager.h
+++ b/Source/Core/Common/Src/LogManager.h
@@ -46,7 +46,7 @@ public:
 
 	void Log(LogTypes::LOG_LEVELS, const char *msg);
 
-	bool IsValid() { return (m_logfile != NULL); }
+	bool IsValid() { return (bool)m_logfile; }
 	bool IsEnabled() const { return m_enable; }
 	void SetEnable(bool enable) { m_enable = enable; }
 
diff --git a/Source/Core/Common/Src/StdConditionVariable.h b/Source/Core/Common/Src/StdConditionVariable.h
index 6530712c8f..85875fef10 100644
--- a/Source/Core/Common/Src/StdConditionVariable.h
+++ b/Source/Core/Common/Src/StdConditionVariable.h
@@ -5,9 +5,26 @@
 #define GCC_VER(x,y,z)	((x) * 10000 + (y) * 100 + (z))
 #define GCC_VERSION GCC_VER(__GNUC__, __GNUC_MINOR__, __GNUC_PATCHLEVEL__)
 
+#ifndef __has_include
+#define __has_include(s) 0
+#endif
+
 #if GCC_VERSION >= GCC_VER(4,4,0) && __GXX_EXPERIMENTAL_CXX0X__ && !ANDROID
+
 // GCC 4.4 provides <condition_variable>
 #include <condition_variable>
+
+#elif __has_include(<condition_variable>)
+
+// clang and libc++ provide <condition_variable> on OSX. However, the version
+// of libc++ bundled with OSX 10.7 and 10.8 is buggy: it uses _ as a variable.
+//
+// We work around this issue by undefining and redefining _.
+
+#undef _
+#include <condition_variable>
+#define _(s) wxGetTranslation((s))
+
 #else
 
 // partial std::condition_variable implementation for win32/pthread
diff --git a/Source/Core/Common/Src/StdMutex.h b/Source/Core/Common/Src/StdMutex.h
index 8a5d22f928..a20c7f744a 100644
--- a/Source/Core/Common/Src/StdMutex.h
+++ b/Source/Core/Common/Src/StdMutex.h
@@ -5,9 +5,16 @@
 #define GCC_VER(x,y,z)	((x) * 10000 + (y) * 100 + (z))
 #define GCC_VERSION GCC_VER(__GNUC__, __GNUC_MINOR__, __GNUC_PATCHLEVEL__)
 
+#ifndef __has_include
+#define __has_include(s) 0
+#endif
+
 #if GCC_VERSION >= GCC_VER(4,4,0) && __GXX_EXPERIMENTAL_CXX0X__ && !ANDROID
 // GCC 4.4 provides <mutex>
 #include <mutex>
+#elif __has_include(<mutex>)
+// Clang + libc++
+#include <mutex>
 #else
 
 // partial <mutex> implementation for win32/pthread
diff --git a/Source/Core/Common/Src/StdThread.h b/Source/Core/Common/Src/StdThread.h
index 8893c36204..19dfd60c37 100644
--- a/Source/Core/Common/Src/StdThread.h
+++ b/Source/Core/Common/Src/StdThread.h
@@ -5,12 +5,19 @@
 #define GCC_VER(x,y,z)	((x) * 10000 + (y) * 100 + (z))
 #define GCC_VERSION GCC_VER(__GNUC__, __GNUC_MINOR__, __GNUC_PATCHLEVEL__)
 
+#ifndef __has_include
+#define __has_include(s) 0
+#endif
+
 #if GCC_VERSION >= GCC_VER(4,4,0) && __GXX_EXPERIMENTAL_CXX0X__ && !ANDROID
 // GCC 4.4 provides <thread>
 #ifndef _GLIBCXX_USE_SCHED_YIELD
 #define _GLIBCXX_USE_SCHED_YIELD
 #endif
 #include <thread>
+#elif __has_include(<thread>)
+// Clang + libc++
+#include <thread>
 #else
 
 // partial std::thread implementation for win32/pthread
diff --git a/Source/Core/Common/Src/Thread.h b/Source/Core/Common/Src/Thread.h
index b5f899c43b..e35e73dbe9 100644
--- a/Source/Core/Common/Src/Thread.h
+++ b/Source/Core/Common/Src/Thread.h
@@ -18,9 +18,9 @@
 #ifndef _THREAD_H_
 #define _THREAD_H_
 
-#include "StdThread.h"
-#include "StdMutex.h"
 #include "StdConditionVariable.h"
+#include "StdMutex.h"
+#include "StdThread.h"
 
 // Don't include common.h here as it will break LogManager
 #include "CommonTypes.h"
diff --git a/Source/Core/Core/Src/HW/DSPHLE/UCodes/UCode_AX.h b/Source/Core/Core/Src/HW/DSPHLE/UCodes/UCode_AX.h
index 8fd2a2af5f..40466a81dd 100644
--- a/Source/Core/Core/Src/HW/DSPHLE/UCodes/UCode_AX.h
+++ b/Source/Core/Core/Src/HW/DSPHLE/UCodes/UCode_AX.h
@@ -75,7 +75,7 @@ public:
 	virtual void DoState(PointerWrap& p);
 
 	// Needed because StdThread.h std::thread implem does not support member
-	// pointers.
+	// pointers. TODO(delroth): obsolete.
 	static void SpawnAXThread(CUCode_AX* self);
 
 protected:
@@ -107,13 +107,13 @@ protected:
 	volatile u16 m_cmdlist[512];
 	volatile u32 m_cmdlist_size;
 
-	std::thread m_axthread;
-
 	// Sync objects
 	std::mutex m_processing;
 	std::condition_variable m_cmdlist_cv;
 	std::mutex m_cmdlist_mutex;
 
+	std::thread m_axthread;
+
 	// Copy a command list from memory to our temp buffer
 	void CopyCmdList(u32 addr, u16 size);
 
diff --git a/Source/Core/DolphinWX/Src/ConfigMain.cpp b/Source/Core/DolphinWX/Src/ConfigMain.cpp
index 85fe8d0225..4272d9ef90 100644
--- a/Source/Core/DolphinWX/Src/ConfigMain.cpp
+++ b/Source/Core/DolphinWX/Src/ConfigMain.cpp
@@ -18,6 +18,7 @@
 #include <string> // System
 #include <vector>
 #include <algorithm>
+#include <functional>
 #include <wx/spinbutt.h>
 
 #include "Common.h"
@@ -43,14 +44,6 @@
 #include "Main.h"
 #include "VideoBackendBase.h"
 
-#if defined(__APPLE__)
-#include <tr1/functional>
-using std::tr1::function;
-#else
-#include <functional>
-using std::function;
-#endif
-
 #define TEXT_BOX(page, text) new wxStaticText(page, wxID_ANY, text, wxDefaultPosition, wxDefaultSize)
 
 struct CPUCore
@@ -631,7 +624,7 @@ void CConfigMain::CreateGUIControls()
 	theme_selection->SetStringSelection(SConfig::GetInstance().m_LocalCoreStartupParameter.theme_name);
 
 	// std::function = avoid error on msvc
-	theme_selection->Bind(wxEVT_COMMAND_CHOICE_SELECTED, function<void(wxEvent&)>([theme_selection](wxEvent&)
+	theme_selection->Bind(wxEVT_COMMAND_CHOICE_SELECTED, std::function<void(wxEvent&)>([theme_selection](wxEvent&)
 	{
 		SConfig::GetInstance().m_LocalCoreStartupParameter.theme_name = theme_selection->GetStringSelection();
 		main_frame->InitBitmaps();